ATE57471T1 - Im blut identifiziertes protein, ein verfahren zu seiner zubereitung, ein verfahren fuer die bestimmung dieses proteins und ebenfalls des t-pa-hemmungsfaktors und pharmazeutische zusammensetzungen, die dieses protein enthalten. - Google Patents

Im blut identifiziertes protein, ein verfahren zu seiner zubereitung, ein verfahren fuer die bestimmung dieses proteins und ebenfalls des t-pa-hemmungsfaktors und pharmazeutische zusammensetzungen, die dieses protein enthalten.

Info

Publication number
ATE57471T1
ATE57471T1 AT86201213T AT86201213T ATE57471T1 AT E57471 T1 ATE57471 T1 AT E57471T1 AT 86201213 T AT86201213 T AT 86201213T AT 86201213 T AT86201213 T AT 86201213T AT E57471 T1 ATE57471 T1 AT E57471T1
Authority
AT
Austria
Prior art keywords
protein
pharmaceutical compositions
compositions containing
relates
blood
Prior art date
Application number
AT86201213T
Other languages
English (en)
Inventor
Cornelis Kluft
Original Assignee
Tno
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tno filed Critical Tno
Application granted granted Critical
Publication of ATE57471T1 publication Critical patent/ATE57471T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8132—Plasminogen activator inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT86201213T 1985-07-12 1986-07-10 Im blut identifiziertes protein, ein verfahren zu seiner zubereitung, ein verfahren fuer die bestimmung dieses proteins und ebenfalls des t-pa-hemmungsfaktors und pharmazeutische zusammensetzungen, die dieses protein enthalten. ATE57471T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8502017A NL8502017A (nl) 1985-07-12 1985-07-12 Nieuw, in het bloed geidentificeerd eiwit, werkwijze ter bereiding daarvan, werkwijze ter bepaling van dit eiwit en tevens van t-pa-remmer, en farmaceutische preparaten die het eiwit bevatten.
EP86201213A EP0208383B1 (de) 1985-07-12 1986-07-10 Im Blut identifiziertes Protein, ein Verfahren zu seiner Zubereitung, ein Verfahren für die Bestimmung dieses Proteins und ebenfalls des t-PA-Hemmungsfaktors und pharmazeutische Zusammensetzungen, die dieses Protein enthalten

Publications (1)

Publication Number Publication Date
ATE57471T1 true ATE57471T1 (de) 1990-11-15

Family

ID=19846293

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86201213T ATE57471T1 (de) 1985-07-12 1986-07-10 Im blut identifiziertes protein, ein verfahren zu seiner zubereitung, ein verfahren fuer die bestimmung dieses proteins und ebenfalls des t-pa-hemmungsfaktors und pharmazeutische zusammensetzungen, die dieses protein enthalten.

Country Status (6)

Country Link
US (1) US5004802A (de)
EP (1) EP0208383B1 (de)
JP (1) JP2512437B2 (de)
AT (1) ATE57471T1 (de)
DE (1) DE3674955D1 (de)
NL (1) NL8502017A (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5372719A (en) * 1992-03-30 1994-12-13 Perseptive Biosystems, Inc. Molecular imaging
US5474766A (en) * 1992-12-18 1995-12-12 Washington University Methods and compositions for inhibition of hepatic clearance of tissue-type plasminogen activator
US5607841A (en) * 1994-06-20 1997-03-04 Lipinski; Boguslaw Preparation and proteolytic degradation of a macromolecular protein complex from fibrinogen
US10160813B2 (en) 2013-01-22 2018-12-25 University Of Tennessee Research Foundation Tissue plasminogen activator antibodies and methods of use

Also Published As

Publication number Publication date
JP2512437B2 (ja) 1996-07-03
US5004802A (en) 1991-04-02
DE3674955D1 (de) 1990-11-22
JPS6277326A (ja) 1987-04-09
NL8502017A (nl) 1987-02-02
EP0208383A1 (de) 1987-01-14
EP0208383B1 (de) 1990-10-17

Similar Documents

Publication Publication Date Title
Stricklin et al. Human skin collagenase: isolation of precursor and active forms from both fibroblast and organ cultures
Content et al. Secretory proteins induced in human fibroblasts under conditions used for the production of interferon beta.
Kagan et al. Purification and properties of four species of lysyl oxidase from bovine aorta
Summaria et al. Isolation and characterization of the affinity chromatography forms of human Glu-and Lys-plasminogens and plasmins.
BG60256B1 (bg) Рекомбинантен метод за получаване на лимфотоксин
Silverstein et al. Tissue plasminogen activator and urokinase enhance the binding of plasminogen to thrombospondin.
Kohno et al. Kidney plasminogen activator: a precursor form of human urokinase with high fibrin affinity
Havell et al. Altered molecular species of human interferon produced in the presence of inhibitors of glycosylation.
Deogny et al. Improved fibrin plate method for fibrinolytic activity measurements: use of bentonite precipitation and agar solidification
ATE113960T1 (de) Proteingewinnung.
Dahl et al. Enhancement of urokinase-induced plasminogen activation by the cationic protein of human eosinophil granulocytes
Sia et al. Studies on the subunit structure of rabbit liver fructose diphosphatase
Thorsen et al. Sequence of formation of molecular forms of plasminogen and plasmin-inhibitor complexes in plasma activated by urokinase or tissue-type plasminogen activator
EP0256836A1 (de) Verfahren zur Reinigung von TPA aus rohen Präparaten
Boyes et al. Purification of an insulin‐sensitive cyclic AMP phosphodiesterase from rat liver
Kruithof et al. Influence of detergents on the measurement of the fibrinolytic activity of plasminogen activators
ATE57471T1 (de) Im blut identifiziertes protein, ein verfahren zu seiner zubereitung, ein verfahren fuer die bestimmung dieses proteins und ebenfalls des t-pa-hemmungsfaktors und pharmazeutische zusammensetzungen, die dieses protein enthalten.
Livingstone et al. The purification and preliminary characterization of UMP synthase from human placenta.
Franklin et al. Chromatographic evidence for the existence of multiple forms of cathepsin B1
Wicher et al. Interactions of Bacillus subtilis alkaline proteinases with α2-macroglobulin and α1-antitrypsin
Lundblad et al. The covalent differences between bovine alpha-and beta-thrombin. A structural explanation for the changes in catalytic activity.
York et al. Interaction of fragments of fibrinogen with insolubilized fibrin monomers (activated fibrinogen)
Robinson et al. Trypsins In Human Pancreatic Juice–Their Distribution as Found in 34 Specimens. Two Human Pancreatic Trypsinogens
Gache et al. Susceptibility of platelet α-actinin to a Ca2+-activated neutral protease
Markland et al. Resolution of isoforms of natural and recombinant fibrinolytic snake venom enzyme using high performance capillary electrophoresis

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee