ATE524563T1 - System zur herstellung synthetischer promotoren - Google Patents
System zur herstellung synthetischer promotorenInfo
- Publication number
- ATE524563T1 ATE524563T1 AT06749942T AT06749942T ATE524563T1 AT E524563 T1 ATE524563 T1 AT E524563T1 AT 06749942 T AT06749942 T AT 06749942T AT 06749942 T AT06749942 T AT 06749942T AT E524563 T1 ATE524563 T1 AT E524563T1
- Authority
- AT
- Austria
- Prior art keywords
- combined
- transcription
- vector
- reporter gene
- regulatory elements
- Prior art date
Links
- 238000013518 transcription Methods 0.000 abstract 4
- 230000035897 transcription Effects 0.000 abstract 4
- 108700008625 Reporter Genes Proteins 0.000 abstract 2
- 230000001105 regulatory effect Effects 0.000 abstract 2
- 108020004414 DNA Proteins 0.000 abstract 1
- 102000053602 DNA Human genes 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 238000011144 upstream manufacturing Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1086—Preparation or screening of expression libraries, e.g. reporter assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1051—Gene trapping, e.g. exon-, intron-, IRES-, signal sequence-trap cloning, trap vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/907,620 US7063947B2 (en) | 2004-04-08 | 2005-04-08 | System for producing synthetic promoters |
| PCT/US2006/013740 WO2006110852A1 (en) | 2005-04-08 | 2006-04-10 | System for producing synthetic promoters |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE524563T1 true ATE524563T1 (de) | 2011-09-15 |
Family
ID=37087363
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06749942T ATE524563T1 (de) | 2005-04-08 | 2006-04-10 | System zur herstellung synthetischer promotoren |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US7063947B2 (de) |
| EP (1) | EP1877575B1 (de) |
| JP (1) | JP4913126B2 (de) |
| KR (1) | KR101086102B1 (de) |
| CN (1) | CN101189348B (de) |
| AT (1) | ATE524563T1 (de) |
| WO (1) | WO2006110852A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7709625B2 (en) * | 2004-06-10 | 2010-05-04 | The Board Of Regents Of The University Of Texas | Methods and compositions for bone marrow stem cell-derived macrophage delivery of genes for gene therapy |
| WO2008107725A1 (en) * | 2007-03-05 | 2008-09-12 | Regulon S.A. | A method for the construction of cancer-specific promoters using functional genomics |
| EP2479278A1 (de) * | 2011-01-25 | 2012-07-25 | Synpromics Ltd. | Verfahren zur Konstruktion spezifischer Promotoren |
| US11377663B1 (en) | 2011-08-30 | 2022-07-05 | Monsanto Technology Llc | Genetic regulatory elements |
| US12188028B1 (en) | 2011-08-30 | 2025-01-07 | Monsanto Technology, Llc | Methods for making genetic regulatory elements |
| WO2013163346A1 (en) | 2012-04-25 | 2013-10-31 | The Regents Of The University Of California | Synthetic promoter for modulating gene expression |
| EP3064578B1 (de) * | 2014-02-26 | 2021-01-13 | Terumo Kabushiki Kaisha | Verfahren zur herstellung einer zellpopulation mit hoher zielzellenreinheit |
| WO2016057954A2 (en) | 2014-10-10 | 2016-04-14 | Board Of Regents Of The University Of Texas System | Exogenous terminators for controlling fungal gene expression |
| WO2016089516A2 (en) * | 2014-10-31 | 2016-06-09 | Board Of Regents, The University Of Texas System | Short exogenous promoter for high level expression in fungi |
| EP3433366B1 (de) * | 2016-03-25 | 2022-05-18 | GenomeFrontier Therapeutics, Inc. | Kit zur herstellung eines transposons und verwendung davon |
| GB201705121D0 (en) * | 2017-03-30 | 2017-05-17 | Norwegian Univ Of Science And Tech | Modulation of gene expression |
| US10745693B2 (en) * | 2017-04-04 | 2020-08-18 | Wisconsin Alumni Research Foundation | Methods of designing programmable inducible promoters |
| CN110741086B (zh) * | 2017-04-19 | 2024-04-09 | 免疫医疗有限公司 | 具有用户定义的功能的哺乳动物启动子的计算机设计 |
| EP3502692A1 (de) * | 2017-12-20 | 2019-06-26 | Aposcience AG | Wirksamkeitstest für sekretom |
| CN108866057B (zh) * | 2018-07-06 | 2020-08-04 | 江南大学 | 一种大肠杆菌压力响应型启动子及其制备方法 |
| WO2021146508A2 (en) * | 2020-01-17 | 2021-07-22 | Asklepios Biopharmaceutical, Inc. | Systems and methods for synthetic regulatory sequence design or production |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6087164A (en) * | 1997-10-03 | 2000-07-11 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Methods and compositions for inducing tumor-specific cytotoxicity |
| US6294358B1 (en) * | 1999-09-07 | 2001-09-25 | Thermogen, Inc. | Thermus promoters for gene expression |
| WO2002010368A1 (en) * | 2000-07-21 | 2002-02-07 | Chiba Prefecture | Tumor-specific promoters |
| AU2001292718A1 (en) * | 2000-09-12 | 2002-03-26 | Transgenetics Incorporated | Microarrayed organization of transcription factor target genes |
| WO2002063032A1 (en) * | 2001-02-05 | 2002-08-15 | Shen Quan Pan | Methods and kits for identifying scavengers of reactive oxygen species (ros) |
| AU2002305585A1 (en) * | 2001-04-23 | 2002-11-05 | Michael F. Chou | Transcription factor network discovery methods |
| US20030211478A1 (en) * | 2002-05-08 | 2003-11-13 | Gentel Corporation | Transcription factor profiling on a solid surface |
| CA2504593C (en) * | 2002-11-04 | 2016-08-09 | Advisys, Inc. | Synthetic muscle promoters with activities exceeding naturally occurring regulatory sequences in cardiac cells |
| US20040115794A1 (en) * | 2002-12-12 | 2004-06-17 | Affymetrix, Inc. | Methods for detecting transcriptional factor binding sites |
-
2005
- 2005-04-08 US US10/907,620 patent/US7063947B2/en not_active Expired - Lifetime
- 2005-10-31 US US11/163,794 patent/US20060057610A1/en not_active Abandoned
-
2006
- 2006-04-10 WO PCT/US2006/013740 patent/WO2006110852A1/en not_active Ceased
- 2006-04-10 JP JP2008505665A patent/JP4913126B2/ja not_active Expired - Fee Related
- 2006-04-10 KR KR1020077026031A patent/KR101086102B1/ko active Active
- 2006-04-10 CN CN200680018777.4A patent/CN101189348B/zh not_active Expired - Fee Related
- 2006-04-10 EP EP06749942A patent/EP1877575B1/de not_active Not-in-force
- 2006-04-10 AT AT06749942T patent/ATE524563T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN101189348A (zh) | 2008-05-28 |
| US20060057610A1 (en) | 2006-03-16 |
| CN101189348B (zh) | 2014-07-09 |
| EP1877575B1 (de) | 2011-09-14 |
| JP4913126B2 (ja) | 2012-04-11 |
| WO2006110852A1 (en) | 2006-10-19 |
| KR20080024110A (ko) | 2008-03-17 |
| KR101086102B1 (ko) | 2011-11-25 |
| EP1877575A1 (de) | 2008-01-16 |
| US7063947B2 (en) | 2006-06-20 |
| JP2009529855A (ja) | 2009-08-27 |
| US20050227246A1 (en) | 2005-10-13 |
| EP1877575A4 (de) | 2008-06-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE524563T1 (de) | System zur herstellung synthetischer promotoren | |
| Leger et al. | RNA modifications detection by comparative Nanopore direct RNA sequencing | |
| Woo et al. | Programming of plant leaf senescence with temporal and inter-organellar coordination of transcriptome in Arabidopsis | |
| Karlik et al. | LncRNAs: genetic and epigenetic effects in plants | |
| Li et al. | Directional RNA-seq reveals highly complex condition-dependent transcriptomes in E. coli K12 through accurate full-length transcripts assembling | |
| WO2010062913A3 (en) | Methods and systems for analysis of sequencing data | |
| AU2020331968A8 (en) | Compositions and methods for identifying regulators of cell type fate specification | |
| WO2006060653A3 (en) | Lung cancer prognostics | |
| Stotz et al. | Tracking the shift to ‘postgenomics’ | |
| Wu et al. | NF90/ILF3 is a transcription factor that promotes proliferation over differentiation by hierarchical regulation in K562 erythroleukemia cells | |
| CA2812115C (en) | Epigenetic markers of colorectal cancers and diagnostic methods using the same | |
| D'Agostino et al. | Advances in genomics, transcriptomics and proteomics of toxin‐producing cyanobacteria | |
| Wang et al. | Genetic variability, local selection and demographic history: genomic evidence of evolving towards allopatric speciation in Asian seabass | |
| WO2021127436A3 (en) | High-throughput single-cell libraries and methods of making and of using | |
| WO2017201102A8 (en) | Method of improved sequencing by strand identification | |
| WO2021262671A3 (en) | Parallel analysis of individual cells for rna expression and dna from targeted tagmentation by sequencing | |
| PH12019500791A1 (en) | Efficient data structures for bioinformatics information presentation | |
| NZ601353A (en) | Cell lines and methods for making and using them | |
| DK1576094T3 (da) | Fremgangsmåder til at danne modificerede promotere resulterende i varierende genekspressionsniveauer | |
| Mohanty et al. | Role of lncRNAs in health and disease—size and shape matter | |
| WO2005083429A8 (en) | Breast cancer prognostics | |
| Pandey et al. | Genetics of gene expression in CNS | |
| Gao et al. | Structural and functional analyses of hub microRNAs in an integrated gene regulatory network of Arabidopsis | |
| ATE490319T1 (de) | Auswahl und anreicherung von proteinen durch in- vitro-untergliederung | |
| Arnold et al. | Emerging insights into enhancer biology and function |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |