ATE530640T1 - Integrin-bindungsdomäne der map-kinase - Google Patents

Integrin-bindungsdomäne der map-kinase

Info

Publication number
ATE530640T1
ATE530640T1 AT01271913T AT01271913T ATE530640T1 AT E530640 T1 ATE530640 T1 AT E530640T1 AT 01271913 T AT01271913 T AT 01271913T AT 01271913 T AT01271913 T AT 01271913T AT E530640 T1 ATE530640 T1 AT E530640T1
Authority
AT
Austria
Prior art keywords
map kinase
binding domain
integrin
integrin binding
methods
Prior art date
Application number
AT01271913T
Other languages
English (en)
Inventor
Michael Agrez
Nuzhat Ahmed
Original Assignee
Inter K Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inter K Pty Ltd filed Critical Inter K Pty Ltd
Application granted granted Critical
Publication of ATE530640T1 publication Critical patent/ATE530640T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/11Protein-serine/threonine kinases (2.7.11)
    • C12Y207/11024Mitogen-activated protein kinase (2.7.11.24), i.e. MAPK or MAPK2 or c-Jun N-terminal kinase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT01271913T 2000-12-22 2001-12-21 Integrin-bindungsdomäne der map-kinase ATE530640T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPR2305A AUPR230500A0 (en) 2000-12-22 2000-12-22 A method of modulating map kinase mediated cellular activity and agents useful in same
PCT/AU2001/001672 WO2002051993A1 (en) 2000-12-22 2001-12-21 MAP kinase integrin-binding domain

Publications (1)

Publication Number Publication Date
ATE530640T1 true ATE530640T1 (de) 2011-11-15

Family

ID=3826339

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01271913T ATE530640T1 (de) 2000-12-22 2001-12-21 Integrin-bindungsdomäne der map-kinase

Country Status (5)

Country Link
US (1) US7422883B2 (de)
EP (1) EP1352055B1 (de)
AT (1) ATE530640T1 (de)
AU (1) AUPR230500A0 (de)
WO (1) WO2002051993A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004281077B2 (en) * 2003-10-17 2010-12-02 Inter-K Pty Limited Methods and agents for the treatment of cancer
EP1805210A4 (de) 2004-09-09 2007-10-24 Auckland Uniservices Ltd Neue peptide und verfahren zur behandlungvon entzündungskrankheiten
US8080252B2 (en) * 2006-07-19 2011-12-20 The Cleveland Clinic Foundation Compounds and methods of modulating angiogenesis
ES2662036T3 (es) * 2007-02-28 2018-04-05 Yeda Research And Development Company Limited Secuencias que se dirigen al núcleo
DK2126064T3 (da) 2007-03-27 2012-09-10 Intrexon Corp MEK-ligander og polynukleotider til kodning af MEK-ligander
WO2009103127A1 (en) * 2008-02-22 2009-08-27 Inter-K Pty Limited Therapeutic peptides
JP2012518602A (ja) * 2009-02-23 2012-08-16 インター−ケイ ピーティーワイ リミテッド 複数の細胞活性化経路の阻害
EP2807180B1 (de) 2012-01-24 2018-03-28 InterK Peptide Therapeutics Limited Peptidmittel zur krebstherapie
WO2015040609A1 (en) 2013-09-17 2015-03-26 Yeda Research And Development Co. Ltd. Erk-derived peptides and uses thereof
WO2020107079A1 (en) * 2018-11-30 2020-06-04 Interk Peptide Therapeutics Limited Polypeptides and methods for improving skin conditions
US20200319174A1 (en) * 2019-04-17 2020-10-08 Jiangnan University Method for Detecting Human Soluble Asialoglycoprotein Receptor
CN116041482B (zh) * 2022-09-29 2024-05-03 江汉大学 一种结构肽段的cDNA、结构肽段和制备方法及应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE911869A1 (en) 1990-06-01 1991-12-04 Regeneron Pharma A family of map2 protein kinases
WO1992012236A1 (en) 1991-01-11 1992-07-23 The Regents Of The University Of California A NOVEL INTEGRIN β SUBUNIT AND USES THEREOF
US5962643A (en) 1991-07-11 1999-10-05 The Regents Of The University Of California Integrin β subunit and uses thereof
US6514745B1 (en) 1993-07-19 2003-02-04 The Regents Of The University Of California Oncoprotein protein kinase
US6495518B1 (en) 1994-06-13 2002-12-17 Vanderbilt University Method for importing biologically active molecules into cells
US5807746A (en) 1994-06-13 1998-09-15 Vanderbilt University Method for importing biologically active molecules into cells
WO1998016241A1 (en) 1996-10-15 1998-04-23 Vanderbilt University Method of disrupting cellular adhesion
US6007991A (en) 1997-03-28 1999-12-28 The Research Foundation Of Suny Antisense oligonucleotides for mitogen-activated protein kinases as therapy for cancer
PT1504764E (pt) 1997-08-08 2009-01-14 Univ California Tratamento da fibrose hepática com anticorpos contra integrina alfa-v-beta 6
US6133246A (en) 1997-08-13 2000-10-17 Isis Pharmaceuticals Inc. Antisense oligonucleotide compositions and methods for the modulation of JNK proteins
US5877309A (en) 1997-08-13 1999-03-02 Isis Pharmaceuticals, Inc. Antisense oligonucleotides against JNK
US6248558B1 (en) 1998-03-31 2001-06-19 Vanderbilt University Sequence and method for genetic engineering of proteins with cell membrane translocating activity
ATE385503T1 (de) 1999-06-28 2008-02-15 Inter K Pty Ltd Verfahren zur modulierung von integrin- vermittelter zellaktivitaet und hierfuer geeignete reagenzien
US6312956B1 (en) 1999-10-01 2001-11-06 Vanderbilt University Nuclear targeted peptide nucleic acid oligomer
WO2001097827A1 (en) 2000-06-16 2001-12-27 Argonex Pharmaceuticals Mhc peptides over-expressed on prostate cancer cells and methods of use

Also Published As

Publication number Publication date
AUPR230500A0 (en) 2001-01-25
US20050214755A1 (en) 2005-09-29
EP1352055A4 (de) 2004-07-07
US7422883B2 (en) 2008-09-09
EP1352055A1 (de) 2003-10-15
WO2002051993A1 (en) 2002-07-04
EP1352055B1 (de) 2011-10-26

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