ATE553766T1 - Zubereitung und xenotransplantation von langerhans-inseln von schweinen - Google Patents

Zubereitung und xenotransplantation von langerhans-inseln von schweinen

Info

Publication number
ATE553766T1
ATE553766T1 AT01979134T AT01979134T ATE553766T1 AT E553766 T1 ATE553766 T1 AT E553766T1 AT 01979134 T AT01979134 T AT 01979134T AT 01979134 T AT01979134 T AT 01979134T AT E553766 T1 ATE553766 T1 AT E553766T1
Authority
AT
Austria
Prior art keywords
pancreas
preparation
islets
culture
xenotransplantation
Prior art date
Application number
AT01979134T
Other languages
English (en)
Inventor
Professor Robert Bartlet Elliott
Guiseppe Basta
Giovanni Luca
Riccardo Calafiore
Original Assignee
Diabcell Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from NZ50761600A external-priority patent/NZ507616A/en
Application filed by Diabcell Pty Ltd filed Critical Diabcell Pty Ltd
Application granted granted Critical
Publication of ATE553766T1 publication Critical patent/ATE553766T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/39—Pancreas; Islets of Langerhans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Developmental Biology & Embryology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
AT01979134T 2000-10-17 2001-10-16 Zubereitung und xenotransplantation von langerhans-inseln von schweinen ATE553766T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NZ50761600A NZ507616A (en) 2000-10-17 2000-10-17 Preparation and xenotransplantation of porcine islets in the presence of sertoli cells, for treatment of diabetes
NZ50796300 2000-11-02
PCT/NZ2001/000228 WO2002032437A1 (en) 2000-10-17 2001-10-16 Preparation and xenotransplantation or porcine islets

Publications (1)

Publication Number Publication Date
ATE553766T1 true ATE553766T1 (de) 2012-05-15

Family

ID=26652219

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01979134T ATE553766T1 (de) 2000-10-17 2001-10-16 Zubereitung und xenotransplantation von langerhans-inseln von schweinen

Country Status (7)

Country Link
US (2) US20040014212A1 (de)
EP (1) EP1333846B1 (de)
AT (1) ATE553766T1 (de)
AU (2) AU2002211122B2 (de)
DK (1) DK1333846T3 (de)
ES (1) ES2386505T3 (de)
WO (1) WO2002032437A1 (de)

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US20050265977A1 (en) * 1999-04-30 2005-12-01 Elliott Robert B Xenotransplant for CNS therapy
DK1176970T3 (da) * 1999-04-30 2010-09-20 Neurotrophincell Pty Ltd Xenotransplantat til CNS-terapi
US20030108539A1 (en) * 2000-02-14 2003-06-12 Christophe Bonny Cell-permeable peptide inhibitors of the JNK signal transduction pathway
EP1248640B1 (de) * 2000-01-20 2006-10-04 Diabcell Pty Limited Präparation und xenotransplantation von inseln aus schweinen
WO2003027270A1 (en) * 2001-09-28 2003-04-03 Diabcell Pty Limited Growing xenotransplant material in culture
NZ515310A (en) * 2001-11-07 2004-08-27 Diabcell Pty Ltd Methods of treatment and delivery modes
WO2004113516A1 (en) * 2003-06-24 2004-12-29 Diabcell Pty Limited Porcine islets cultured with porcine sertoli cells for xenotransplantation
CA2848954A1 (en) * 2003-07-03 2005-03-03 Sertoli Technologies, Llc Compositions containing sertoli cells and myoid cells and use thereof in cellular transplants
NZ539491A (en) 2005-04-15 2008-04-30 Living Cell Products Pty Ltd Swine population and uses thereof
NZ536009A (en) 2005-04-18 2007-01-26 Neurotrophincell Pty Ltd Choroid plexus preparation and uses thereof
NZ540597A (en) * 2005-06-08 2007-02-23 Neurotrophincell Pty Ltd A method for preventing the onset of type I diabetes comprising administering an implantable composition comprising living choroid plexus cells
WO2007031098A1 (en) 2005-09-12 2007-03-22 Xigen S.A. Cell-permeable peptide inhibitors of the jnk signal transduction pathway
JP2010500871A (ja) * 2006-07-28 2010-01-14 セルトセル・バイオテクノロジー・（ユーエス）・コーポレイション 成熟セルトリ細胞およびその使用
WO2009143865A1 (en) 2008-05-30 2009-12-03 Xigen S.A. Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
WO2009143864A1 (en) 2008-05-30 2009-12-03 Xigen S.A. Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of chronic or non-chronic inflammatory digestive diseases
WO2010072228A1 (en) 2008-12-22 2010-07-01 Xigen S.A. Novel transporter constructs and transporter cargo conjugate molecules
ES2653241T3 (es) * 2009-08-28 2018-02-06 Sernova Corporation Métodos y dispositivos para trasplante celular
WO2011160653A1 (en) 2010-06-21 2011-12-29 Xigen S.A. Novel jnk inhibitor molecules
US9150618B2 (en) 2010-10-14 2015-10-06 Xigen Inflammation Ltd. Use of cell-permeable peptide inhibitors of the JNK signal transduction pathway for the treatment of chronic or non-chronic inflammatory eye diseases
US20130336940A1 (en) 2011-02-23 2013-12-19 Universite Catholique De Louvain Modified pig islets for diabetes treatment
US9810803B2 (en) * 2011-03-23 2017-11-07 Seismic Global Ambient, Llc Method for subsurface mapping using seismic emissions
US9389326B2 (en) * 2011-03-23 2016-07-12 Global Ambient Seismic, Inc. Methods, systems and devices for near-well fracture monitoring using tomographic fracture imaging techniques
US9442205B2 (en) * 2011-03-23 2016-09-13 Global Ambient Seismic, Inc. Method for assessing the effectiveness of modifying transmissive networks of natural reservoirs
US9557433B2 (en) * 2011-03-23 2017-01-31 Seismic Global Ambient, Llc Fracture imaging methods employing skeletonization of seismic emission tomography data
WO2013091670A1 (en) 2011-12-21 2013-06-27 Xigen S.A. Novel jnk inhibitor molecules for treatment of various diseases
WO2014206427A1 (en) 2013-06-26 2014-12-31 Xigen Inflammation Ltd. New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
CN105307670A (zh) 2013-06-26 2016-02-03 埃克西金炎症有限公司 Jnk信号转导途径的细胞渗透肽抑制剂用于治疗多种疾病的新用途
WO2015197097A1 (en) 2014-06-26 2015-12-30 Xigen Inflammation Ltd. New use for jnk inhibitor molecules for treatment of various diseases
DK3129467T3 (da) 2014-04-11 2020-02-10 Univ Catholique Louvain Transgene svineøer og anvendelser deraf til behandling af diabetes
KR20220132600A (ko) * 2020-01-28 2022-09-30 가부시키가이샤 오츠까 세이야꾸 고죠 췌도 함유 캡슐의 제조 방법
CA3187454A1 (en) * 2020-06-17 2021-12-23 Otsuka Pharmaceutical Factory, Inc. Encapsulated pancreatic islet

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US20050265977A1 (en) * 1999-04-30 2005-12-01 Elliott Robert B Xenotransplant for CNS therapy
US20040213768A1 (en) * 1999-04-30 2004-10-28 Elliott Robert Bartlett Preparation for biotransplantation and xenotransplantion and uses thereof
EP1248640B1 (de) * 2000-01-20 2006-10-04 Diabcell Pty Limited Präparation und xenotransplantation von inseln aus schweinen
NZ515310A (en) * 2001-11-07 2004-08-27 Diabcell Pty Ltd Methods of treatment and delivery modes

Also Published As

Publication number Publication date
EP1333846B1 (de) 2012-04-18
AU2002211122B2 (en) 2005-06-23
WO2002032437A1 (en) 2002-04-25
US20080070301A1 (en) 2008-03-20
US20040014212A1 (en) 2004-01-22
AU1112202A (en) 2002-04-29
ES2386505T3 (es) 2012-08-22
EP1333846A4 (de) 2008-02-20
DK1333846T3 (da) 2012-08-06
EP1333846A1 (de) 2003-08-13

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