ATE549346T1 - Chemische modifikation von proteinen - Google Patents

Chemische modifikation von proteinen

Info

Publication number
ATE549346T1
ATE549346T1 AT09712051T AT09712051T ATE549346T1 AT E549346 T1 ATE549346 T1 AT E549346T1 AT 09712051 T AT09712051 T AT 09712051T AT 09712051 T AT09712051 T AT 09712051T AT E549346 T1 ATE549346 T1 AT E549346T1
Authority
AT
Austria
Prior art keywords
cysteine
residue
peptide
protein
synthesis
Prior art date
Application number
AT09712051T
Other languages
English (en)
Inventor
Goncalo Bernardes
Justin Chalker
Benjamin Davis
Original Assignee
Isis Innovation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isis Innovation filed Critical Isis Innovation
Application granted granted Critical
Publication of ATE549346T1 publication Critical patent/ATE549346T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • C07K1/026General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution by fragment condensation in solution
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/13Labelling of peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT09712051T 2008-02-22 2009-01-23 Chemische modifikation von proteinen ATE549346T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0803315.1A GB0803315D0 (en) 2008-02-22 2008-02-22 Chemical modification of proteins
PCT/GB2009/000194 WO2009103941A1 (en) 2008-02-22 2009-01-23 Chemical modification of proteins

Publications (1)

Publication Number Publication Date
ATE549346T1 true ATE549346T1 (de) 2012-03-15

Family

ID=39284435

Family Applications (1)

Application Number Title Priority Date Filing Date
AT09712051T ATE549346T1 (de) 2008-02-22 2009-01-23 Chemische modifikation von proteinen

Country Status (5)

Country Link
US (2) US9346851B2 (de)
EP (1) EP2254900B1 (de)
AT (1) ATE549346T1 (de)
GB (1) GB0803315D0 (de)
WO (1) WO2009103941A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0810418D0 (en) * 2008-06-06 2008-07-09 Isis Innovation Method
WO2013084198A1 (en) 2011-12-07 2013-06-13 Universidade De Lisboa Chemical modification and bioconjugation of proteins or peptides using boron compounds
US10723760B2 (en) * 2016-09-02 2020-07-28 Korea Advanced Institute Of Science And Technology Method for preparing site-specifically modified protein based on novel carbon-carbon bond formation
WO2018044130A1 (ko) * 2016-09-02 2018-03-08 한국과학기술원 새로운 탄소-탄소 결합 기반 위치 특이적으로 변형된 단백질의 제조방법
EP3871665B1 (de) 2020-02-28 2025-12-24 Martin-Luther-Universität Halle-Wittenberg Inhibitoren von rna-bindenden proteinen als antikrebsmittel

Also Published As

Publication number Publication date
EP2254900B1 (de) 2012-03-14
US20160326212A1 (en) 2016-11-10
EP2254900A1 (de) 2010-12-01
US20110144304A1 (en) 2011-06-16
GB0803315D0 (en) 2008-04-02
US9346851B2 (en) 2016-05-24
WO2009103941A1 (en) 2009-08-27

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