ATE524542T1 - Aus knochenmarksstützzellen stammende schwann'sche zellen - Google Patents
Aus knochenmarksstützzellen stammende schwann'sche zellenInfo
- Publication number
- ATE524542T1 ATE524542T1 AT02738782T AT02738782T ATE524542T1 AT E524542 T1 ATE524542 T1 AT E524542T1 AT 02738782 T AT02738782 T AT 02738782T AT 02738782 T AT02738782 T AT 02738782T AT E524542 T1 ATE524542 T1 AT E524542T1
- Authority
- AT
- Austria
- Prior art keywords
- cells
- differentiation
- schwann
- myeloid
- medium
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/383—Nerve cells, e.g. dendritic cells, Schwann cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3878—Nerve tissue, brain, spinal cord, nerves, dura mater
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0622—Glial cells, e.g. astrocytes, oligodendrocytes; Schwann cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/01—Modulators of cAMP or cGMP, e.g. non-hydrolysable analogs, phosphodiesterase inhibitors, cholera toxin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
- C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
- C12N2506/1353—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from bone marrow mesenchymal stem cells (BM-MSC)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001190251A JP3886346B2 (ja) | 2001-06-22 | 2001-06-22 | 骨髄間質細胞由来Schwann細胞を含む神経再生用医薬組成物 |
PCT/JP2002/006249 WO2003000871A1 (fr) | 2001-06-22 | 2002-06-21 | Cellules de schwann provenant de cellules myeloides interstitielles |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE524542T1 true ATE524542T1 (de) | 2011-09-15 |
Family
ID=19029054
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02738782T ATE524542T1 (de) | 2001-06-22 | 2002-06-21 | Aus knochenmarksstützzellen stammende schwann'sche zellen |
Country Status (8)
Country | Link |
---|---|
US (2) | US6989271B2 (de) |
EP (2) | EP2345715A3 (de) |
JP (1) | JP3886346B2 (de) |
AT (1) | ATE524542T1 (de) |
CA (1) | CA2450789C (de) |
DK (1) | DK1405906T3 (de) |
ES (1) | ES2369259T3 (de) |
WO (1) | WO2003000871A1 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050265983A1 (en) * | 2002-11-17 | 2005-12-01 | Eldad Melamed | Methods, nucleic acid constructs and cells for treating neurodegenerative disorders |
ES2524996T3 (es) | 2005-06-16 | 2014-12-16 | Ramot At Tel Aviv University Ltd. | Células aisladas y poblaciones que comprenden a las mismas para el tratamiento de enfermedades del SNC |
JP5662147B2 (ja) * | 2007-08-15 | 2015-01-28 | サンバイオ,インコーポレイティド | 神経変性を治療するための方法及び組成物 |
US8283160B2 (en) | 2007-09-11 | 2012-10-09 | Frey Ii William H | Methods, pharmaceutical compositions and articles of manufacture for administering therapeutic cells to the animal central nervous system |
KR100973324B1 (ko) | 2007-11-23 | 2010-07-30 | 재단법인서울대학교산학협력재단 | 사람 중간엽 줄기세포에서 운동 신경세포로의 분화 유도방법 |
PL2222839T3 (pl) | 2007-12-03 | 2016-02-29 | Sanbio Inc | Sposoby i kompozycje do modulowania i różnicowania pluripotencjalnych komórek |
ES2594229T3 (es) | 2008-04-30 | 2016-12-16 | Sanbio, Inc. | Células de regeneración nerviosa con alteraciones en la metilación del ADN |
