ATE552501T1 - Identifizierung und überwachung von systemischem lupus erythematodes - Google Patents

Identifizierung und überwachung von systemischem lupus erythematodes

Info

Publication number
ATE552501T1
ATE552501T1 AT04759986T AT04759986T ATE552501T1 AT E552501 T1 ATE552501 T1 AT E552501T1 AT 04759986 T AT04759986 T AT 04759986T AT 04759986 T AT04759986 T AT 04759986T AT E552501 T1 ATE552501 T1 AT E552501T1
Authority
AT
Austria
Prior art keywords
monitoring
platelets
erythematode
identification
systemic lupus
Prior art date
Application number
AT04759986T
Other languages
German (de)
English (en)
Inventor
Joseph Ahearn
Susan Manzi
Jeannine Navratil
Original Assignee
Univ Pittsburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pittsburgh filed Critical Univ Pittsburgh
Application granted granted Critical
Publication of ATE552501T1 publication Critical patent/ATE552501T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/10Musculoskeletal or connective tissue disorders
    • G01N2800/101Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
    • G01N2800/104Lupus erythematosus [SLE]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/967Standards, controls, materials, e.g. validation studies, buffer systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/973Simultaneous determination of more than one analyte
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/811Test for named disease, body condition or organ function
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/821Chemistry: analytical and immunological testing involving complement factors or complement systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666Particle count or volume standard or control [e.g., platelet count standards, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Rehabilitation Therapy (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Dc Digital Transmission (AREA)
  • Small-Scale Networks (AREA)
  • Testing Of Coins (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
AT04759986T 2003-04-16 2004-04-16 Identifizierung und überwachung von systemischem lupus erythematodes ATE552501T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46344703P 2003-04-16 2003-04-16
PCT/US2004/011982 WO2004093647A2 (en) 2003-04-16 2004-04-16 Identification and monitoring of systematic lupus erythematosus

Publications (1)

Publication Number Publication Date
ATE552501T1 true ATE552501T1 (de) 2012-04-15

Family

ID=33310779

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04759986T ATE552501T1 (de) 2003-04-16 2004-04-16 Identifizierung und überwachung von systemischem lupus erythematodes

Country Status (7)

Country Link
US (3) US7588905B2 (https=)
EP (1) EP1618379B1 (https=)
JP (1) JP4550051B2 (https=)
AT (1) ATE552501T1 (https=)
AU (1) AU2004232007B2 (https=)
CA (1) CA2522261A1 (https=)
WO (1) WO2004093647A2 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA200510325B (en) 2003-06-13 2008-04-30 Univ Pittsburgh Monitoring immunologic, hematologic and inflammatory diseases
US20080131914A1 (en) * 2005-09-14 2008-06-05 Ahearn Joseph M Assessing risk of cerebrovascular thrombosis by measuring c4d
US8062852B2 (en) 2007-10-01 2011-11-22 The Children's Hospital And Regional Medical Center Detection and treatment of autoimmune disorders
US20100233752A1 (en) * 2008-10-16 2010-09-16 Cypress Bioscience, Inc. Method for diagnosis and monitoring of disease activity and response to treatment in systemic lupus erythematosus (sle) and other autoimmune diseases
JP5625155B2 (ja) * 2010-07-30 2014-11-19 国立大学法人 東京大学 ホスファチジルセリン特異的ホスホリパーゼa1測定による全身性エリテマトーデスの検査方法および検査薬
EP2673644B1 (en) 2011-02-11 2016-02-10 Exagen Diagnostics, Inc. Methods for diagnosing systemic lupus erythematosus
RU2019103573A (ru) 2013-02-08 2019-03-15 Аллегени-Сингер Рисерч Инститьют Клеточно-связанные продукты активации комплемента в качестве диагностических биомаркеров волчанки в доклинической стадии
US9863946B2 (en) 2013-02-08 2018-01-09 Allegheny-Singer Research Institute Cell-bound complement activation products as diagnostic biomarkers for pre-lupus
WO2014151238A1 (en) 2013-03-15 2014-09-25 Exagen Diagnostics, Inc. Methods for treating and diagnosing systemic lupus erythematosus
US10105413B2 (en) 2013-06-13 2018-10-23 Medical Research & Development Fund for Health Services Bnai Zion Medical Center Semaphorin 3A for treatment of systemic lupus erythematosus
CA2990722C (en) 2015-07-31 2022-07-05 Allegheny-Singer Research Institute Cell-bound complement activation product assays as companion diagnostics for antibody-based drugs
US12130288B2 (en) 2016-05-24 2024-10-29 Allegheny Singer Research Institute Methods and systems using C4 gene copy number and cell-bound complement activation products for identification of lupus and pre-lupus
CA3203051A1 (en) * 2020-12-21 2022-06-30 Zaverio M. Ruggeri Method for evaluating blood parameters

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0666987A4 (en) 1992-10-30 1997-08-27 T Cell Diagnostics Inc EVALUATION OF THE TOTAL QUANTITY OF A MOLECULE IN A SAMPLE AND METHODS BASED ON SAME.
WO1999045094A1 (en) * 1998-03-02 1999-09-10 Compucyte Corp. Selective cell analysis
JP4570872B2 (ja) * 2001-09-10 2010-10-27 ユニヴァーシティ オブ ピッツバーグ 全身性紅斑性狼瘡および強皮症の診断およびモニタリング方法
ZA200510325B (en) * 2003-06-13 2008-04-30 Univ Pittsburgh Monitoring immunologic, hematologic and inflammatory diseases
EP1756571B8 (en) * 2004-04-09 2010-10-13 University of Pittsburgh - Of the Commonwealth System of Higher Education Real time method of detecting acute inflammatory conditions
CA2564492C (en) * 2004-05-11 2012-05-22 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Diagnosing and monitoring inflammatory diseases by measuring complement components on white blood cells
US7679298B2 (en) * 2006-08-17 2010-03-16 General Electric Company Locomotive wheel speed control

Also Published As

Publication number Publication date
US20120122241A1 (en) 2012-05-17
US8126654B2 (en) 2012-02-28
JP2006524342A (ja) 2006-10-26
EP1618379B1 (en) 2012-04-04
US20070178536A1 (en) 2007-08-02
AU2004232007A1 (en) 2004-11-04
EP1618379A4 (en) 2008-05-07
WO2004093647A2 (en) 2004-11-04
US20090299948A1 (en) 2009-12-03
WO2004093647A3 (en) 2005-03-10
AU2004232007B2 (en) 2009-10-22
US7588905B2 (en) 2009-09-15
CA2522261A1 (en) 2004-11-04
JP4550051B2 (ja) 2010-09-22
EP1618379A2 (en) 2006-01-25

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