ATE530638T1 - Pluripotente autologe stammzellen aus der mündlichen oder gastrointestinalen schleimhaut - Google Patents
Pluripotente autologe stammzellen aus der mündlichen oder gastrointestinalen schleimhautInfo
- Publication number
- ATE530638T1 ATE530638T1 AT08738220T AT08738220T ATE530638T1 AT E530638 T1 ATE530638 T1 AT E530638T1 AT 08738220 T AT08738220 T AT 08738220T AT 08738220 T AT08738220 T AT 08738220T AT E530638 T1 ATE530638 T1 AT E530638T1
- Authority
- AT
- Austria
- Prior art keywords
- stem cells
- oral
- pluripotent
- gastrointestinal mucosa
- autologous stem
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/38—Stomach; Intestine; Goblet cells; Oral mucosa; Saliva
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
- C12N5/0632—Cells of the oral mucosa
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US91424607P | 2007-04-26 | 2007-04-26 | |
US91553807P | 2007-05-02 | 2007-05-02 | |
PCT/IL2008/000518 WO2008132722A1 (en) | 2007-04-26 | 2008-04-16 | Pluripotent autologous stem cells from oral mucosa and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE530638T1 true ATE530638T1 (de) | 2011-11-15 |
Family
ID=39709271
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT08738220T ATE530638T1 (de) | 2007-04-26 | 2008-04-16 | Pluripotente autologe stammzellen aus der mündlichen oder gastrointestinalen schleimhaut |
Country Status (5)
Country | Link |
---|---|
US (2) | US9534201B2 (de) |
EP (1) | EP2137300B1 (de) |
CN (1) | CN101668848B (de) |
AT (1) | ATE530638T1 (de) |
WO (1) | WO2008132722A1 (de) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009150415A2 (en) * | 2008-06-13 | 2009-12-17 | University College Cardiff Consultants Limited | Novel adult progenitor cell |
WO2010090843A2 (en) * | 2009-01-20 | 2010-08-12 | University Of Southern California | Gingiva derived stem cell and its application in immunomodulation and reconstruction |
WO2012009581A2 (en) | 2010-07-14 | 2012-01-19 | University Of Southern California | Pharmaceutical compositions comprising gingiva-derived mesenchymal stem cells and methods of treating inflammation, wound healing and contact hypersensitivity |
EP2782587B1 (de) * | 2011-11-21 | 2018-11-07 | Ramot at Tel Aviv University, Ltd. | Aus stammzellen gewonnene nervenzellen zur zelltherapie bei neurologischen krankheiten |
US10357517B1 (en) * | 2012-10-01 | 2019-07-23 | University Of South Florida | Methods of treating epilepsy using neural stem cells that express nanog, SSEA-4, OCT-4, MIR-34B, MIR-34C and MIR-592 |
RU2510833C1 (ru) * | 2012-11-08 | 2014-04-10 | Федеральное государственное бюджетное учреждение науки Институт Биологии Развития им. Н.К. Кольцова Российской Академии Наук | Клеточный продукт для лечения и коррекции печеночной недостаточности |
KR20150140967A (ko) * | 2014-06-09 | 2015-12-17 | 가천대학교 산학협력단 | 신경인성 방광증 치료용 약학 조성물 |
EP3426770A1 (de) | 2016-03-09 | 2019-01-16 | Avita International Ltd. | Mesenchymale und neuronale marker exprimierende stammzellen, zusammensetzungen daraus und verfahren zur herstellung davon |
GB201615714D0 (en) * | 2016-09-15 | 2016-11-02 | Univ Of Sheffield The | Otic progenitor identification and isolation |
CA3112650A1 (en) * | 2018-03-29 | 2019-10-03 | The University Of North Carolina At Chapel Hill | Stem/progenitor cells from duodenal brunner's glands and methods of isolating and using them |
DE112020001342T5 (de) | 2019-03-19 | 2022-01-13 | President and Fellows of Harvard College | Verfahren und Zusammensetzungen zum Editing von Nukleotidsequenzen |
CN112094804A (zh) * | 2019-06-18 | 2020-12-18 | 中国医学科学院基础医学研究所 | 一种异质性干细胞群、其制备方法及用途 |
JP2023525304A (ja) | 2020-05-08 | 2023-06-15 | ザ ブロード インスティテュート,インコーポレーテッド | 標的二本鎖ヌクレオチド配列の両鎖同時編集のための方法および組成物 |
WO2022067130A2 (en) | 2020-09-24 | 2022-03-31 | The Broad Institute, Inc. | Prime editing guide rnas, compositions thereof, and methods of using the same |
WO2022150790A2 (en) | 2021-01-11 | 2022-07-14 | The Broad Institute, Inc. | Prime editor variants, constructs, and methods for enhancing prime editing efficiency and precision |
AU2022325166A1 (en) | 2021-08-06 | 2024-02-08 | President And Fellows Of Harvard College | Improved prime editors and methods of use |
CN113730329A (zh) * | 2021-08-25 | 2021-12-03 | 杭州美约健康管理有限公司 | 自体粘膜细胞再生修复组合物、制备方法及其应用 |
CN113789298A (zh) * | 2021-09-23 | 2021-12-14 | 北京大学第三医院(北京大学第三临床医学院) | 一种促进口腔黏膜间充质干细胞再生能力的方法及其应用 |
WO2023076898A1 (en) | 2021-10-25 | 2023-05-04 | The Broad Institute, Inc. | Methods and compositions for editing a genome with prime editing and a recombinase |
WO2023102538A1 (en) | 2021-12-03 | 2023-06-08 | The Broad Institute, Inc. | Self-assembling virus-like particles for delivery of prime editors and methods of making and using same |
WO2023205687A1 (en) | 2022-04-20 | 2023-10-26 | The Broad Institute, Inc. | Improved prime editing methods and compositions |
WO2023240137A1 (en) | 2022-06-08 | 2023-12-14 | The Board Institute, Inc. | Evolved cas14a1 variants, compositions, and methods of making and using same in genome editing |
WO2024077267A1 (en) | 2022-10-07 | 2024-04-11 | The Broad Institute, Inc. | Prime editing methods and compositions for treating triplet repeat disorders |
CN115466725A (zh) * | 2022-10-24 | 2022-12-13 | 北京大学口腔医学院 | 间充质干细胞的制备方法 |
Family Cites Families (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3753357A (en) | 1970-12-14 | 1973-08-21 | Ovitron Res Corp | Method and apparatus for the preservation of cells and tissues |
US4199022A (en) | 1978-12-08 | 1980-04-22 | The United States Of America As Represented By The Department Of Energy | Method of freezing living cells and tissues with improved subsequent survival |
US4559298A (en) | 1982-11-23 | 1985-12-17 | American National Red Cross | Cryopreservation of biological materials in a non-frozen or vitreous state |
WO1992003917A1 (en) | 1990-08-29 | 1992-03-19 | Genpharm International | Homologous recombination in mammalian cells |
AU2515992A (en) | 1991-08-20 | 1993-03-16 | Genpharm International, Inc. | Gene targeting in animal cells using isogenic dna constructs |
US5919449A (en) * | 1995-05-30 | 1999-07-06 | Diacrin, Inc. | Porcine cardiomyocytes and their use in treatment of insufficient cardiac function |
US6485722B1 (en) | 1996-03-01 | 2002-11-26 | Regents Of The University Of Minnesota | Method for selective engraftment of drug-resistant hematopoietic stem cells |
US5873254A (en) | 1996-09-06 | 1999-02-23 | Interface Multigrad Technology | Device and methods for multigradient directional cooling and warming of biological samples |
US5830698A (en) | 1997-03-14 | 1998-11-03 | Idec Pharmaceuticals Corporation | Method for integrating genes at specific sites in mammalian cells via homologous recombination and vectors for accomplishing the same |
US6310195B1 (en) | 1997-06-24 | 2001-10-30 | Imclone Systems Incorporated | Nucleic acid encoding a lectin-derived progenitor cell preservation factor |
EP1007631B2 (de) | 1997-07-14 | 2009-02-18 | Osiris Therapeutics, Inc. | Herzmuskelregenerierung unter verwendung mesenchymaler stammzellen |
US5968829A (en) * | 1997-09-05 | 1999-10-19 | Cytotherapeutics, Inc. | Human CNS neural stem cells |
US6482937B1 (en) | 1997-10-09 | 2002-11-19 | Biotransplant, Inc. | Porcine Oct-4 promoter |
CA2242680A1 (en) * | 1998-07-09 | 2000-01-09 | Universite De Sherbrooke | Pure, viable and human epithelial cell preparations obtained from digestive tissue and method of preparation thereof |
WO2000006701A1 (en) * | 1998-07-31 | 2000-02-10 | Genzyme Corporation | Improvement of cardiac function by mesenchymal stem cell transplantation |
GB9819912D0 (en) | 1998-09-11 | 1998-11-04 | Univ Edinburgh | Propagation and/or derivation of embryonic stem cells |
US6663870B2 (en) * | 1998-12-07 | 2003-12-16 | Zymogenetics, Inc. | Methods for promoting growth of bone using zvegf3 |
US6087168A (en) * | 1999-01-20 | 2000-07-11 | Cedars Sinai Medical Center | Conversion of non-neuronal cells into neurons: transdifferentiation of epidermal cells |
US7015037B1 (en) * | 1999-08-05 | 2006-03-21 | Regents Of The University Of Minnesota | Multiponent adult stem cells and methods for isolation |
ES2300320T3 (es) * | 2000-02-26 | 2008-06-16 | Artecel, Inc. | Celulas madre pluripotentes generadas a partir de celulas del estroma derivadas de tejido adiposo y sus usos. |
AU7707801A (en) * | 2000-07-21 | 2002-02-05 | Us Health | Adult human dental pulp stem cells in vitro and in vivo |
EP1303588B1 (de) * | 2000-07-26 | 2012-10-24 | Boston Scientific Limited | Therapeutische angiogenese durch die transplantation von aus knochenmark gewonnen zellen in ischämischen myokard- und muskelgeweben |
CN1533431A (zh) * | 2001-04-13 | 2004-09-29 | 细胞移植的方法和试剂 | |
US20020197240A1 (en) * | 2001-05-15 | 2002-12-26 | Chiu Ray C. | Marrow stem cell (MSC) transplantation for use in tissue and/or organ repair |
JP2005502356A (ja) * | 2001-09-12 | 2005-01-27 | デヴェロゲン アクチエンゲゼルシャフト フュア エントヴィックルングスビオローギッシェ フォルシュング | 治療のための腸内幹細胞の分離、培養および分化方法 |
US6767740B2 (en) * | 2001-10-09 | 2004-07-27 | Roger Anton Sramek | Stem cell and dental pulp harvesting method and apparatus |
AUPS187202A0 (en) * | 2002-04-22 | 2002-05-30 | Griffith University | Method for culturing stem cells |
CA2493768A1 (en) | 2002-07-23 | 2004-01-29 | Nanodiagnostics, Inc. | Embryonic stem cell markers and uses thereof |
KR100484550B1 (ko) | 2003-01-23 | 2005-04-22 | (주)안트로젠 | 세포 이식을 위한 세포의 생산 방법 |
RU2345133C2 (ru) * | 2003-03-12 | 2009-01-27 | Релайанс Лайф Сайенсиз Пвт. Лтд. | Получение терминально дифференцированных дофаминергических нейронов из эмбриональных стволовых клеток человека |
US20040247574A1 (en) * | 2003-05-27 | 2004-12-09 | Christopherson Kent W. | Methods for enhancing stem cell engraftment during transplantation |
US8518390B2 (en) | 2003-06-27 | 2013-08-27 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells |
US8491883B2 (en) | 2003-06-27 | 2013-07-23 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of amyotrophic lateral sclerosis using umbilical derived cells |
AU2004252567B2 (en) | 2003-06-27 | 2011-10-06 | Ethicon, Incorporated | Repair and regeneration of ocular tissue using postpartum-derived cells |
CN1597935A (zh) * | 2003-09-15 | 2005-03-23 | 林东贺 | 活细胞胎盘素脐带干细胞的提取方法 |
CN1611598A (zh) * | 2004-05-17 | 2005-05-04 | 西北农林科技大学 | 人胎儿胰腺干细胞系及其建立方法 |
ES2245879B1 (es) | 2004-05-21 | 2006-12-16 | Universidad De Malaga | Composicion para la reparacion osea o cartilaginosa. |
WO2006017567A2 (en) | 2004-08-02 | 2006-02-16 | The Johns Hopkins University | Customizing stem cell-derived cardiomyocytes for transplantation |
CA2593549C (en) * | 2005-01-07 | 2016-04-26 | Wake Forest University Health Sciences | Regeneration of pancreatic islets by amniotic fluid stem cell therapy |
WO2007020611A2 (en) | 2005-08-19 | 2007-02-22 | ECBIO - Investigação e Desenvolvimento em Biotecnologia, S.A. | Adult human neural stem/progenitor cells from the olfactory epithelium and olfactory lamina propria, isolation method, proliferation and differentiation in serum free culture medium and utilization for transplantation |
KR101505202B1 (ko) | 2006-03-07 | 2015-03-27 | 지타 쉬로프 | 인간 배아 줄기 세포 및 그의 유도체를 포함하는 조성물, 그의 사용 방법 및 제조 방법 |
WO2010056988A2 (en) | 2008-11-13 | 2010-05-20 | University Of South Florida | Methods of treating stroke using stem cell-like menstrual blood cells |
US9468656B2 (en) | 2012-04-20 | 2016-10-18 | Medela Holding Ag | Stem cell preparations and methods of use |
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2008
- 2008-04-16 CN CN200880013622.0A patent/CN101668848B/zh active Active
- 2008-04-16 AT AT08738220T patent/ATE530638T1/de not_active IP Right Cessation
- 2008-04-16 EP EP08738220A patent/EP2137300B1/de active Active
- 2008-04-16 WO PCT/IL2008/000518 patent/WO2008132722A1/en active Application Filing
-
2009
- 2009-10-26 US US12/605,781 patent/US9534201B2/en active Active
-
2016
- 2016-11-23 US US15/360,555 patent/US10570369B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US10570369B2 (en) | 2020-02-25 |
CN101668848B (zh) | 2014-10-22 |
EP2137300A1 (de) | 2009-12-30 |
US20170137778A1 (en) | 2017-05-18 |
WO2008132722A1 (en) | 2008-11-06 |
CN101668848A (zh) | 2010-03-10 |
US9534201B2 (en) | 2017-01-03 |
EP2137300B1 (de) | 2011-10-26 |
US20100080780A1 (en) | 2010-04-01 |
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Legal Events
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