ATE56012T1 - Indolo-(6,5,4-cd)-indol derivate und verfahren zu deren herstellung. - Google Patents

Indolo-(6,5,4-cd)-indol derivate und verfahren zu deren herstellung.

Info

Publication number
ATE56012T1
ATE56012T1 AT85305218T AT85305218T ATE56012T1 AT E56012 T1 ATE56012 T1 AT E56012T1 AT 85305218 T AT85305218 T AT 85305218T AT 85305218 T AT85305218 T AT 85305218T AT E56012 T1 ATE56012 T1 AT E56012T1
Authority
AT
Austria
Prior art keywords
indolo
manufacture
sup
indole derivatives
sub
Prior art date
Application number
AT85305218T
Other languages
English (en)
Inventor
William Hubert Hunter
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Application granted granted Critical
Publication of ATE56012T1 publication Critical patent/ATE56012T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT85305218T 1984-07-27 1985-07-23 Indolo-(6,5,4-cd)-indol derivate und verfahren zu deren herstellung. ATE56012T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848419278A GB8419278D0 (en) 1984-07-27 1984-07-27 Pharmaceutical compounds
EP85305218A EP0176182B1 (de) 1984-07-27 1985-07-23 Indolo-(6,5,4-cd)-indol Derivate und Verfahren zu deren Herstellung

Publications (1)

Publication Number Publication Date
ATE56012T1 true ATE56012T1 (de) 1990-09-15

Family

ID=10564592

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85305218T ATE56012T1 (de) 1984-07-27 1985-07-23 Indolo-(6,5,4-cd)-indol derivate und verfahren zu deren herstellung.

Country Status (7)

Country Link
US (2) US4742075A (de)
EP (1) EP0176182B1 (de)
JP (1) JPS6143189A (de)
AT (1) ATE56012T1 (de)
DE (1) DE3579401D1 (de)
GB (2) GB8419278D0 (de)
IL (1) IL75887A (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8608893D0 (en) * 1986-04-11 1986-05-14 Erba Farmitalia D-nor-7-ergoline derivatives
WO2018064465A1 (en) 2016-09-29 2018-04-05 The Regents Of The University Of California Compounds for increasing neural plasticity
CA3130770A1 (en) 2019-02-27 2020-09-03 The Regents Of The University Of California Azepino-indoles and other heterocycles for treating brain disorders
KR20210134928A (ko) 2019-02-27 2021-11-11 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 뇌 장애를 치료하기 위한 n-치환된 인돌 및 다른 헤테로사이클
WO2021076572A1 (en) * 2019-10-14 2021-04-22 The Regents Of The University Of California Ergoline-like compounds for promoting neural plasticity
TW202333668A (zh) 2021-12-15 2023-09-01 美商德利克斯醫療公司 經苯氧基及苄氧基取代之精神成形素(psychoplastogen)及其用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1482871A (en) * 1975-03-18 1977-08-17 Farmaceutici Italia Tetracyclic indole derivatives
AR223177A1 (es) * 1978-05-23 1981-07-31 Lilly Industries Ltd Procedimiento para preparar derivados de indolo-isoquinolina
US4201862A (en) * 1979-03-16 1980-05-06 Eli Lilly And Company 2-Azaergolines and 2-aza-8(or 9)-ergolenes
IL59507A (en) * 1979-03-16 1984-01-31 Erba Farmitalia 5-(10-9)abeo-6-methylergoline derivatives,their preparation and pharmaceutical compositions containing them
GB2056437A (en) * 1979-08-07 1981-03-18 Erba Farmitalia Secoergoline derivatives

Also Published As

Publication number Publication date
EP0176182A3 (en) 1986-05-14
JPS6143189A (ja) 1986-03-01
GB2162182A (en) 1986-01-29
EP0176182A2 (de) 1986-04-02
GB2162182B (en) 1989-04-12
GB8518628D0 (en) 1985-08-29
US4742075A (en) 1988-05-03
IL75887A0 (en) 1985-12-31
DE3579401D1 (de) 1990-10-04
IL75887A (en) 1988-05-31
US4841056A (en) 1989-06-20
GB8419278D0 (en) 1984-08-30
EP0176182B1 (de) 1990-08-29

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee