ATE545012T1 - VORRICHTUNGEN UND VERFAHREN ZUR ABBILDUNG VON OBJEKTEN MITTELS ßTIME DELAY INTEGRATIONß - Google Patents

VORRICHTUNGEN UND VERFAHREN ZUR ABBILDUNG VON OBJEKTEN MITTELS ßTIME DELAY INTEGRATIONß

Info

Publication number
ATE545012T1
ATE545012T1 AT04816174T AT04816174T ATE545012T1 AT E545012 T1 ATE545012 T1 AT E545012T1 AT 04816174 T AT04816174 T AT 04816174T AT 04816174 T AT04816174 T AT 04816174T AT E545012 T1 ATE545012 T1 AT E545012T1
Authority
AT
Austria
Prior art keywords
tdi
time delay
devices
objects
delay integration
Prior art date
Application number
AT04816174T
Other languages
English (en)
Inventor
Jan Greve
Frederick Schreuder
Leon Terstappen
Arjan Tibbe
Original Assignee
Immunivest Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunivest Corp filed Critical Immunivest Corp
Application granted granted Critical
Publication of ATE545012T1 publication Critical patent/ATE545012T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/5759—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1497—Particle shape

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Solid State Image Pick-Up Elements (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT04816174T 2003-08-11 2004-08-10 VORRICHTUNGEN UND VERFAHREN ZUR ABBILDUNG VON OBJEKTEN MITTELS ßTIME DELAY INTEGRATIONß ATE545012T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49410103P 2003-08-11 2003-08-11
PCT/US2004/025981 WO2005027037A2 (en) 2002-05-01 2004-08-10 Devices and methods to image objects by time delay integration

Publications (1)

Publication Number Publication Date
ATE545012T1 true ATE545012T1 (de) 2012-02-15

Family

ID=36177491

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04816174T ATE545012T1 (de) 2003-08-11 2004-08-10 VORRICHTUNGEN UND VERFAHREN ZUR ABBILDUNG VON OBJEKTEN MITTELS ßTIME DELAY INTEGRATIONß

Country Status (5)

Country Link
EP (1) EP1656545B1 (de)
JP (1) JP2007502419A (de)
AT (1) ATE545012T1 (de)
CA (1) CA2535301A1 (de)
WO (1) WO2005027037A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4491391B2 (ja) * 2005-08-05 2010-06-30 株式会社日立ハイテクノロジーズ 欠陥検査装置及び欠陥検査方法
EP2024893B1 (de) * 2006-05-12 2015-03-04 Janssen Diagnostics, LLC Laserbeleuchtungssystem in einem fluoreszenzmikroskop
JP5020118B2 (ja) * 2008-02-18 2012-09-05 浜松ホトニクス株式会社 蛍光解析装置及び解析方法
US8569077B2 (en) * 2008-05-19 2013-10-29 Veridex, Llc Imaging of immunomagnetically enriched rare cells
CN102439416B (zh) * 2009-03-20 2015-11-25 伯乐实验室有限公司 串行线扫描编码多色荧光显微术及成像流式细胞仪
WO2011108454A1 (ja) * 2010-03-05 2011-09-09 コニカミノルタホールディングス株式会社 細胞の検出方法及び細胞検出システム
US8761486B2 (en) * 2011-02-22 2014-06-24 Bio-Rad Laboratories, Inc. Line scan cytometry systems and methods
US9049353B2 (en) 2011-09-28 2015-06-02 Semiconductor Components Industries, Llc Time-delay-and-integrate image sensors having variable integration times
JPWO2014097991A1 (ja) * 2012-12-18 2017-01-12 コニカミノルタ株式会社 希少細胞検出装置、希少細胞検出方法、希少細胞観察システム、および細胞展開用デバイス
CN104266956A (zh) * 2014-09-02 2015-01-07 上海凯度机电科技有限公司 高内涵图像流式生物显微分析方法
CN106645045B (zh) * 2016-09-09 2020-01-21 华中科技大学 一种荧光光学显微成像中基于tdi-ccd的双向扫描成像方法
EP4105642A4 (de) * 2020-02-12 2023-11-29 MGI Tech Co., Ltd. Optisches abbildungssystem und system zur detektion von biochemischen substanzen damit

