ATE53299T1 - Blutstillende irrigationsloesung. - Google Patents
Blutstillende irrigationsloesung.Info
- Publication number
- ATE53299T1 ATE53299T1 AT86305933T AT86305933T ATE53299T1 AT E53299 T1 ATE53299 T1 AT E53299T1 AT 86305933 T AT86305933 T AT 86305933T AT 86305933 T AT86305933 T AT 86305933T AT E53299 T1 ATE53299 T1 AT E53299T1
- Authority
- AT
- Austria
- Prior art keywords
- solution
- hemostatic
- irrigation solution
- protamine
- norepinephrine
- Prior art date
Links
- 230000002439 hemostatic effect Effects 0.000 title 1
- 229940113601 irrigation solution Drugs 0.000 title 1
- SFLSHLFXELFNJZ-QMMMGPOBSA-N (-)-norepinephrine Chemical compound NC[C@H](O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-QMMMGPOBSA-N 0.000 abstract 1
- SLXKOJJOQWFEFD-UHFFFAOYSA-N 6-aminohexanoic acid Chemical compound NCCCCCC(O)=O SLXKOJJOQWFEFD-UHFFFAOYSA-N 0.000 abstract 1
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 abstract 1
- 102000007327 Protamines Human genes 0.000 abstract 1
- 108010007568 Protamines Proteins 0.000 abstract 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 1
- 108090000190 Thrombin Proteins 0.000 abstract 1
- 229960002684 aminocaproic acid Drugs 0.000 abstract 1
- 239000001110 calcium chloride Substances 0.000 abstract 1
- 229910001628 calcium chloride Inorganic materials 0.000 abstract 1
- 229960002713 calcium chloride Drugs 0.000 abstract 1
- 230000015271 coagulation Effects 0.000 abstract 1
- 238000005345 coagulation Methods 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229960002748 norepinephrine Drugs 0.000 abstract 1
- SFLSHLFXELFNJZ-UHFFFAOYSA-N norepinephrine Natural products NCC(O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-UHFFFAOYSA-N 0.000 abstract 1
- 229940048914 protamine Drugs 0.000 abstract 1
- 229960004072 thrombin Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4833—Thrombin (3.4.21.5)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/763,056 US4637815A (en) | 1985-08-06 | 1985-08-06 | Irrigational hemostatic solution |
| EP86305933A EP0211629B1 (de) | 1985-08-06 | 1986-08-01 | Blutstillende Irrigationslösung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE53299T1 true ATE53299T1 (de) | 1990-06-15 |
Family
ID=25066769
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86305933T ATE53299T1 (de) | 1985-08-06 | 1986-08-01 | Blutstillende irrigationsloesung. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4637815A (de) |
| EP (1) | EP0211629B1 (de) |
| JP (1) | JPS6259222A (de) |
| AT (1) | ATE53299T1 (de) |
| DE (1) | DE3671700D1 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5053006A (en) * | 1988-04-19 | 1991-10-01 | Watson Brant D | Method for the permanent occlusion of arteries |
| EP0365705A1 (de) * | 1988-10-26 | 1990-05-02 | Zentralna Problemna Laboratoria Po Kryobiologia I Lyophilisazia | Biopräparat zur Behandlung von Wunden |
| US5171217A (en) * | 1991-02-28 | 1992-12-15 | Indiana University Foundation | Method for delivery of smooth muscle cell inhibitors |
| DE69433939T2 (de) * | 1993-11-03 | 2005-08-11 | Clarion Pharmaceuticals, Inc., Madison | Hämostatisches pflaster |
| US5681278A (en) * | 1994-06-23 | 1997-10-28 | Cormedics Corp. | Coronary vasculature treatment method |
| KR100517210B1 (ko) * | 1994-12-12 | 2006-06-07 | 오메로스 코포레이션 | 통증,염증및경련억제용관주용액 |
| JPH10510540A (ja) * | 1994-12-12 | 1998-10-13 | オメロス メディカル システムズ，インコーポレーテッド | 灌注用溶液並びに疼痛、炎症及びけいれんの抑制法 |
