ATE541036T1 - Verfahren zur überexpression zwitterionischer polysaccharide - Google Patents

Verfahren zur überexpression zwitterionischer polysaccharide

Info

Publication number
ATE541036T1
ATE541036T1 AT03714135T AT03714135T ATE541036T1 AT E541036 T1 ATE541036 T1 AT E541036T1 AT 03714135 T AT03714135 T AT 03714135T AT 03714135 T AT03714135 T AT 03714135T AT E541036 T1 ATE541036 T1 AT E541036T1
Authority
AT
Austria
Prior art keywords
overexpressing
compositions
directed
capsular
polysaccharides
Prior art date
Application number
AT03714135T
Other languages
German (de)
English (en)
Inventor
Laurie Comstock
Katja Weinacht
Michael Coyne
Denis Kasper
Arthur Tzianabos
Original Assignee
Brigham & Womens Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham & Womens Hospital filed Critical Brigham & Womens Hospital
Application granted granted Critical
Publication of ATE541036T1 publication Critical patent/ATE541036T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
AT03714135T 2002-03-13 2003-03-13 Verfahren zur überexpression zwitterionischer polysaccharide ATE541036T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36416802P 2002-03-13 2002-03-13
PCT/US2003/007775 WO2003077863A2 (en) 2002-03-13 2003-03-13 Method for overexpression of zwitterionic polysaccharides

Publications (1)

Publication Number Publication Date
ATE541036T1 true ATE541036T1 (de) 2012-01-15

Family

ID=28041884

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03714135T ATE541036T1 (de) 2002-03-13 2003-03-13 Verfahren zur überexpression zwitterionischer polysaccharide

Country Status (7)

Country Link
US (4) US7166455B2 (https=)
EP (1) EP1483384B1 (https=)
JP (1) JP4733349B2 (https=)
AT (1) ATE541036T1 (https=)
AU (2) AU2003218144B2 (https=)
CA (1) CA2479246C (https=)
WO (1) WO2003077863A2 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7083777B1 (en) * 1999-04-02 2006-08-01 The Brigham And Women's Hospital, Inc. Immunomodulating polymers
SV2003000753A (es) 2000-12-05 2003-06-16 Brigham & Womens Hospital Uso de polisacaridos zwitterionicos para la especifica modulacion del progreso inmunologico
CA2479246C (en) * 2002-03-13 2017-05-09 Laurie E. Comstock Method for overexpression of zwitterionic polysaccharides
CA2520865A1 (en) 2003-03-31 2004-10-21 The Brigham And Women's Hospital, Inc. Zwitterionic immunomodulators for the treatment of asthma and allergy
CN1886427B (zh) 2003-11-28 2012-05-23 伊士曼化工公司 纤维素共聚体和氧化方法
WO2007092451A2 (en) * 2006-02-06 2007-08-16 The Brigham And Women's Hospital, Inc. Zwitterionic polysaccharides for promotion of immune system maturation and health
EP2217250A4 (en) * 2007-11-09 2011-01-05 California Inst Of Techn IMMUNOMODULATING COMPOUNDS AND RELEVANT COMPOSITIONS AND METHODS
US20110002965A1 (en) * 2007-11-09 2011-01-06 Round June L Immunomodulating compounds and related compositions and methods
US20100311686A1 (en) * 2009-06-03 2010-12-09 Kasper Lloyd H Nutraceutical composition and methods for preventing or treating multiple sclerosis
US8580278B2 (en) 2009-06-03 2013-11-12 Trustees Of Dartmouth College Nutraceutical composition and methods for preventing or treating multiple sclerosis
WO2011127302A2 (en) 2010-04-07 2011-10-13 Yue Shen Vehicle for delivering a compound to a mucous membrane and related compositions, methods and systems
US20110287048A1 (en) 2010-05-20 2011-11-24 Round June L Antigen Specific Tregs and related compositions, methods and systems
EP2731617A4 (en) 2011-07-12 2015-07-01 Brigham & Womens Hospital LIPID-BASED PSA COMPOSITIONS, METHOD FOR THEIR INSULATION AND USE METHOD THEREFOR
EP2764090B1 (en) * 2011-10-03 2017-12-13 California Institute of Technology Generation of psa-only producing mutant strain
JP2016521284A (ja) 2013-05-10 2016-07-21 カリフォルニア インスティチュート オブ テクノロジー 大腸ガンのプロバイオティクスによる防止および処置
WO2016201342A1 (en) 2015-06-10 2016-12-15 California Institute Of Technology Sepsis treatment and related compositions methods and systems
JP6918365B2 (ja) * 2015-08-19 2021-08-11 プレジデント アンド フェローズ オブ ハーバード カレッジ 脂質化ｐｓａ組成物および方法
EP3484441A4 (en) 2016-07-15 2020-03-18 President and Fellows of Harvard College GLYCOLIPID COMPOSITIONS AND METHOD FOR USE

