IL75887A - 9-substituted-indolo(6,5,4-cd)indole derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
9-substituted-indolo(6,5,4-cd)indole derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL75887A IL75887A IL75887A IL7588785A IL75887A IL 75887 A IL75887 A IL 75887A IL 75887 A IL75887 A IL 75887A IL 7588785 A IL7588785 A IL 7588785A IL 75887 A IL75887 A IL 75887A
- Authority
- IL
- Israel
- Prior art keywords
- indolo
- substituted
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- -1 9-substituted-indolo(6,5,4-cd)indole Chemical class 0.000 title 1
- 229940054051 antipsychotic indole derivative Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB848419278A GB8419278D0 (en) | 1984-07-27 | 1984-07-27 | Pharmaceutical compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL75887A0 IL75887A0 (en) | 1985-12-31 |
| IL75887A true IL75887A (en) | 1988-05-31 |
Family
ID=10564592
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL75887A IL75887A (en) | 1984-07-27 | 1985-07-23 | 9-substituted-indolo(6,5,4-cd)indole derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US4742075A (de) |
| EP (1) | EP0176182B1 (de) |
| JP (1) | JPS6143189A (de) |
| AT (1) | ATE56012T1 (de) |
| DE (1) | DE3579401D1 (de) |
| GB (2) | GB8419278D0 (de) |
| IL (1) | IL75887A (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8608893D0 (en) * | 1986-04-11 | 1986-05-14 | Erba Farmitalia | D-nor-7-ergoline derivatives |
| WO2018064465A1 (en) | 2016-09-29 | 2018-04-05 | The Regents Of The University Of California | Compounds for increasing neural plasticity |
| JP7770673B2 (ja) | 2019-02-27 | 2025-11-17 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 脳障害を治療するためのアゼピノ－インドール及び他の複素環化合物 |
| WO2020176597A1 (en) | 2019-02-27 | 2020-09-03 | The Regents Of The University Of California | N-substituted indoles and other heterocycles for treating brain disorders |
| WO2021076572A1 (en) * | 2019-10-14 | 2021-04-22 | The Regents Of The University Of California | Ergoline-like compounds for promoting neural plasticity |
| AU2022416279A1 (en) | 2021-12-15 | 2024-07-25 | Delix Therapeutics, Inc. | Phenoxy and benzyloxy substituted psychoplastogens and uses thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1482871A (en) * | 1975-03-18 | 1977-08-17 | Farmaceutici Italia | Tetracyclic indole derivatives |
| IL57344A (en) * | 1978-05-23 | 1982-05-31 | Lilly Industries Ltd | Indolo(4,3-fg)-and indolo(3,4-gh)isoquinolines,their preparation and pharmaceutical compositions containing them |
| US4201862A (en) * | 1979-03-16 | 1980-05-06 | Eli Lilly And Company | 2-Azaergolines and 2-aza-8(or 9)-ergolenes |
| IL59507A (en) * | 1979-03-16 | 1984-01-31 | Erba Farmitalia | 5-(10-9)abeo-6-methylergoline derivatives,their preparation and pharmaceutical compositions containing them |
| GB2056437A (en) * | 1979-08-07 | 1981-03-18 | Erba Farmitalia | Secoergoline derivatives |
-
1984
- 1984-07-27 GB GB848419278A patent/GB8419278D0/en active Pending
-
1985
- 1985-07-22 US US06/757,223 patent/US4742075A/en not_active Expired - Fee Related
- 1985-07-23 DE DE8585305218T patent/DE3579401D1/de not_active Expired - Fee Related
- 1985-07-23 IL IL75887A patent/IL75887A/xx not_active IP Right Cessation
- 1985-07-23 EP EP85305218A patent/EP0176182B1/de not_active Expired - Lifetime
- 1985-07-23 GB GB8518628A patent/GB2162182B/en not_active Expired
- 1985-07-23 AT AT85305218T patent/ATE56012T1/de not_active IP Right Cessation
- 1985-07-26 JP JP60165648A patent/JPS6143189A/ja active Pending
-
1988
- 1988-01-27 US US07/148,807 patent/US4841056A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| GB2162182B (en) | 1989-04-12 |
| DE3579401D1 (de) | 1990-10-04 |
| US4841056A (en) | 1989-06-20 |
| EP0176182A3 (en) | 1986-05-14 |
| EP0176182B1 (de) | 1990-08-29 |
| GB8419278D0 (en) | 1984-08-30 |
| EP0176182A2 (de) | 1986-04-02 |
| GB2162182A (en) | 1986-01-29 |
| JPS6143189A (ja) | 1986-03-01 |
| GB8518628D0 (en) | 1985-08-29 |
| ATE56012T1 (de) | 1990-09-15 |
| IL75887A0 (en) | 1985-12-31 |
| US4742075A (en) | 1988-05-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |