ATE5965T1 - Imidazol-derivate, ihre herstellung und verwendung. - Google Patents

Imidazol-derivate, ihre herstellung und verwendung.

Info

Publication number
ATE5965T1
ATE5965T1 AT80106914T AT80106914T ATE5965T1 AT E5965 T1 ATE5965 T1 AT E5965T1 AT 80106914 T AT80106914 T AT 80106914T AT 80106914 T AT80106914 T AT 80106914T AT E5965 T1 ATE5965 T1 AT E5965T1
Authority
AT
Austria
Prior art keywords
sup
sub
lower alkyl
halogen
imidazole derivatives
Prior art date
Application number
AT80106914T
Other languages
English (en)
Inventor
Rurukawa Yoshiyasu
Kishimoto Shoji
Nishikawa Kohei
Original Assignee
Takeda Chemical Industries, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries, Ltd. filed Critical Takeda Chemical Industries, Ltd.
Application granted granted Critical
Publication of ATE5965T1 publication Critical patent/ATE5965T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT80106914T 1979-11-12 1980-11-08 Imidazol-derivate, ihre herstellung und verwendung. ATE5965T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP14672979A JPS5671073A (en) 1979-11-12 1979-11-12 Imidazole derivative
EP80106914A EP0028833B1 (de) 1979-11-12 1980-11-08 Imidazol-Derivate, ihre Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
ATE5965T1 true ATE5965T1 (de) 1984-02-15

Family

ID=15414249

Family Applications (1)

Application Number Title Priority Date Filing Date
AT80106914T ATE5965T1 (de) 1979-11-12 1980-11-08 Imidazol-derivate, ihre herstellung und verwendung.

Country Status (6)

Country Link
US (1) US4340598A (de)
EP (1) EP0028833B1 (de)
JP (1) JPS5671073A (de)
AT (1) ATE5965T1 (de)
CA (1) CA1152515A (de)
DE (1) DE3066313D1 (de)

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* Cited by examiner, † Cited by third party
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US6004989A (en) 1990-04-27 1999-12-21 Takeda Chemical Industries, Ltd. Benzimidazole derivatives, their production and use
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US5506361A (en) * 1991-05-08 1996-04-09 Theupjohn Company Imidazobenzoquinones and composition for preventing or treating hypertension or congestive heart failure containing the same
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US5177097A (en) * 1991-07-24 1993-01-05 E. R. Squibb & Sons, Inc. Acyl amidine and acyl, guanidine substituted biphenyl derivatives
US5212177A (en) * 1991-12-16 1993-05-18 E. R. Squibb & Sons, Inc. Indole and benzimidazole-substituted dihydropyrimidine derivatives
US5234923A (en) * 1991-12-16 1993-08-10 E. R. Squibb & Sons, Inc. Substitute indole and benzimidazole derivatives
US5208234A (en) * 1992-03-10 1993-05-04 E. R. Squibb & Sons, Inc. Substituted imidazole phosphonic and phosphinic acid derivatives
US5616591A (en) * 1992-03-27 1997-04-01 E.R. Squibb & Sons, Inc. Indole- and benzimidazole-substituted quinoline derivatives
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US5401851A (en) * 1992-06-03 1995-03-28 Eli Lilly And Company Angiotensin II antagonists
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Family Cites Families (8)

* Cited by examiner, † Cited by third party
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FR1184709A (fr) * 1957-09-21 1959-07-24 Cfmc Nouveaux dérivés imidazoliques, utilisables comme agents de protection contre les rayons ultra-violets et leurs procédés de fabrication
US2946804A (en) * 1958-12-29 1960-07-26 Abbott Lab (5-methyl-4-imidazolyl)-diphenyl carbinol salts and lower alkyl quaternaries
US3354173A (en) * 1964-04-16 1967-11-21 Janssen Pharmaceutica Nv Imidazole carboxylates
JPS5084567A (de) * 1973-11-29 1975-07-08
US3932445A (en) * 1974-06-26 1976-01-13 Mcneil Laboratories, Incorporated 2-Aryl-4-(R-methyl)-5-methylimidazoles
CA1066709A (en) 1975-03-10 1979-11-20 Walter A.M. Helsen Preparation of loweralkyl imidazole carboxylates
US4038286A (en) * 1975-03-10 1977-07-26 Janssen Pharmaceutica N.V. Racemates and optical isomers of 1-(1-phenylethyl)-1h-imidazole-5-carboylic acid derivatives
JPS54148788A (en) * 1978-05-15 1979-11-21 Takeda Chem Ind Ltd 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative and its preparation

Also Published As

Publication number Publication date
EP0028833B1 (de) 1984-01-25
US4340598A (en) 1982-07-20
JPS5671073A (en) 1981-06-13
EP0028833A2 (de) 1981-05-20
EP0028833A3 (en) 1981-08-19
CA1152515A (en) 1983-08-23
DE3066313D1 (en) 1984-03-01

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