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987005932A1 (en) 1986-03-26 1987-10-08 Genexpress Aps Biological containment
JPS618945A (ja) 1984-06-25 1986-01-16 Nec Corp 半導体集積回路装置
US4952524A (en) 1989-05-05 1990-08-28 At&T Bell Laboratories Semiconductor device manufacture including trench formation
KR940006696B1 (ko) 1991-01-16 1994-07-25 금성일렉트론 주식회사 반도체 소자의 격리막 형성방법
US5350941A (en) 1992-09-23 1994-09-27 Texas Instruments Incorporated Trench isolation structure having a trench formed in a LOCOS structure and a channel stop region on the sidewalls of the trench
US5433794A (en) 1992-12-10 1995-07-18 Micron Technology, Inc. Spacers used to form isolation trenches with improved corners
JPH07326664A (ja) 1994-05-31 1995-12-12 Fuji Electric Co Ltd ウエハの誘電体分離溝の充填方法
US5700787A (en) * 1994-09-02 1997-12-23 Brigham & Women's Hospital, Inc. Capsular polysaccharide immunomodulator
US5679654A (en) 1994-09-02 1997-10-21 Brigham & Women's Hospital, Inc. Capsular polysaccharide immunomodulator
US5851808A (en) 1997-02-28 1998-12-22 Baylor College Of Medicine Rapid subcloning using site-specific recombination
US7083777B1 (en) 1999-04-02 2006-08-01 The Brigham And Women's Hospital, Inc. Immunomodulating polymers
AUPQ899700A0 (en) 2000-07-25 2000-08-17 Borody, Thomas Julius Probiotic recolonisation therapy
SV2003000753A (es) 2000-12-05 2003-06-16 Brigham & Womens Hospital Uso de polisacaridos zwitterionicos para la especifica modulacion del progreso inmunologico
CA2479246C (en) * 2002-03-13 2017-05-09 Laurie E. Comstock Method for overexpression of zwitterionic polysaccharides
CA2520865A1 (en) 2003-03-31 2004-10-21 The Brigham And Women's Hospital, Inc. Zwitterionic immunomodulators for the treatment of asthma and allergy

Also Published As

Publication number Publication date
US20030219413A1 (en) 2003-11-27
CA2479246C (en) 2017-05-09
US20070154991A1 (en) 2007-07-05
EP1483384A2 (en) 2004-12-08
AU2003218144A1 (en) 2003-09-29
US7678558B2 (en) 2010-03-16
AU2008243143A1 (en) 2008-11-27
AU2003218144B2 (en) 2008-08-14
JP4733349B2 (ja) 2011-07-27
CA2479246A1 (en) 2003-09-25
US20070020730A1 (en) 2007-01-25
AU2008243143B2 (en) 2012-10-04
WO2003077863A2 (en) 2003-09-25
US7803602B2 (en) 2010-09-28
WO2003077863A3 (en) 2004-07-22
EP1483384A4 (en) 2006-11-02
US7166455B2 (en) 2007-01-23
JP2005519617A (ja) 2005-07-07
US20080057565A1 (en) 2008-03-06
EP1483384B1 (en) 2012-01-11

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