ATE53591T1 - Verfahren zur reinigung von gamma-interferon. - Google Patents
Verfahren zur reinigung von gamma-interferon.Info
- Publication number
- ATE53591T1 ATE53591T1 AT85400190T AT85400190T ATE53591T1 AT E53591 T1 ATE53591 T1 AT E53591T1 AT 85400190 T AT85400190 T AT 85400190T AT 85400190 T AT85400190 T AT 85400190T AT E53591 T1 ATE53591 T1 AT E53591T1
- Authority
- AT
- Austria
- Prior art keywords
- interferon
- gamma
- solution
- gamma interferon
- activity
- Prior art date
Links
- 102000008070 Interferon-gamma Human genes 0.000 title abstract 5
- 108010074328 Interferon-gamma Proteins 0.000 title abstract 5
- 229940044627 gamma-interferon Drugs 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 4
- 230000000694 effects Effects 0.000 abstract 2
- 239000000243 solution Substances 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000003929 acidic solution Substances 0.000 abstract 1
- 238000001042 affinity chromatography Methods 0.000 abstract 1
- 238000010828 elution Methods 0.000 abstract 1
- 230000007420 reactivation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/249—Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/57—IFN-gamma
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/811—Interferon
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
- Y10S530/809—Fused cells, e.g. hybridoma
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/829—Blood
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/577,908 US4499014A (en) | 1984-02-07 | 1984-02-07 | Method for purifying gamma-interferon |
| EP85400190A EP0152346B1 (de) | 1984-02-07 | 1985-02-05 | Verfahren zur Reinigung von gamma-Interferon |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE53591T1 true ATE53591T1 (de) | 1990-06-15 |
Family
ID=24310633
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85400190T ATE53591T1 (de) | 1984-02-07 | 1985-02-05 | Verfahren zur reinigung von gamma-interferon. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4499014A (de) |
| EP (1) | EP0152346B1 (de) |
| JP (1) | JPS6187698A (de) |
| AT (1) | ATE53591T1 (de) |
| CA (1) | CA1237669A (de) |
| DE (1) | DE3578181D1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4789631A (en) * | 1984-02-17 | 1988-12-06 | Synbiotics Corporation | Immunoassay for anti-dirofilaria immitis antibody |
| FR2560212B1 (fr) * | 1984-02-24 | 1989-12-29 | Unicet | Anticorps monoclonaux contre l'interferon a2 et hybridomes produisant de tels anticorps |
| US4743560A (en) * | 1984-03-26 | 1988-05-10 | Becton Dickinson And Company | Solid phase assay |
| NL8501682A (nl) * | 1985-06-11 | 1987-01-02 | Tno | Nieuw, uit bloed geisoleerd eiwit, werkwijze ter bereiding van dit eiwit, antilichamen tegen het nieuwe eiwit en farmaceutische preparaten, die het eiwit of de antilichamen bevatten. |
| NZ212523A (en) * | 1985-06-24 | 1989-01-06 | Univ Massey | Mobile phase for purification of proteins by high performance liquid chromatography |
| FR2584418B1 (fr) * | 1985-07-05 | 1988-11-10 | Unicet Laboratoires | Anticorps monoclonaux contre le g-interferon, hybridomes produisant de tels anticorps, procede de preparation de tels anticorps et de tels hybridomes, leur utilisation pour differencier les gifs, et ensemble ou " kit " utilisant de tels anticorps |
| DK580789D0 (da) * | 1989-11-20 | 1989-11-20 | Novo Nordisk As | Fremgangsmaade til oprensning af polypeptider |
| US7045333B1 (en) * | 1998-01-16 | 2006-05-16 | Incyte Corporation | Human protease molecules |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4184917A (en) * | 1974-04-01 | 1980-01-22 | Sandoz Ltd. | Process for producing a structurally modified interferon |
| NL7404590A (nl) * | 1974-04-03 | 1975-10-07 | Stichting Rega V Z W | Werkwijze voor het reactiveren van interferon. |
| FR2351665A1 (fr) * | 1976-05-21 | 1977-12-16 | Elf Aquitaine | Procede de purification de preparations possedant notamment une activite interferon, preparations purifiees ainsi obtenues et leur application en tant que medicament |
| DK485977A (da) * | 1977-11-01 | 1979-05-02 | Ess Foodeksport | Fremgangsmaade til udvinding af et biologisk aktivt materiale fra svineblodfraktioner |
| IN150740B (de) * | 1978-11-24 | 1982-12-04 | Hoffmann La Roche | |
| JPS55154919A (en) * | 1979-05-24 | 1980-12-02 | Hayashibara Takeshi | Preparation of interferon |
| US4289689A (en) * | 1980-03-14 | 1981-09-15 | Hoffmann-La Roche Inc. | Preparation of homogeneous human fibroblast interferon |
| JPS5651995A (en) * | 1979-10-05 | 1981-05-09 | Green Cross Corp:The | Preparation of interferon |
| US4252791A (en) * | 1979-10-19 | 1981-02-24 | The Medical College Of Wisconsin, Inc. | Interferon stabilization |
| NL7907791A (nl) * | 1979-10-23 | 1981-04-27 | Stichting Rega V Z W | Werkwijze voor het zuiveren van interferon. |
| US4440675A (en) * | 1981-08-18 | 1984-04-03 | Meloy Laboratories, Inc. | Human immune interferon |
| WO1984002129A1 (fr) * | 1982-11-22 | 1984-06-07 | Takeda Chemical Industries Ltd | Proteine de l'interferon immun humain et son procede de preparation |
| US4432895A (en) * | 1982-11-24 | 1984-02-21 | Hoffmann-La Roche Inc. | Monomeric interferons |
| US4485017A (en) * | 1982-12-22 | 1984-11-27 | Cetus Corporation | Isolation of human interferon by immunosorbent and high performance liquid chromatography |
-
1984
- 1984-02-07 US US06/577,908 patent/US4499014A/en not_active Expired - Fee Related
- 1984-12-07 CA CA000469662A patent/CA1237669A/en not_active Expired
-
1985
- 1985-01-17 JP JP60006657A patent/JPS6187698A/ja active Granted
- 1985-02-05 DE DE8585400190T patent/DE3578181D1/de not_active Expired - Lifetime
- 1985-02-05 AT AT85400190T patent/ATE53591T1/de active
- 1985-02-05 EP EP85400190A patent/EP0152346B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA1237669A (en) | 1988-06-07 |
| EP0152346B1 (de) | 1990-06-13 |
| US4499014A (en) | 1985-02-12 |
| JPS6187698A (ja) | 1986-05-06 |
| EP0152346A3 (en) | 1986-09-10 |
| EP0152346A2 (de) | 1985-08-21 |
| DE3578181D1 (de) | 1990-07-19 |
| JPH0566400B2 (de) | 1993-09-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3585147D1 (de) | Verfahren zur reinigung von proteinen. | |
| NZ213985A (en) | Method of purifying bovine lactoferrin | |
| YU45871B (sh) | Polipeptid sa humanim imunointerferonskim (ifn-gama) svojstvima | |
| FR2603581B1 (fr) | Procede pour isoler et purifier des aminoacides par chromatographie | |
| YU47735B (sh) | Postupak za sintezu biološki aktivnih polipeptida limfotoksina | |
| DE3671936D1 (de) | Verfahren zur oxidation von in russfiltersystemen abgelagertem russ. | |
| DE3880425D1 (de) | Verfahren zur mikrobiologischen umwandlung von schwefelhaltigen schadstoffen in abgasen. | |
| DK0620709T3 (da) | Fremgangsmåde til isolering af lactoferrin og lactoperoxidase fra mælk og mælkeprodukter | |
| DK564585A (da) | Immobiliseret antistofsystem og fremgangsmaade til dets fremstilling | |
| DE3677685D1 (de) | Signalkodierungsverfahren und zur ausfuehrung dieses verfahrens. | |
| ATE113960T1 (de) | Proteingewinnung. | |
| EP0208215A3 (en) | Purification of blood clotting factors and other blood proteins on non-carbohydrate sulfated matrices | |
| FI864267A7 (fi) | Modifioitu menetelmä SiO2:n puhdistamiseksi lähekkäisiksi jakeiksi jaettuina erinä. | |
| GB1534812A (en) | Method for the purification of interferon | |
| DE3583439D1 (de) | Verfahren zur heizung von zu verbindenden metallelementen. | |
| FI850778A7 (fi) | Menetelmä NO x-pitoisuuden alentamiseksi pyörrekerrospolttolaitteissa. | |
| ATE53591T1 (de) | Verfahren zur reinigung von gamma-interferon. | |
| ATE47883T1 (de) | Verfahren zur selektiven erhoehung des anteiles von einzelnen hauptkomponenten des teicoplanin a2-komplexes. | |
| DE3576362D1 (de) | Verfahren zur reinigung einer physiologisch aktiven substanz, die durch rekombinante dna-technik hergestellt wurde. | |
| ES521030A0 (es) | Metodo de preparar aminoaminoacidos y analogos. | |
| ATE71110T1 (de) | Verfahren zur reinigung eines proteins. | |
| EP0188262A3 (de) | Verfahren zur Isolierung von Hühnereiweisscystatin, antivirale Agenzien die sie enthalten und seine Verwendung als viraler Protease-Inhibitor | |
| DE3681201D1 (de) | Verfahren zur verbesserten und dauerhaften haftung an metall. | |
| ATE47536T1 (de) | Fluid-crack-katalysator und verfahren zur herstellung. | |
| FI850936A7 (fi) | Immobilisoitu entsyymikoostumus ja menetelmä sen valmistamiseksi. |