ATE543915T1 - Zusammensetzungen und verfahren zur bestimmung der empfindlichkeit eines pathogenen virus gegenüber proteaseinhibitoren - Google Patents
Zusammensetzungen und verfahren zur bestimmung der empfindlichkeit eines pathogenen virus gegenüber proteaseinhibitorenInfo
- Publication number
- ATE543915T1 ATE543915T1 AT03742733T AT03742733T ATE543915T1 AT E543915 T1 ATE543915 T1 AT E543915T1 AT 03742733 T AT03742733 T AT 03742733T AT 03742733 T AT03742733 T AT 03742733T AT E543915 T1 ATE543915 T1 AT E543915T1
- Authority
- AT
- Austria
- Prior art keywords
- sensitivity
- compositions
- determining
- methods
- protease inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35717102P | 2002-02-15 | 2002-02-15 | |
US35934202P | 2002-02-22 | 2002-02-22 | |
US39237702P | 2002-06-26 | 2002-06-26 | |
PCT/US2003/004362 WO2003070700A2 (en) | 2002-02-15 | 2003-02-14 | Compositions and methods for determining the susceptibility of a pathogenic virus to protease inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE543915T1 true ATE543915T1 (de) | 2012-02-15 |
Family
ID=27761425
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03742733T ATE543915T1 (de) | 2002-02-15 | 2003-02-14 | Zusammensetzungen und verfahren zur bestimmung der empfindlichkeit eines pathogenen virus gegenüber proteaseinhibitoren |
Country Status (10)
Country | Link |
---|---|
US (1) | US7384734B2 (es) |
EP (1) | EP1483416B1 (es) |
CN (1) | CN1646704A (es) |
AR (1) | AR038557A1 (es) |
AT (1) | ATE543915T1 (es) |
AU (1) | AU2003211026A1 (es) |
CA (1) | CA2476403C (es) |
ES (1) | ES2381866T3 (es) |
TW (1) | TW200303362A (es) |
WO (1) | WO2003070700A2 (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030108857A1 (en) * | 2001-06-04 | 2003-06-12 | Parkin Neil T. | Means and methods for monitoring protease inhibitor antiretroviral therapy and guiding therapeutic decisions in the treatment of HIV/AIDS |
US6869759B1 (en) | 1999-06-22 | 2005-03-22 | Virologic, Inc. | Means and methods for monitoring protease inhibitor antiretroviral therapy and guiding therapeutic decisions in the treatment of HIV/AIDS |
US7186506B1 (en) | 2000-06-12 | 2007-03-06 | Monogram Biosciences, Inc. | Means and methods for monitoring protease inhibitor antiretroviral therapy and guiding therapeutic decisions in the treatment of HIV/AIDS |
US7138231B2 (en) | 2000-09-15 | 2006-11-21 | Monogram Biosciences, Inc. | Means and methods for monitoring protease inhibitor antiretroviral therapy and guiding therapeutic decisions in the treatment of HIV/AIDS |
US7384734B2 (en) | 2002-02-15 | 2008-06-10 | Monogram Biosciences, Inc. | Compositions and methods for determining the susceptibility of a pathogenic virus to protease inhibitors |
CN1678755A (zh) | 2002-07-01 | 2005-10-05 | 瓦罗洛吉克公司 | 确定致病性病毒对蛋白酶抑制剂易感性的组合物和方法 |
CA2491388A1 (en) | 2002-07-01 | 2004-01-08 | Virologic, Inc. | Compositions and methods for determining the susceptibility of a pathogenic virus to protease inhibitors |
US20050148523A1 (en) * | 2003-12-15 | 2005-07-07 | Colonno Richard J. | Method of treating HIV infection in atazanavir-resistant patients using a combination of atazanavir and another protease inhibitor |
WO2007084618A2 (en) * | 2006-01-19 | 2007-07-26 | Monogram Biosciences, Inc. | Method for determining resistance of hiv to protease inhibitor treatment |
EP2121589A2 (en) * | 2006-12-18 | 2009-11-25 | University of Massachusetts | Crystal structures of hiv-1 protease inhibitors bound to hiv-1 protease |
CN101790682B (zh) * | 2007-03-30 | 2016-10-19 | 9898有限公司 | 发展自然产物的药用平台的技术 |
MX2009013461A (es) * | 2007-06-22 | 2010-01-15 | Bristol Myers Squibb Co | Composiciones comprimidas que contienen atazanavir. |
US20100178340A1 (en) * | 2007-06-22 | 2010-07-15 | Bristol-Myers Squibb Company | Tableted compositions containing atazanavir |
AU2008268627A1 (en) * | 2007-06-22 | 2008-12-31 | Bristol-Myers Squibb Company | Tableted compositions containing atazanavir |
SI2170292T1 (sl) * | 2007-06-22 | 2014-05-30 | Bristol-Myers Squibb Holdings Ireland | Tabletirani sestavki, ki vsebujejo atazanavir |
US10480037B2 (en) | 2011-09-23 | 2019-11-19 | Laboratory Corporation Of America Holdings | Methods and systems for predicting HIV-1 coreceptor tropism |
CN103215348B (zh) * | 2013-03-19 | 2015-06-03 | 浙江大学 | Hiv-1病毒蛋白酶抑制剂耐药突变检测试剂盒及方法 |
WO2018096153A1 (en) * | 2016-11-28 | 2018-05-31 | Koninklijke Philips N.V. | Analytic prediction of antibiotic susceptibility |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
EP0361749B1 (en) * | 1988-09-27 | 1995-02-08 | Dana Farber Cancer Institute | A vector comprising a replication competent HIV-I provirus and a heterologous gene |
US5436131A (en) * | 1993-04-02 | 1995-07-25 | Merck & Co., Inc. | Color screening assay for identifying inhibitor resistant HIV protease mutants |
US5766842A (en) * | 1994-09-16 | 1998-06-16 | Sepracor, Inc. | In vitro method for predicting the evolutionary response of a protein to a drug targeted thereagainst |
US6242187B1 (en) * | 1996-01-29 | 2001-06-05 | Virologic, Inc. | Compositions and methods for determining anti-viral drug susceptibility and resistance and anti-viral drug screening |
US5837464A (en) * | 1996-01-29 | 1998-11-17 | Virologic, Inc. | Compositions and methods for determining anti-viral drug susceptibility and resistance and anti-viral drug screening |
US6103462A (en) * | 1998-05-29 | 2000-08-15 | Institut Pasteur | Rapid single-cycle assay for human immunodeficiency virus type-1 drug resistance |
MXPA00012843A (es) | 1998-06-24 | 2002-04-24 | Virologic Inc | Medios y metodo para verificar la terapia antirretroviral con un inhibidor nucleosico de la transcriptasa inversa y guia de decisiones terapeuticas en el tratamiento del vih/sida. |
US7138231B2 (en) * | 2000-09-15 | 2006-11-21 | Monogram Biosciences, Inc. | Means and methods for monitoring protease inhibitor antiretroviral therapy and guiding therapeutic decisions in the treatment of HIV/AIDS |
EP1194587A4 (en) | 1999-06-22 | 2005-07-06 | Virologic Inc | MEANS AND METHODS FOR MONITORING ANTIRETROVIRAL THERAPY USING A PROTEASE INHIBITOR AND FOR ASSISTING THERAPEUTIC DECISIONS ON THE TREATMENT OF HIV / AIDS |
US20030108857A1 (en) * | 2001-06-04 | 2003-06-12 | Parkin Neil T. | Means and methods for monitoring protease inhibitor antiretroviral therapy and guiding therapeutic decisions in the treatment of HIV/AIDS |
WO2002022076A2 (en) | 2000-09-15 | 2002-03-21 | Virologic, Inc. | Means and methods for monitoring protease inhibitor antiretroviral therapy and guiding therapeutic decisions in the treatment of hiv/aids |
EP1407042A4 (en) | 2001-06-04 | 2006-02-22 | Virologic Inc | METHOD AND METHOD FOR MONITORING ANTIRETROVIRAL PROTEASE INHIBITOR THERAPY AND AS A GUIDANCE FOR THERAPEUTIC DECISIONS IN THE TREATMENT OF HIV / AIDS |
US7384734B2 (en) | 2002-02-15 | 2008-06-10 | Monogram Biosciences, Inc. | Compositions and methods for determining the susceptibility of a pathogenic virus to protease inhibitors |
CA2491388A1 (en) * | 2002-07-01 | 2004-01-08 | Virologic, Inc. | Compositions and methods for determining the susceptibility of a pathogenic virus to protease inhibitors |
CN1678755A (zh) | 2002-07-01 | 2005-10-05 | 瓦罗洛吉克公司 | 确定致病性病毒对蛋白酶抑制剂易感性的组合物和方法 |
-
2003
- 2003-02-13 US US10/367,223 patent/US7384734B2/en not_active Expired - Fee Related
- 2003-02-14 TW TW092103100A patent/TW200303362A/zh unknown
- 2003-02-14 ES ES03742733T patent/ES2381866T3/es not_active Expired - Lifetime
- 2003-02-14 CN CN03808382.5A patent/CN1646704A/zh active Pending
- 2003-02-14 EP EP03742733A patent/EP1483416B1/en not_active Expired - Lifetime
- 2003-02-14 AT AT03742733T patent/ATE543915T1/de active
- 2003-02-14 CA CA2476403A patent/CA2476403C/en not_active Expired - Fee Related
- 2003-02-14 WO PCT/US2003/004362 patent/WO2003070700A2/en not_active Application Discontinuation
- 2003-02-14 AU AU2003211026A patent/AU2003211026A1/en not_active Abandoned
- 2003-02-17 AR ARP030100520A patent/AR038557A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
US7384734B2 (en) | 2008-06-10 |
TW200303362A (en) | 2003-09-01 |
EP1483416B1 (en) | 2012-02-01 |
CN1646704A (zh) | 2005-07-27 |
AR038557A1 (es) | 2005-01-19 |
WO2003070700A3 (en) | 2004-02-26 |
CA2476403C (en) | 2012-09-11 |
US20040224307A1 (en) | 2004-11-11 |
AU2003211026A1 (en) | 2003-09-09 |
EP1483416A4 (en) | 2006-09-06 |
CA2476403A1 (en) | 2003-08-28 |
ES2381866T3 (es) | 2012-06-01 |
EP1483416A2 (en) | 2004-12-08 |
WO2003070700A2 (en) | 2003-08-28 |
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