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5470710A (en) * 1993-10-22 1995-11-28 University Of Utah Automated hybridization/imaging device for fluorescent multiplex DNA sequencing
US6151405A (en) * 1996-11-27 2000-11-21 Chromavision Medical Systems, Inc. System and method for cellular specimen grading
BR9907852A (pt) * 1998-02-12 2000-10-24 Immunivest Corp Processos para detectar e enumerar células raras e cancerosas em uma população celular mista, para diagnosticar câncer de estágio precoce em um paciente de teste, para determinar a probabilidade de recorrência de câncer em um paciente humano anteriormente tratado de câncer, para distinguir um carcinoma confinado ao órgão de um carcinoma com propriedades metastáticas, para acompanhar a situação de remissão em um paciente humano com câncer que passa pelo tratamento de terapia contra o câncer e para aumentar quantidades de células epiteliais circulantes em uma amostra de sangue, partìcula magnética revestida, composição, conjuntos de teste para avaliar uma amostra de paciente quanto a presença de células raras circulantes, quanto a presença de células de tumor circulantes, quanto a presença de células de câncer de mama circulantes, quanto a presença de células de câncer de próstata circulantes, quanto a presença de células de câncer de cólon circulantes, quanto a presença de células de câncer de bexiga circulantes e para monitorar um paciente quanto a recorrência de câncer, e, fração de sangue periférico enriquecido quanto a células neoplásticas circulantes
BR0206255A (pt) * 2001-01-05 2003-12-23 Immunivest Corp Métodos e aparelhos para geração de imagens analìticas de entidades alvo e para varrer automaticamente objetos do tamanho de mìcrons magneticamente e detectavelmente rotulados localizados em uma superfìcie plana
US20030048933A1 (en) * 2001-08-08 2003-03-13 Brown Carl S. Time-delay integration imaging of biological specimen

Also Published As

Publication number Publication date
CA2535301A1 (en) 2005-03-24
EP1656545A2 (de) 2006-05-17
EP1656545B1 (de) 2012-02-08
EP1656545A4 (de) 2010-06-09
WO2005027037A3 (en) 2005-06-23
JP2007502419A (ja) 2007-02-08
WO2005027037A2 (en) 2005-03-24

Similar Documents

Publication Publication Date Title
WO2007133465A3 (en) A laser illumination system in fluorescent microscopy
Leonard et al. Smartphone-enabled rapid quantification of microplastics
US8110101B2 (en) Method and apparatus for imaging target components in a biological sample using permanent magnets
AU2003219759B2 (en) Methods and algorithms for cell enumeration in a low-cost cytometer
ATE545012T1 (de) VORRICHTUNGEN UND VERFAHREN ZUR ABBILDUNG VON OBJEKTEN MITTELS ßTIME DELAY INTEGRATIONß
US7282180B2 (en) Devices and methods to image objects
WO2020123305A3 (en) Generating capture probes for spatial analysis
WO2004070653A3 (en) Image analysis system and method
IN2012DN05069A (de)
US10241053B2 (en) Bacterial detection platform based on SERS mapping
WO2007035840A3 (en) Methods and systems for image data processing
WO2004006985A3 (en) Assaying and imaging system identifying traits of biological specimens
US20090061477A1 (en) Method and apparatus for imaging target components in a biological sample using permanent magnets
DE60215302D1 (de) Einrichtungen und verfahren für bildobjekte
WO2006014351A3 (en) Exploring fluorophore microenvironments
DK2267427T3 (da) Automatiseret system til bearbejdning af biologiske prøver og fremgangsmåde
WO2010108038A3 (en) A microscopy system and method for creating three dimensional images using probe molecules
WO2011028818A3 (en) High throughput multichannel reader and uses thereof
WO2009076560A3 (en) Method and apparatus for magnetic separation of cells
HUE031851T2 (en) Further development of imaging of immune magnetically enriched rare cells
ATE245278T1 (de) Verfahren zur automatischen analyse von mikroskopaufnahmen
ATE526583T1 (de) Immunomagnetische erfassung und abbildung biologischer zielmoleküle
ATE453872T1 (de) Verfahren und system zum digitalisieren einer probe mit fluoreszenzzielpunkten
MY125801A (en) Inspection method for microorganisms and the like, and unit therefor
JP5333240B2 (ja) 降下煤塵の煤塵種の特定方法