ATE540675T1 - Verbindungen zur behandlung von stoffwechselstörungen - Google Patents

Verbindungen zur behandlung von stoffwechselstörungen

Info

Publication number
ATE540675T1
ATE540675T1 AT06784338T AT06784338T ATE540675T1 AT E540675 T1 ATE540675 T1 AT E540675T1 AT 06784338 T AT06784338 T AT 06784338T AT 06784338 T AT06784338 T AT 06784338T AT E540675 T1 ATE540675 T1 AT E540675T1
Authority
AT
Austria
Prior art keywords
carbon atoms
ring
alkyl
hydrogen
treatment
Prior art date
Application number
AT06784338T
Other languages
English (en)
Inventor
Shalini Sharma
Borstel Reid Von
Original Assignee
Wellstat Therapeutics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellstat Therapeutics Corp filed Critical Wellstat Therapeutics Corp
Application granted granted Critical
Publication of ATE540675T1 publication Critical patent/ATE540675T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT06784338T 2005-04-01 2006-03-31 Verbindungen zur behandlung von stoffwechselstörungen ATE540675T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66745705P 2005-04-01 2005-04-01
PCT/US2006/012050 WO2006127133A2 (en) 2005-04-01 2006-03-31 Compounds for the treatment of metabolic disorders

Publications (1)

Publication Number Publication Date
ATE540675T1 true ATE540675T1 (de) 2012-01-15

Family

ID=37452522

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06784338T ATE540675T1 (de) 2005-04-01 2006-03-31 Verbindungen zur behandlung von stoffwechselstörungen

Country Status (5)

Country Link
US (1) US8022249B2 (de)
EP (1) EP1868595B1 (de)
AT (1) ATE540675T1 (de)
CA (1) CA2602854C (de)
WO (1) WO2006127133A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU230352B1 (hu) 2001-06-12 2016-02-29 Wellstat Therapeutics Corporation Metabolikus rendellenességek kezelésére adható vegyületek és ezeket tartalmazó gyógyászati készítmények
EP1556085A4 (de) 2002-11-01 2012-08-22 Wellstat Therapeutics Corp Verbindungen zur behandlung von stoffwechselst rungen
EP1601251B1 (de) * 2003-02-13 2014-11-12 Wellstat Therapeutics Corporation Verbindungen zur behandlung von stoffwechselstörungen
CN1774244A (zh) 2003-04-15 2006-05-17 维尔斯达医疗公司 用于治疗代谢紊乱的化合物
KR20080106455A (ko) * 2006-03-31 2008-12-05 웰스태트 테러퓨틱스 코포레이션 대사장애의 조합치료
WO2007137008A2 (en) 2006-05-18 2007-11-29 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
CA2661293A1 (en) * 2006-08-17 2008-02-21 Wellstat Therapeutics Corporation Combination treatment for metabolic disorders
GB0813403D0 (en) * 2008-07-22 2008-08-27 Lectus Therapeutics Ltd Potassium ion channel modulators & uses thereof
JP7080812B2 (ja) 2015-10-27 2022-06-06 アセチロン ファーマシューティカルズ インコーポレイテッド 糖尿病性末梢神経障害の治療のためのｈｄａｃ阻害剤

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR5035M (de) 1964-07-28 1967-05-02
US4053607A (en) * 1972-04-04 1977-10-11 Beecham Group Limited Aryloxypyridine for treating hyperglycaemia
US4067892A (en) * 1973-08-23 1978-01-10 Beecham Group Limited Substituted (4-carboxyphenoxy) phenyl alkane compounds
GB1488330A (en) 1973-12-19 1977-10-12 Smith Kline French Lab Dihydropyridazinones
JPS5225734A (en) 1975-08-23 1977-02-25 Kyorin Pharmaceut Co Ltd Process for preparation of 4-(4'-halogenobenzyloxy)-bonzoyl acetate
NL7614113A (nl) * 1976-12-18 1978-06-20 Akzo Nv Hydroxamzuren.
JPS56115747A (en) 1980-02-19 1981-09-11 Nippon Synthetic Chem Ind Co Ltd:The 2- 2-hydroxyethylamino -3-substituted benzoylpropionic acid, its preparation and germicide
JPS57149254A (en) * 1981-03-10 1982-09-14 Hodogaya Chem Co Ltd M-benzyloxybenzamide derivative and herbicide containing the same
JPH01216961A (ja) * 1988-02-25 1989-08-30 Takeda Chem Ind Ltd １２−リポキシゲネース阻害剤
US5484926A (en) 1993-10-07 1996-01-16 Agouron Pharmaceuticals, Inc. HIV protease inhibitors
GB9315595D0 (en) 1993-07-28 1993-09-08 Res Inst Medicine Chem New compounds
GB9404485D0 (en) * 1994-03-09 1994-04-20 Cancer Res Campaign Tech Benzamide analogues
WO1996028423A1 (fr) 1995-03-15 1996-09-19 Sankyo Company, Limited Composes dipeptidiques de structure ahpba
HU230352B1 (hu) * 2001-06-12 2016-02-29 Wellstat Therapeutics Corporation Metabolikus rendellenességek kezelésére adható vegyületek és ezeket tartalmazó gyógyászati készítmények
US6951884B2 (en) * 2002-06-12 2005-10-04 Hoffmann-La Roche Inc. Fluorobenzamides and uses thereof
US6900354B2 (en) 2002-07-15 2005-05-31 Hoffman-La Roche Inc. 3-phenyl-propionamido, 3-phenyl-acrylamido and 3-phenyl-propynamido derivatives
EP1556085A4 (de) * 2002-11-01 2012-08-22 Wellstat Therapeutics Corp Verbindungen zur behandlung von stoffwechselst rungen
EP1601251B1 (de) * 2003-02-13 2014-11-12 Wellstat Therapeutics Corporation Verbindungen zur behandlung von stoffwechselstörungen
CN1774244A (zh) 2003-04-15 2006-05-17 维尔斯达医疗公司 用于治疗代谢紊乱的化合物
WO2004093806A2 (en) * 2003-04-22 2004-11-04 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
EP1617835B1 (de) * 2003-04-30 2011-09-28 Wellstat Therapeutics Corporation Verbindungen zur behandlung von stoffwechselstörungen
AU2004266673B2 (en) * 2003-08-20 2010-08-05 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
KR20080106455A (ko) 2006-03-31 2008-12-05 웰스태트 테러퓨틱스 코포레이션 대사장애의 조합치료
CA2661293A1 (en) 2006-08-17 2008-02-21 Wellstat Therapeutics Corporation Combination treatment for metabolic disorders

Also Published As

Publication number Publication date
WO2006127133A2 (en) 2006-11-30
WO2006127133B1 (en) 2007-03-29
EP1868595A2 (de) 2007-12-26
CA2602854C (en) 2013-05-14
CA2602854A1 (en) 2006-11-30
EP1868595B1 (de) 2012-01-11
US8022249B2 (en) 2011-09-20
US20090234016A1 (en) 2009-09-17
WO2006127133A3 (en) 2007-02-01
EP1868595A4 (de) 2010-06-09

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