| EP2301562B1 (de) * | 1994-12-12 | 2013-04-17 | Omeros Corporation | Bespülungslösung und deren Verwendung zur perioperativen Hemmung von Schmerzen, Entzündungen und/oder Spasmen |
| AU5638096A (en) * | 1995-06-07 | 1996-12-30 | Clarion Pharmaceuticals, Inc. | Non-biological patch for hemostasis |
| DE10258954A1 (de) * | 2002-12-16 | 2004-07-08 | Langer, Hans-Georg | Blutungsstillende Wundversorgung |
| EP2308469A1 (de) * | 2005-05-18 | 2011-04-13 | Pulmatrix, Inc. | Formulierung zur Änderung der biophysikalischen Eigenschaften von Mukosa |
| EP1888049A2 (de) * | 2005-05-25 | 2008-02-20 | The Massachusetts Institute Of Technology | Lokalisierte zuführung von inotropen herzmitteln |
| US8057426B2 (en) * | 2007-01-03 | 2011-11-15 | Medtronic Vascular, Inc. | Devices and methods for injection of multiple-component therapies |
| EP2207537B1 (de) * | 2007-10-02 | 2017-06-14 | Fremont Group Ltd | Systemische hämostasefördernde wirkung von sympathikomimetika mit agonistischen wirkungen auf die alpha-adrenergen und/oder beta-adrenergen rezeptoren des sympathischen nervensystems im zusammenhang mit verbesserter gerinnselstärke |
| US8562586B2 (en) * | 2008-08-26 | 2013-10-22 | Massachusetts Institute Of Technology | Devices and systems for local delivery of inotropic agents to the epicardium |
| WO2010111644A1 (en) * | 2009-03-26 | 2010-09-30 | Pulmatrix, Inc. | Pharmaceutical formulations and methods for treating respiratory tract infections |
| CN102497853B (zh) | 2009-03-26 | 2018-03-23 | 普马特里克斯营业公司 | 治疗肺病的干粉配方与方法 |
| WO2012030647A1 (en) | 2010-08-30 | 2012-03-08 | Pulmatrix, Inc. | Treatment of cystic fibrosis using calcium lactate, leucine and sodium chloride in a respiraple dry powder |
| JP5877201B2 (ja) | 2010-08-30 | 2016-03-02 | パルマトリックス，インコーポレイテッド | 肺疾患を治療するための乾燥粉末製剤および方法 |
| ES2710537T3 (es) | 2010-09-29 | 2019-04-25 | Pulmatrix Operating Co Inc | Polvos secos catiónicos |
| EP4008326A1 (de) | 2010-09-29 | 2022-06-08 | Pulmatrix Operating Company, Inc. | Einwertige metallkationen-trockenpulver zum inhalieren |
| CN109999013A (zh) | 2012-02-29 | 2019-07-12 | 普马特里克斯营业公司 | 可吸入干粉剂 |
| HK1221175A1 (zh) | 2013-04-01 | 2017-05-26 | Pulmatrix Operating Company, Inc. | 噻托溴铵乾粉 |
| JP6862441B2 (ja) * | 2015-11-08 | 2021-04-21 | オムリックス・バイオファーマシューティカルズ・リミテッドＯｍｒｉｘ Ｂｉｏｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ． | セルロース系短尺繊維及び長尺繊維の止血混合物 |
| RU2741304C2 (ru) * | 2015-11-08 | 2021-01-25 | Омрикс Биофармасьютикалс Лтд. | Гемостатическая композиция |
| CN116212008A (zh) * | 2023-03-15 | 2023-06-06 | 武汉康宁美生物科技有限公司 | 一种伤口创面消毒凝胶及其制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2532348A (en) * | 1946-12-12 | 1950-12-05 | Szent-Gyorgyi Albert | Blood clotting preparation |
| CH303082A (de) * | 1950-12-18 | 1954-11-15 | Hoechst Ag | Verfahren zur Herstellung eines haltbaren Thrombinpräparates von gesteigerter Wirksamkeit. |
-
1985
- 1985-08-06 US US06/763,056 patent/US4637815A/en not_active Expired - Fee Related
-
1986
- 1986-08-01 AT AT86305933T patent/ATE53299T1/de not_active IP Right Cessation
- 1986-08-01 DE DE8686305933T patent/DE3671700D1/de not_active Expired - Lifetime
- 1986-08-01 EP EP86305933A patent/EP0211629B1/de not_active Expired - Lifetime
- 1986-08-06 JP JP61184971A patent/JPS6259222A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DE3671700D1 (de) | 1990-07-12 |
| US4637815A (en) | 1987-01-20 |
| JPH0359045B2 (de) | 1991-09-09 |
| EP0211629A1 (de) | 1987-02-25 |
| JPS6259222A (ja) | 1987-03-14 |
| EP0211629B1 (de) | 1990-06-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |