ATE544784T1 - Als cytotoxin geeignetes fusionspolypeptid - Google Patents

Als cytotoxin geeignetes fusionspolypeptid

Info

Publication number
ATE544784T1
ATE544784T1 AT04729841T AT04729841T ATE544784T1 AT E544784 T1 ATE544784 T1 AT E544784T1 AT 04729841 T AT04729841 T AT 04729841T AT 04729841 T AT04729841 T AT 04729841T AT E544784 T1 ATE544784 T1 AT E544784T1
Authority
AT
Austria
Prior art keywords
fusion polypeptides
binding site
cytotoxin
alpha
fusion polypeptide
Prior art date
Application number
AT04729841T
Other languages
English (en)
Inventor
Juerg Nueesch
Jean Rommelaere
Original Assignee
Deutsches Krebsforsch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deutsches Krebsforsch filed Critical Deutsches Krebsforsch
Application granted granted Critical
Publication of ATE544784T1 publication Critical patent/ATE544784T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011Details
    • C12N2750/14011Parvoviridae
    • C12N2750/14311Parvovirus, e.g. minute virus of mice
    • C12N2750/14322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT04729841T 2003-04-30 2004-04-28 Als cytotoxin geeignetes fusionspolypeptid ATE544784T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03009952A EP1473306A1 (de) 2003-04-30 2003-04-30 Als cytotoxin geeignetes fusionspolypeptid
PCT/EP2004/004477 WO2004096858A1 (en) 2003-04-30 2004-04-28 Fusion polypeptide suitable as a cytotoxin

Publications (1)

Publication Number Publication Date
ATE544784T1 true ATE544784T1 (de) 2012-02-15

Family

ID=32981795

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04729841T ATE544784T1 (de) 2003-04-30 2004-04-28 Als cytotoxin geeignetes fusionspolypeptid

Country Status (5)

Country Link
US (2) US20060078970A1 (de)
EP (2) EP1473306A1 (de)
AT (1) ATE544784T1 (de)
ES (1) ES2382036T3 (de)
WO (1) WO2004096858A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1473306A1 (de) * 2003-04-30 2004-11-03 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Als cytotoxin geeignetes fusionspolypeptid

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4472026A (en) 1982-05-06 1984-09-18 At&T Bell Laboratories Electrothermal matrix addressable liquid crystal display
DE3319604A1 (de) 1983-05-30 1984-12-06 Fa. Klaus Reinhold, 4540 Lengerich Kalibriervorrichtung an einem extruder
ATE462791T1 (de) * 1999-08-13 2010-04-15 Deutsches Krebsforsch Parvovirus ns1 varianten
DE60124523T2 (de) * 2001-07-10 2007-09-06 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Zusammensetzung einer Parvovirus VP1-Proteinvariante und eines arvovirus NS1-Proteins zur Induktion von Zytolyse
EP1473306A1 (de) 2003-04-30 2004-11-03 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Als cytotoxin geeignetes fusionspolypeptid

Also Published As

Publication number Publication date
EP1620468A1 (de) 2006-02-01
US20060078970A1 (en) 2006-04-13
US20100144847A1 (en) 2010-06-10
EP1620468B1 (de) 2012-02-08
ES2382036T3 (es) 2012-06-04
EP1473306A1 (de) 2004-11-03
US8598326B2 (en) 2013-12-03
WO2004096858A1 (en) 2004-11-11

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