DK2620493T3 (da) | 2008-05-28 | 2019-07-01 | Univ Ramot | Mesenkymale stamceller til behandling af CNS-sygdomme |
US20120263681A1 (en) * | 2011-04-12 | 2012-10-18 | Fujifilm Corporation | Composition comprising cell and biocompatible polymer |
EP2806881A1 (de) | 2012-01-27 | 2014-12-03 | SanBio, Inc. | Verfahren und zusammensetzungen zur modulation der angiogenese und vaskulogenese |
CN104519891B (zh) | 2012-05-16 | 2019-03-22 | 桑比欧公司 | 用于治疗创伤性脑损伤和用于调节神经原性细胞迁移的方法和组合物 |
US9326999B2 (en) | 2012-10-09 | 2016-05-03 | Sanbio, Inc. | Methods and compositions for treatment of retinal degeneration |
US10675382B2 (en) * | 2014-09-12 | 2020-06-09 | Kyoto Prefectural Public University Corporation | Schwann cells and method for preparing same |
WO2017147491A1 (en) * | 2016-02-25 | 2017-08-31 | University Of Miami | Production of schwann cells |
CA3047329A1 (en) | 2016-12-28 | 2018-07-05 | Sanbio, Inc. | Cell delivery system and methods of operation thereof |
CN109609456B (zh) * | 2018-12-21 | 2022-06-21 | 首都医科大学附属北京潞河医院 | 一种雪旺细胞来源外泌体的用途、诱导剂和试剂盒 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6165747A (en) * | 1993-12-30 | 2000-12-26 | President & Fellows Of Harvard College | Nucleic acids encoding hedgehog proteins |
US5849585A (en) * | 1995-05-10 | 1998-12-15 | Genetech, Inc. | Isolating and culturing Schwann cells |
US5714385A (en) * | 1995-05-10 | 1998-02-03 | Genentech, Inc. | Media for culturing schwann cells |
JP5943533B2 (ja) * | 2000-05-17 | 2016-07-06 | アステリアス バイオセラピューティクス インコーポレイテッド | 神経前駆細胞の集団 |
US6543819B2 (en) * | 2001-04-02 | 2003-04-08 | John Hakimain | Necktie knotter |
US20030220280A1 (en) * | 2002-02-07 | 2003-11-27 | Bunge Mary Bartlett | Schwann cell bridge implants and phosphodiesterase inhibitors to stimulate CNS nerve regeneration |
-
2001
- 2001-06-22 JP JP2001190251A patent/JP3886346B2/ja not_active Expired - Lifetime
-
2002
- 2002-06-21 AT AT02738782T patent/ATE524542T1/de not_active IP Right Cessation
- 2002-06-21 EP EP20110161323 patent/EP2345715A3/de not_active Ceased
- 2002-06-21 EP EP02738782A patent/EP1405906B1/de not_active Expired - Lifetime
- 2002-06-21 US US10/481,603 patent/US6989271B2/en not_active Expired - Lifetime
- 2002-06-21 WO PCT/JP2002/006249 patent/WO2003000871A1/ja active Application Filing
- 2002-06-21 CA CA002450789A patent/CA2450789C/en not_active Expired - Fee Related
- 2002-06-21 ES ES02738782T patent/ES2369259T3/es not_active Expired - Lifetime
- 2002-06-21 DK DK02738782.8T patent/DK1405906T3/da active
-
2005
- 2005-07-19 US US11/183,869 patent/US20050255593A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2450789C (en) | 2007-09-04 |
US20050255593A1 (en) | 2005-11-17 |
EP2345715A2 (de) | 2011-07-20 |
US6989271B2 (en) | 2006-01-24 |
ES2369259T3 (es) | 2011-11-28 |
EP1405906A1 (de) | 2004-04-07 |
EP1405906B1 (de) | 2011-09-14 |
DK1405906T3 (da) | 2011-12-12 |
CA2450789A1 (en) | 2003-01-03 |
US20040197309A1 (en) | 2004-10-07 |
JP3886346B2 (ja) | 2007-02-28 |
WO2003000871A1 (fr) | 2003-01-03 |
EP2345715A3 (de) | 2013-02-13 |
JP2003061647A (ja) | 2003-03-04 |
EP1405906A4 (de) | 2008-03-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |