ATE525653T1 - Bildung von doppelschichten amphipathischer moleküle - Google Patents
Bildung von doppelschichten amphipathischer moleküleInfo
- Publication number
- ATE525653T1 ATE525653T1 AT07789069T AT07789069T ATE525653T1 AT E525653 T1 ATE525653 T1 AT E525653T1 AT 07789069 T AT07789069 T AT 07789069T AT 07789069 T AT07789069 T AT 07789069T AT E525653 T1 ATE525653 T1 AT E525653T1
- Authority
- AT
- Austria
- Prior art keywords
- droplets
- amphipathic molecules
- bilayers
- formation
- lipid
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- 150000002632 lipids Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 238000010276 construction Methods 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
- B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
- B01L3/502792—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics for moving individual droplets on a plate, e.g. by locally altering surface tension
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/5432—Liposomes or microcapsules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/16—Surface properties and coatings
- B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
- B01L2400/0427—Electrowetting
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/305—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Micrococcaceae (F)
- G01N2333/31—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/12—Condition responsive control
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Dispersion Chemistry (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Fluid Mechanics (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Medicinal Preparation (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0614835.7A GB0614835D0 (en) | 2006-07-26 | 2006-07-26 | Formation of bilayers of amphipathic molecules |
| PCT/GB2007/002856 WO2008012552A1 (en) | 2006-07-26 | 2007-07-26 | Formation of bilayers of amphipathic molecules |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE525653T1 true ATE525653T1 (de) | 2011-10-15 |
Family
ID=37006184
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07789069T ATE525653T1 (de) | 2006-07-26 | 2007-07-26 | Bildung von doppelschichten amphipathischer moleküle |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8268627B2 (enExample) |
| EP (1) | EP2047266B1 (enExample) |
| JP (1) | JP5235879B2 (enExample) |
| AT (1) | ATE525653T1 (enExample) |
| GB (1) | GB0614835D0 (enExample) |
| WO (1) | WO2008012552A1 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2424792C2 (ru) | 2004-05-03 | 2011-07-27 | Хермес Байесайенсиз, Инк. | Липосомы, используемые для доставки лекарственных средств |
| NZ579083A (en) | 2007-02-20 | 2012-07-27 | Oxford Nanopore Tech Ltd | Lipid bilayer sensor system |
| GB0716264D0 (en) * | 2007-08-21 | 2007-09-26 | Isis Innovation | Bilayers |
| GB0724736D0 (en) | 2007-12-19 | 2008-01-30 | Oxford Nanolabs Ltd | Formation of layers of amphiphilic molecules |
| EP2293921A4 (en) * | 2008-05-22 | 2013-05-22 | Univ California | MEMBRANE PROBLEMS AND MEMBRANES MADE FROM THESE |
| DE102009053490A1 (de) * | 2009-11-16 | 2011-05-26 | Schaeffler Technologies Gmbh & Co. Kg | Turbolader einer Brennkraftmaschine mit einem elektrischen Energiefluss |
| GB201119032D0 (en) * | 2011-11-03 | 2011-12-14 | Isis Innovation | Multisomes: encapsulated droplet networks |
| GB201202519D0 (en) | 2012-02-13 | 2012-03-28 | Oxford Nanopore Tech Ltd | Apparatus for supporting an array of layers of amphiphilic molecules and method of forming an array of layers of amphiphilic molecules |
| GB201219201D0 (en) | 2012-10-25 | 2012-12-12 | Isis Innovation | Hydrogel network |
| GB201219196D0 (en) | 2012-10-25 | 2012-12-12 | Isis Innovation | Droplet assembly method |
| US9823235B2 (en) * | 2012-10-26 | 2017-11-21 | Oxford Nanopre Technologies Ltd. | Droplet interfaces |
| GB201313121D0 (en) | 2013-07-23 | 2013-09-04 | Oxford Nanopore Tech Ltd | Array of volumes of polar medium |
| JP6078848B2 (ja) * | 2012-11-20 | 2017-02-15 | 公益財団法人神奈川科学技術アカデミー | 脂質二重膜の形成方法及びそのための器具 |
| KR102284661B1 (ko) * | 2012-12-07 | 2021-08-02 | 옥스포드 유니버시티 이노베이션 리미티드 | 3d 프린팅에 의한 비말 어셈블리 |
| GB201418512D0 (en) | 2014-10-17 | 2014-12-03 | Oxford Nanopore Tech Ltd | Electrical device with detachable components |
| WO2016081723A1 (en) * | 2014-11-21 | 2016-05-26 | Icahn School Of Medicine At Mount Sinai | Method of forming a lipid bilayer |
| WO2017004504A1 (en) | 2015-07-02 | 2017-01-05 | The University Of Massachusetts | Membrane and droplet-interface bilayer systems and methods |
| US10481120B1 (en) | 2015-08-06 | 2019-11-19 | University Of Tennessee Research Foundation | Droplet based measurement of specific capacitance and interfacial tensions |
| BR112018006922B1 (pt) | 2015-10-16 | 2023-11-21 | Ipsen Biopharm Ltd | Composições de irinotecano lipossômico estabilizado para armazenamento |
| US10690680B2 (en) | 2015-11-17 | 2020-06-23 | Paris Sciences Et Lettres - Quartier Latin | Method for analyzing the activity of an ion channel |
| GB201611770D0 (en) | 2016-07-06 | 2016-08-17 | Oxford Nanopore Tech | Microfluidic device |
| GB201619930D0 (en) | 2016-11-24 | 2017-01-11 | Oxford Nanopore Tech | Apparatus and methods for controlling insertion of a membrane channel into a membrane |
| JP6877028B2 (ja) * | 2017-03-28 | 2021-05-26 | 国立大学法人福井大学 | 脂質二重膜形成装置、脂質二重膜形成方法、および評価システム |
| GB2568895B (en) | 2017-11-29 | 2021-10-27 | Oxford Nanopore Tech Ltd | Microfluidic device |
| GB2569630B (en) * | 2017-12-21 | 2022-10-12 | Sharp Life Science Eu Ltd | Droplet Interfaces in Electro-wetting Devices |
| CN112203767B (zh) | 2018-05-24 | 2023-04-11 | 牛津纳米孔科技公司 | 电润湿装置中的液滴界面 |
| KR20210138594A (ko) | 2019-03-12 | 2021-11-19 | 옥스포드 나노포어 테크놀로지즈 피엘씨 | 나노포어 감지 디바이스 및 이를 작동하는 방법 및 형성하는 방법 |
| EP3756761B1 (en) * | 2019-06-25 | 2025-08-06 | Sharp Life Science (EU) Limited | Microfluidic device and a method of manipulating droplets therein |
| EP3756762B1 (en) * | 2019-06-25 | 2025-08-06 | Sharp Life Science (EU) Limited | Method of manipulating droplets in a microfluidic device |
| WO2022013551A1 (en) | 2020-07-17 | 2022-01-20 | Oxford Nanopore Technologies Limited | Nanopore sensing device |
| CN116297721A (zh) * | 2021-12-21 | 2023-06-23 | 成都齐碳科技有限公司 | 成膜方法、包含膜的系统及应用 |
| GB202202716D0 (en) | 2022-02-28 | 2022-04-13 | Oxford Nanopore Tech Plc | Apparatus and methods for controlling insertion of a membrane channel into a membrane |
| CN114908358B8 (zh) * | 2022-04-14 | 2024-06-21 | 孔确(成都)科技有限公司 | 一种两亲性分子层的制备方法及装置 |
| GB202313035D0 (en) * | 2023-08-25 | 2023-10-11 | Univ Oxford Innovation Ltd | Power unit |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03118832A (ja) * | 1989-09-29 | 1991-05-21 | Toshiba Corp | 二分子膜の形成方法 |
| JP3118832B2 (ja) | 1990-11-20 | 2000-12-18 | 松下電器産業株式会社 | アルカリ蓄電池 |
| US6962747B1 (en) | 2001-10-23 | 2005-11-08 | Sandia Corporation | Self-assembled lipid bilayer materials |
| US8039247B2 (en) | 2004-01-21 | 2011-10-18 | Japan Science And Technology Agency | Method of forming planar lipid double membrane for membrane protein analysis and apparatus therefor |
| JP4953044B2 (ja) | 2005-05-09 | 2012-06-13 | 財団法人生産技術研究奨励会 | 脂質二重膜の形成方法およびその装置 |
| JP5114702B2 (ja) | 2005-07-29 | 2013-01-09 | 国立大学法人 東京大学 | 両親媒性単分子膜の接触による二分子膜の形成方法およびその装置 |
| US7776927B2 (en) | 2007-03-28 | 2010-08-17 | President And Fellows Of Harvard College | Emulsions and techniques for formation |
-
2006
- 2006-07-26 GB GBGB0614835.7A patent/GB0614835D0/en not_active Ceased
-
2007
- 2007-07-26 US US12/375,103 patent/US8268627B2/en active Active
- 2007-07-26 JP JP2009521345A patent/JP5235879B2/ja active Active
- 2007-07-26 AT AT07789069T patent/ATE525653T1/de not_active IP Right Cessation
- 2007-07-26 WO PCT/GB2007/002856 patent/WO2008012552A1/en not_active Ceased
- 2007-07-26 EP EP07789069A patent/EP2047266B1/en active Active
-
2012
- 2012-09-07 US US13/607,337 patent/US8691586B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US8268627B2 (en) | 2012-09-18 |
| GB0614835D0 (en) | 2006-09-06 |
| JP2010503517A (ja) | 2010-02-04 |
| US20100032627A1 (en) | 2010-02-11 |
| US8691586B2 (en) | 2014-04-08 |
| JP5235879B2 (ja) | 2013-07-10 |
| WO2008012552A1 (en) | 2008-01-31 |
| US20130146815A1 (en) | 2013-06-13 |
| EP2047266B1 (en) | 2011-09-21 |
| EP2047266A1 (en) | 2009-04-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |