ATE520666T1 - Derivate von 18-amino-substituierten analoga des geldamycin-hydrochinons mit cyctotoxischer wirkung für die behandlung von krebs - Google Patents
Derivate von 18-amino-substituierten analoga des geldamycin-hydrochinons mit cyctotoxischer wirkung für die behandlung von krebsInfo
- Publication number
- ATE520666T1 ATE520666T1 AT07854639T AT07854639T ATE520666T1 AT E520666 T1 ATE520666 T1 AT E520666T1 AT 07854639 T AT07854639 T AT 07854639T AT 07854639 T AT07854639 T AT 07854639T AT E520666 T1 ATE520666 T1 AT E520666T1
- Authority
- AT
- Austria
- Prior art keywords
- hydrocinone
- geldamycin
- cyctotoxic
- cancer
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
- C07D225/04—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D225/06—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86597706P | 2006-11-15 | 2006-11-15 | |
| PCT/US2007/084662 WO2008061134A1 (en) | 2006-11-15 | 2007-11-14 | Derivatives of 18-amino substituted analogs of the geldamycin hydroquinon with cytotoxic activity for the treatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE520666T1 true ATE520666T1 (de) | 2011-09-15 |
Family
ID=39106113
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07854639T ATE520666T1 (de) | 2006-11-15 | 2007-11-14 | Derivate von 18-amino-substituierten analoga des geldamycin-hydrochinons mit cyctotoxischer wirkung für die behandlung von krebs |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7816346B2 (de) |
| EP (1) | EP2091919B1 (de) |
| AT (1) | ATE520666T1 (de) |
| CA (1) | CA2669820A1 (de) |
| CY (1) | CY1112755T1 (de) |
| DK (1) | DK2091919T3 (de) |
| ES (1) | ES2367876T3 (de) |
| PL (1) | PL2091919T3 (de) |
| PT (1) | PT2091919E (de) |
| SI (1) | SI2091919T1 (de) |
| WO (1) | WO2008061134A1 (de) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3987035A (en) * | 1974-04-05 | 1976-10-19 | University Of Illinois Foundation | Biologically active compounds |
| CA2146668A1 (en) * | 1992-10-14 | 1994-04-28 | Luke Whitesell | Tumoricidal activity of benzoquinonoid ansamycins against prostate cancer and primitive neural malignancies |
| US6537579B1 (en) * | 1993-02-22 | 2003-03-25 | American Bioscience, Inc. | Compositions and methods for administration of pharmacologically active compounds |
| US6096331A (en) * | 1993-02-22 | 2000-08-01 | Vivorx Pharmaceuticals, Inc. | Methods and compositions useful for administration of chemotherapeutic agents |
| US5916596A (en) * | 1993-02-22 | 1999-06-29 | Vivorx Pharmaceuticals, Inc. | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof |
-
2007
- 2007-11-14 PL PL07854639T patent/PL2091919T3/pl unknown
- 2007-11-14 WO PCT/US2007/084662 patent/WO2008061134A1/en active Application Filing
- 2007-11-14 AT AT07854639T patent/ATE520666T1/de active
- 2007-11-14 PT PT07854639T patent/PT2091919E/pt unknown
- 2007-11-14 DK DK07854639.7T patent/DK2091919T3/da active
- 2007-11-14 ES ES07854639T patent/ES2367876T3/es active Active
- 2007-11-14 SI SI200730759T patent/SI2091919T1/sl unknown
- 2007-11-14 EP EP07854639A patent/EP2091919B1/de active Active
- 2007-11-14 CA CA002669820A patent/CA2669820A1/en not_active Abandoned
- 2007-11-15 US US11/940,644 patent/US7816346B2/en not_active Expired - Fee Related
-
2011
- 2011-09-20 CY CY20111100907T patent/CY1112755T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2091919B1 (de) | 2011-08-17 |
| WO2008061134A1 (en) | 2008-05-22 |
| US20080234246A1 (en) | 2008-09-25 |
| EP2091919A1 (de) | 2009-08-26 |
| CY1112755T1 (el) | 2016-02-10 |
| DK2091919T3 (da) | 2011-12-05 |
| US7816346B2 (en) | 2010-10-19 |
| ES2367876T3 (es) | 2011-11-10 |
| CA2669820A1 (en) | 2008-05-22 |
| SI2091919T1 (sl) | 2011-12-30 |
| PT2091919E (pt) | 2011-09-05 |
| PL2091919T3 (pl) | 2011-12-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1122984T1 (el) | Καρβαμιδικες ενωσεις και μεθοδοι παρασκευης και χρησης τους | |
| MX2020002183A (es) | Inhibidores de la ectonucleótido pirofosfatasa-fosfodiesterasa 1 (enpp-1) y usos de los mismos. | |
| CY1123810T1 (el) | Τριφθορομεθυλ υποκατεστημενα πυραζολια ως αναστολεις καλλικρεϊνης στο ανθρωπινο πλασμα | |
| CY1121125T1 (el) | Συνθεσεις για τη θεραπευτικη αντιμετωπιση του πονου και/ή της φλεγμονης | |
| CY1123666T1 (el) | Φαρμακευτικες ενωσεις | |
| LTPA2016016I1 (lt) | Azetinidai kaip mek inhibitoriai, skirti proliferacinių ligų gydymui | |
| EA201690265A2 (ru) | Фармацевтические композиции, содержащие замещенные ациланилиды | |
| BR112015011497A2 (pt) | composto, formulação farmacêutica, produto de combinação, e, método de tratamento de uma doença | |
| MX2020011234A (es) | Moduladores de receptor similar al dominio de oligomerizacion de union a nucleotidos que contiene dominio de pirina 3 (nlrp3). | |
| GEP20237519B (en) | Aza-heterobicyclic inhibitors of mat2a and methods of use for treating cancer | |
| NO20091661L (no) | Anvendelse av pegylert IL-10 for a behandle kreft | |
| DK1519724T3 (da) | Fredericamycin-derivater som lægemidler til behandling af tumorer | |
| UA109878C2 (uk) | Похідні ізохінолінону, фармацевтична композиція на їх основі (варіанти) та спосіб лікування захворювань (варіанти) | |
| GEP20227443B (en) | Magl inhibitors | |
| EA201391720A1 (ru) | Замещенные диоксопиперидинилфталимидные производные | |
| EA200800555A1 (ru) | Производные ксантина в качестве селективных агонистов hm74a | |
| CY1125150T1 (el) | Ενωσεις φαινυλο-2-υδροξυ-ακετυλαμινο-2-μεθυλο-φαινυλιου | |
| DE50310516D1 (de) | Fredericamycin-derivate | |
| EA201001747A1 (ru) | Бензоксазиноновые производные, действующие в качестве агониста бета-2-адренорецептора, для лечения респираторных расстройств | |
| EA201001196A1 (ru) | Соединения 4-пиридинона и их применение для лечения рака | |
| MX2022006768A (es) | Formulaciones/composiciones que comprenden un inhibidor de btk. | |
| CY1116840T1 (el) | Χρηση 24-norudca | |
| EA201170344A1 (ru) | Азаиндольные ингибиторы iap | |
| CY1110027T1 (el) | Συνδυασμος ενωσεων πυριμιδυλαμινοβενζαμιδης και ιματινιβης για τη θεραπεια ή την προληψη των νεοπλασματικων ασθενειων | |
| MX2020011826A (es) | Composiciones de combinacion que comprenden compuestos de bisfluoroalquil-1,4-benzodiazepinona y metodos de uso de las mismas. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 2091919 Country of ref document: EP |