ATE520789T1 - Verfahren zur reduzierung des stotterns bei der mikrosatellitenamplifikation - Google Patents
Verfahren zur reduzierung des stotterns bei der mikrosatellitenamplifikationInfo
- Publication number
- ATE520789T1 ATE520789T1 AT02734201T AT02734201T ATE520789T1 AT E520789 T1 ATE520789 T1 AT E520789T1 AT 02734201 T AT02734201 T AT 02734201T AT 02734201 T AT02734201 T AT 02734201T AT E520789 T1 ATE520789 T1 AT E520789T1
- Authority
- AT
- Austria
- Prior art keywords
- microsatellite
- sorbitol
- sample
- betaine
- amount
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6846—Common amplification features
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/850,514 US6841349B2 (en) | 2001-05-07 | 2001-05-07 | Methods for the reduction of stutter in microsatellite amplification |
| PCT/US2002/014189 WO2002090562A2 (en) | 2001-05-07 | 2002-05-06 | Methods for the reduction of stutter in microsatellite amplification |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE520789T1 true ATE520789T1 (de) | 2011-09-15 |
Family
ID=25308342
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02734201T ATE520789T1 (de) | 2001-05-07 | 2002-05-06 | Verfahren zur reduzierung des stotterns bei der mikrosatellitenamplifikation |
Country Status (6)
| Country | Link |
|---|---|
| US (6) | US6841349B2 (de) |
| EP (2) | EP1476560B1 (de) |
| JP (1) | JP2005514902A (de) |
| AT (1) | ATE520789T1 (de) |
| CA (1) | CA2446626A1 (de) |
| WO (1) | WO2002090562A2 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6841349B2 (en) | 2001-05-07 | 2005-01-11 | Applera Corporation Applied Biosystems Group | Methods for the reduction of stutter in microsatellite amplification |
| PL1842533T3 (pl) * | 2003-08-06 | 2013-08-30 | Gruenenthal Gmbh | Postać aplikacyjna zabezpieczona przed nadużyciem |
| US20050112591A1 (en) * | 2003-11-25 | 2005-05-26 | Applera Corporation | Novel method for isolating single stranded product |
| US20090004662A1 (en) * | 2007-06-18 | 2009-01-01 | Applera Corporation | Method and compositions for nucleic acid amplification |
| US20090023138A1 (en) * | 2007-07-17 | 2009-01-22 | Zila Biotechnology, Inc. | Oral cancer markers and their detection |
| GB2472371B (en) * | 2009-04-24 | 2011-10-26 | Selectamark Security Systems Plc | Synthetic nucleotide containing compositions for use in security marking of property and/or for marking a thief or attacker |
| EP3642354B1 (de) | 2017-06-20 | 2022-08-03 | Bio-Rad Laboratories, Inc. | Digitale amplifikationsassays für genetische instabilität |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03503762A (ja) * | 1989-02-15 | 1991-08-22 | ナチュラル ホワイト インコーポレイテッド | 歯のホワイトナー |
| US5571674A (en) | 1989-09-18 | 1996-11-05 | The Trustees Of Columbia University In The City Of New York | DNA oligomers for use in detection of campylobacter pylori and methods of using such DNA oligomers |
| US5606045A (en) | 1990-05-15 | 1997-02-25 | Diatron Corporation | Nucleic acid probes and methods |
| IE913930A1 (en) | 1990-11-13 | 1992-06-17 | Siska Diagnostics | Nucleic acid amplification by two-enzyme, self-sustained¹sequence replication |
| US5364759B2 (en) | 1991-01-31 | 1999-07-20 | Baylor College Medicine | Dna typing with short tandem repeat polymorphisms and identification of polymorphic short tandem repeats |
| DE4411588C1 (de) | 1994-03-30 | 1995-09-28 | Deutsches Rheuma Forschungszen | Puffer für DNA- und RNA-Polymerase-Reaktionen |
| US5580728A (en) | 1994-06-17 | 1996-12-03 | Perlin; Mark W. | Method and system for genotyping |
| WO1996006951A1 (en) | 1994-08-31 | 1996-03-07 | The Johns Hopkins University School Of Medicine | Detection of hypermutable nucleic acid sequence in tissue |
| US5545539A (en) | 1994-10-18 | 1996-08-13 | Genzyme Corporation | Method for nucleotide sequence amplification |
| US6077664A (en) | 1995-06-07 | 2000-06-20 | Promega Corporation | Thermophilic DNA polymerases from Thermotoga neapolitana |
| US6114150A (en) | 1995-11-29 | 2000-09-05 | Yale University | Amplification of nucleic acids |
| AU722327B2 (en) * | 1996-04-19 | 2000-07-27 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Method of stimulating an immune response by administration of host organisms that express intimin alone or as a fusion protein with one or more other antigens |
| US6156512A (en) | 1996-05-23 | 2000-12-05 | Promega Corp | Allelic ladders for short tandem repeat loci |
| US6787305B1 (en) | 1998-03-13 | 2004-09-07 | Invitrogen Corporation | Compositions and methods for enhanced synthesis of nucleic acid molecules |
| JP4438110B2 (ja) | 1998-07-01 | 2010-03-24 | 東ソー株式会社 | 標的核酸の定量方法 |
| GB9823005D0 (en) | 1998-10-22 | 1998-12-16 | Harbron Stuart | Detection of amplified products in nucleic acid assays |
| US6153412A (en) * | 1998-12-07 | 2000-11-28 | Bioneer Corporation | Lyophilized reagent for polymerase chain reaction |
| EP1103624A4 (de) | 1999-06-04 | 2004-12-22 | Tosoh Corp | Verbessertes verfahren zur amplifikation von nukleinsäuren |
| US6841349B2 (en) * | 2001-05-07 | 2005-01-11 | Applera Corporation Applied Biosystems Group | Methods for the reduction of stutter in microsatellite amplification |
| US6780588B2 (en) | 2001-05-07 | 2004-08-24 | Applera Corporation | Methods for the reduction of stutter in microsatellite amplification |
| US6783940B2 (en) | 2001-10-31 | 2004-08-31 | Applera Corporation | Method of reducing non-specific amplification in PCR |
| US7875274B2 (en) | 2005-12-16 | 2011-01-25 | The Board Of Trustees Of The Leland Stanford Junior University | Protein modulators of resistance to alkylating agents |
-
2001
- 2001-05-07 US US09/850,514 patent/US6841349B2/en not_active Expired - Lifetime
-
2002
- 2002-05-06 AT AT02734201T patent/ATE520789T1/de not_active IP Right Cessation
- 2002-05-06 EP EP02734201A patent/EP1476560B1/de not_active Expired - Lifetime
- 2002-05-06 CA CA002446626A patent/CA2446626A1/en not_active Abandoned
- 2002-05-06 JP JP2002587621A patent/JP2005514902A/ja not_active Withdrawn
- 2002-05-06 EP EP10184294.6A patent/EP2325325B1/de not_active Expired - Lifetime
- 2002-05-06 WO PCT/US2002/014189 patent/WO2002090562A2/en active Application Filing
-
2003
- 2003-08-08 US US10/637,466 patent/US7211385B2/en not_active Expired - Lifetime
-
2007
- 2007-04-30 US US11/742,524 patent/US20080213859A1/en not_active Abandoned
-
2010
- 2010-04-28 US US12/769,577 patent/US20110143352A1/en not_active Abandoned
-
2012
- 2012-09-12 US US13/611,974 patent/US8785126B2/en not_active Expired - Fee Related
-
2014
- 2014-06-30 US US14/320,095 patent/US20150024387A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002090562A2 (en) | 2002-11-14 |
| US20130011839A1 (en) | 2013-01-10 |
| US20030044786A1 (en) | 2003-03-06 |
| US8785126B2 (en) | 2014-07-22 |
| US20080213859A1 (en) | 2008-09-04 |
| EP2325325A1 (de) | 2011-05-25 |
| US7211385B2 (en) | 2007-05-01 |
| EP2325325B1 (de) | 2013-12-11 |
| CA2446626A1 (en) | 2002-11-14 |
| WO2002090562A3 (en) | 2004-08-26 |
| EP1476560A4 (de) | 2005-05-04 |
| US6841349B2 (en) | 2005-01-11 |
| US20110143352A1 (en) | 2011-06-16 |
| EP1476560B1 (de) | 2011-08-17 |
| US20050037361A1 (en) | 2005-02-17 |
| EP1476560A2 (de) | 2004-11-17 |
| US20150024387A1 (en) | 2015-01-22 |
| JP2005514902A (ja) | 2005-05-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |