ATE541838T1 - Neue zur synthese von s- und r-omeprazol geeignete verbindungen und ein verfahren zu deren herstellung - Google Patents

Neue zur synthese von s- und r-omeprazol geeignete verbindungen und ein verfahren zu deren herstellung

Info

Publication number
ATE541838T1
ATE541838T1 AT05711081T AT05711081T ATE541838T1 AT E541838 T1 ATE541838 T1 AT E541838T1 AT 05711081 T AT05711081 T AT 05711081T AT 05711081 T AT05711081 T AT 05711081T AT E541838 T1 ATE541838 T1 AT E541838T1
Authority
AT
Austria
Prior art keywords
omeprazole
synthesis
production
new compounds
compounds suitable
Prior art date
Application number
AT05711081T
Other languages
English (en)
Inventor
Christina Fregler
Unge Sverker Von
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE541838T1 publication Critical patent/ATE541838T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT05711081T 2004-02-20 2005-02-17 Neue zur synthese von s- und r-omeprazol geeignete verbindungen und ein verfahren zu deren herstellung ATE541838T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0400410A SE0400410D0 (sv) 2004-02-20 2004-02-20 New compounds
PCT/SE2005/000221 WO2005080374A1 (en) 2004-02-20 2005-02-17 New compounds useful for the synthesis of s- and r-omeprazole and a process for their preparation

Publications (1)

Publication Number Publication Date
ATE541838T1 true ATE541838T1 (de) 2012-02-15

Family

ID=31989582

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05711081T ATE541838T1 (de) 2004-02-20 2005-02-17 Neue zur synthese von s- und r-omeprazol geeignete verbindungen und ein verfahren zu deren herstellung

Country Status (9)

Country Link
US (4) US20050187256A1 (de)
EP (1) EP1718636B1 (de)
JP (1) JP2007523160A (de)
AT (1) ATE541838T1 (de)
CA (1) CA2553877C (de)
ES (1) ES2378237T3 (de)
HK (1) HK1098474A1 (de)
SE (1) SE0400410D0 (de)
WO (1) WO2005080374A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0400410D0 (sv) * 2004-02-20 2004-02-20 Astrazeneca Ab New compounds
WO2007088559A1 (en) * 2006-02-01 2007-08-09 Jubilant Organosys Limited Process for producing substituted sulphoxides
US7579476B2 (en) * 2006-02-24 2009-08-25 Praktikatalyst Pharma, Llc Transition metal mediated oxidation of hetero atoms in organic molecules coordinated to transition metals
EP2203441A4 (de) * 2007-10-03 2012-02-15 Ipca Lab Ltd Verfahren für optisch aktive sulfoxidverbindungen
US20110178072A1 (en) * 2008-07-23 2011-07-21 Vadim Gladyshev Stereospecificity of methylsulfinyl reduction
CN108484578B (zh) * 2018-04-09 2019-03-26 珠海润都制药股份有限公司 一种艾司奥美拉唑杂质制备的方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
SE8301182D0 (sv) 1983-03-04 1983-03-04 Haessle Ab Novel compounds
ES2026761A6 (es) 1990-10-31 1992-05-01 Genesis Para La Investigacion Procedimiento de obtencion del omeprazol.
DE4035455A1 (de) 1990-11-08 1992-05-14 Byk Gulden Lomberg Chem Fab Enantiomerentrennung
SE9301830D0 (sv) 1993-05-28 1993-05-28 Ab Astra New compounds
SE504459C2 (sv) 1994-07-15 1997-02-17 Astra Ab Förfarande för framställning av substituerade sulfoxider
HRP960232A2 (en) * 1995-07-03 1998-02-28 Astra Ab A process for the optical purification of compounds
TW385306B (en) * 1996-11-14 2000-03-21 Takeda Chemical Industries Ltd Method for producing crystals of benzimidazole derivatives
SE510666C2 (sv) 1996-12-20 1999-06-14 Astra Ab Nya Kristallmodifikationer
EP0968204A1 (de) * 1997-03-07 2000-01-05 A/S GEA Farmaceutisk Fabrik Verfahren zur herstellung von 2-[[(2-pyridinyl)methyl]sulfinyl]-1h-benzimidazolen und dabei verwendbare neue verbindungen
WO1998040378A1 (en) 1997-03-07 1998-09-17 A/S Gea Farmaceutisk Fabrik Process for the preparation of 2-[[(2-pyridinyl)methyl]sulfinyl]-1h-benzimidazoles and novel compounds of use for such purpose
US6303787B1 (en) * 1998-05-27 2001-10-16 Natco Pharma Limited Intermediates and an improved process for the preparation of Omeprazole employing the said intermediates
ES2166269B1 (es) * 1999-07-14 2003-04-01 Sint Quimica Sa Nuevo procedimiento de obtencion de derivados de 2-(2-piridinilmetilsulfinil)-1h-benzimidazol.
PT102361B (pt) 1999-09-22 2002-07-31 Herbex Produtos Quimicos Lda Metodo de obrencao de arileteres e tioeteres utilizando radiacao micro-ondas
KR100775802B1 (ko) * 2000-04-28 2007-11-12 다케다 야쿠힌 고교 가부시키가이샤 광학 활성 술폭시드 유도체의 제조 방법
AU2001256732A1 (en) * 2000-05-15 2001-11-26 Takeda Chemical Industries Ltd. Process for producing crystal
AU2000258410A1 (en) * 2000-07-28 2003-12-02 Herbex, Produtos Quimicos, Sa New method for the preparation of the anti-ulcer compounds omeprazole, lansoprazole and pantoprazole
ES2187248B1 (es) 2000-08-25 2004-01-16 Sint Quimica Sa Nuevo procedimiento de obtencion de derivados de 2-(2-piridinilmetilsulfinil)-1h-benzimidazol.
WO2003089408A2 (en) * 2002-04-22 2003-10-30 Sun Pharmaceutical Industries Limited Optically active substituted pyridinylmethyl-sulphinyl-benzimidazole and salts
AU2003288703A1 (en) 2003-12-05 2005-06-24 Hetero Drugs Limited A process for the preparation of substitited pyridinylmethylsulfinyl- benzimidazole enantiomers
SE0400410D0 (sv) 2004-02-20 2004-02-20 Astrazeneca Ab New compounds

Also Published As

Publication number Publication date
EP1718636A1 (de) 2006-11-08
JP2007523160A (ja) 2007-08-16
HK1098474A1 (en) 2007-07-20
WO2005080374A1 (en) 2005-09-01
US20070161682A1 (en) 2007-07-12
US20050187256A1 (en) 2005-08-25
SE0400410D0 (sv) 2004-02-20
CA2553877C (en) 2012-07-31
ES2378237T3 (es) 2012-04-10
EP1718636B1 (de) 2012-01-18
US20080255199A1 (en) 2008-10-16
US20090253911A1 (en) 2009-10-08
CA2553877A1 (en) 2005-09-01
US8697880B2 (en) 2014-04-15

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