ATE523602T1 - Mit durch antipsychotika induzierten extrapyramidalen symptomen assoziierte rgs2- genotypen - Google Patents
Mit durch antipsychotika induzierten extrapyramidalen symptomen assoziierte rgs2- genotypenInfo
- Publication number
- ATE523602T1 ATE523602T1 AT07736444T AT07736444T ATE523602T1 AT E523602 T1 ATE523602 T1 AT E523602T1 AT 07736444 T AT07736444 T AT 07736444T AT 07736444 T AT07736444 T AT 07736444T AT E523602 T1 ATE523602 T1 AT E523602T1
- Authority
- AT
- Austria
- Prior art keywords
- extrapyramidal symptoms
- rgs2
- antipsychotics
- genotypes associated
- symptoms induced
- Prior art date
Links
- 208000027776 Extrapyramidal disease Diseases 0.000 title abstract 4
- 239000000164 antipsychotic agent Substances 0.000 title abstract 3
- 102100021258 Regulator of G-protein signaling 2 Human genes 0.000 title 1
- 101710140412 Regulator of G-protein signaling 2 Proteins 0.000 title 1
- 229940005529 antipsychotics Drugs 0.000 title 1
- 101150067744 Rgs2 gene Proteins 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 102000054765 polymorphisms of proteins Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81259906P | 2006-06-12 | 2006-06-12 | |
| PCT/IL2007/000704 WO2007144874A1 (en) | 2006-06-12 | 2007-06-12 | Rgs2 genotypes associated with extrapyramidal symptoms induced by antipsychotic medication |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE523602T1 true ATE523602T1 (de) | 2011-09-15 |
Family
ID=38461906
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07736444T ATE523602T1 (de) | 2006-06-12 | 2007-06-12 | Mit durch antipsychotika induzierten extrapyramidalen symptomen assoziierte rgs2- genotypen |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US20100021891A1 (de) |
| EP (1) | EP2041304B1 (de) |
| AT (1) | ATE523602T1 (de) |
| WO (1) | WO2007144874A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE523602T1 (de) * | 2006-06-12 | 2011-09-15 | Hadasit Med Res Service | Mit durch antipsychotika induzierten extrapyramidalen symptomen assoziierte rgs2- genotypen |
| WO2011148379A2 (en) * | 2010-05-27 | 2011-12-01 | Hadasit Medical Research Services And Development Ltd. | Antipsychotic-induced parkinsonism genotypes and methods of using same |
| US20130080182A1 (en) * | 2011-09-26 | 2013-03-28 | Athleticode Inc. | Methods For Using DNA Testing To Screen For Genotypes Relevant To Athleticism, Health And Risk Of Injury |
| BR112015017815B1 (pt) * | 2013-01-25 | 2022-06-14 | Institut D'investigacions Biomèdiques August Pi I Sunyer | Método para prever o início dos sintomas extrapiramidais (eps) induzidos por um tratamento a base de antipsicótico |
| US10036247B2 (en) * | 2015-11-16 | 2018-07-31 | Baker Hughes, A Ge Company, Llc | Downhole fiber optic measurement of packers during fluid injection operations |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3539573A (en) * | 1967-03-22 | 1970-11-10 | Jean Schmutz | 11-basic substituted dibenzodiazepines and dibenzothiazepines |
| US4086350A (en) * | 1974-11-06 | 1978-04-25 | Smithkline Corporation | Pharmaceutical compositions and method of producing anti-psychotic activity without extrapyramidal symptoms |
| US4458066A (en) * | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
| US4804663A (en) * | 1985-03-27 | 1989-02-14 | Janssen Pharmaceutica N.V. | 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles |
| IE58370B1 (en) * | 1985-04-10 | 1993-09-08 | Lundbeck & Co As H | Indole derivatives |
| US5348855A (en) * | 1986-03-05 | 1994-09-20 | Miles Inc. | Assay for nucleic acid sequences in an unpurified sample |
| GB8607684D0 (en) * | 1986-03-27 | 1986-04-30 | Ici America Inc | Thiazepine compounds |
| US4831031A (en) * | 1988-01-22 | 1989-05-16 | Pfizer Inc. | Aryl piperazinyl-(C2 or C4) alkylene heterocyclic compounds having neuroleptic activity |
| DE68928853T2 (de) | 1988-05-20 | 1999-08-05 | Cetus Corp., Emeryville, Calif. | Befestigung von sequenzspezifischen proben |
| US5006528A (en) * | 1988-10-31 | 1991-04-09 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
| US5238945A (en) * | 1989-04-11 | 1993-08-24 | H. Lundbeck A/S | Method of treating psychoses |
| GB8908085D0 (en) * | 1989-04-11 | 1989-05-24 | Lundbeck & Co As H | New therapeutic use |
| US5500343A (en) * | 1990-02-07 | 1996-03-19 | Board Of Regents, The University Of Texas System | Allelic association of the human dopamine(D2) receptor gene in compulsive disorders |
| US5229382A (en) * | 1990-04-25 | 1993-07-20 | Lilly Industries Limited | 2-methyl-thieno-benzodiazepine |
| US5137712A (en) * | 1990-08-31 | 1992-08-11 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Use of s-adenosyl-l-methionine (SAMe) to reverse and/or prevent supersensitivity, tolerance and extrapyramidal side effects induced by neuroleptic treatment |
| US5312925A (en) * | 1992-09-01 | 1994-05-17 | Pfizer Inc. | Monohydrate of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2H-indol-2-one-hydrochloride |
| US5593840A (en) * | 1993-01-27 | 1997-01-14 | Oncor, Inc. | Amplification of nucleic acid sequences |
| US5324401A (en) * | 1993-02-05 | 1994-06-28 | Iowa State University Research Foundation, Inc. | Multiplexed fluorescence detector system for capillary electrophoresis |
| US6951721B2 (en) * | 1996-02-12 | 2005-10-04 | Gene Logic Inc. | Method for determining the haplotype of a human BRCA1 gene |
| US6844154B2 (en) * | 2000-04-04 | 2005-01-18 | Polygenyx, Inc. | High throughput methods for haplotyping |
| AU2001255448A1 (en) | 2000-04-17 | 2001-10-30 | Stephen B. Liggett | Alpha-2 adrenergic receptor polymorphisms |
| MY129350A (en) * | 2001-04-25 | 2007-03-30 | Bristol Myers Squibb Co | Aripiprazole oral solution |
| EP1425023A1 (de) * | 2001-08-10 | 2004-06-09 | Wyeth | G-proteingekoppelter rezeptor-assay |
| EP1692503B1 (de) | 2003-10-17 | 2009-09-30 | Tata Institute of Fundamental Research | Neuer test zum screening von antipsychotika |
| ATE523602T1 (de) | 2006-06-12 | 2011-09-15 | Hadasit Med Res Service | Mit durch antipsychotika induzierten extrapyramidalen symptomen assoziierte rgs2- genotypen |
| US20090307180A1 (en) | 2008-03-19 | 2009-12-10 | Brandon Colby | Genetic analysis |
-
2007
- 2007-06-12 AT AT07736444T patent/ATE523602T1/de not_active IP Right Cessation
- 2007-06-12 US US12/304,430 patent/US20100021891A1/en not_active Abandoned
- 2007-06-12 EP EP07736444A patent/EP2041304B1/de not_active Not-in-force
- 2007-06-12 WO PCT/IL2007/000704 patent/WO2007144874A1/en not_active Ceased
-
2011
- 2011-06-07 US US13/155,199 patent/US8986929B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20100021891A1 (en) | 2010-01-28 |
| EP2041304B1 (de) | 2011-09-07 |
| US8986929B2 (en) | 2015-03-24 |
| US20110236896A1 (en) | 2011-09-29 |
| EP2041304A1 (de) | 2009-04-01 |
| WO2007144874A1 (en) | 2007-12-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |