DK2091919T3 - Derivater af 18-amino-substituerede analoge af geldamycinhydroquinon med cytotoksisk aktivitet til behandling af cancer - Google Patents
Derivater af 18-amino-substituerede analoge af geldamycinhydroquinon med cytotoksisk aktivitet til behandling af cancerInfo
- Publication number
- DK2091919T3 DK2091919T3 DK07854639.7T DK07854639T DK2091919T3 DK 2091919 T3 DK2091919 T3 DK 2091919T3 DK 07854639 T DK07854639 T DK 07854639T DK 2091919 T3 DK2091919 T3 DK 2091919T3
- Authority
- DK
- Denmark
- Prior art keywords
- geldamycin
- hydroquinone
- cancer
- derivatives
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
- C07D225/04—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D225/06—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86597706P | 2006-11-15 | 2006-11-15 | |
| PCT/US2007/084662 WO2008061134A1 (en) | 2006-11-15 | 2007-11-14 | Derivatives of 18-amino substituted analogs of the geldamycin hydroquinon with cytotoxic activity for the treatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2091919T3 true DK2091919T3 (da) | 2011-12-05 |
Family
ID=39106113
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07854639.7T DK2091919T3 (da) | 2006-11-15 | 2007-11-14 | Derivater af 18-amino-substituerede analoge af geldamycinhydroquinon med cytotoksisk aktivitet til behandling af cancer |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7816346B2 (da) |
| EP (1) | EP2091919B1 (da) |
| AT (1) | ATE520666T1 (da) |
| CA (1) | CA2669820A1 (da) |
| CY (1) | CY1112755T1 (da) |
| DK (1) | DK2091919T3 (da) |
| ES (1) | ES2367876T3 (da) |
| PL (1) | PL2091919T3 (da) |
| PT (1) | PT2091919E (da) |
| SI (1) | SI2091919T1 (da) |
| WO (1) | WO2008061134A1 (da) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3987035A (en) * | 1974-04-05 | 1976-10-19 | University Of Illinois Foundation | Biologically active compounds |
| EP0664702A1 (en) * | 1992-10-14 | 1995-08-02 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | Tumoricidal activity of benzoquinonoid ansamycins against prostate cancer and primitive neural malignancies |
| US6537579B1 (en) * | 1993-02-22 | 2003-03-25 | American Bioscience, Inc. | Compositions and methods for administration of pharmacologically active compounds |
| US5916596A (en) * | 1993-02-22 | 1999-06-29 | Vivorx Pharmaceuticals, Inc. | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof |
| US6096331A (en) * | 1993-02-22 | 2000-08-01 | Vivorx Pharmaceuticals, Inc. | Methods and compositions useful for administration of chemotherapeutic agents |
-
2007
- 2007-11-14 ES ES07854639T patent/ES2367876T3/es active Active
- 2007-11-14 EP EP07854639A patent/EP2091919B1/en active Active
- 2007-11-14 DK DK07854639.7T patent/DK2091919T3/da active
- 2007-11-14 AT AT07854639T patent/ATE520666T1/de active
- 2007-11-14 SI SI200730759T patent/SI2091919T1/sl unknown
- 2007-11-14 PL PL07854639T patent/PL2091919T3/pl unknown
- 2007-11-14 PT PT07854639T patent/PT2091919E/pt unknown
- 2007-11-14 WO PCT/US2007/084662 patent/WO2008061134A1/en active Application Filing
- 2007-11-14 CA CA002669820A patent/CA2669820A1/en not_active Abandoned
- 2007-11-15 US US11/940,644 patent/US7816346B2/en not_active Expired - Fee Related
-
2011
- 2011-09-20 CY CY20111100907T patent/CY1112755T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2091919B1 (en) | 2011-08-17 |
| WO2008061134A1 (en) | 2008-05-22 |
| PT2091919E (pt) | 2011-09-05 |
| US20080234246A1 (en) | 2008-09-25 |
| ATE520666T1 (de) | 2011-09-15 |
| US7816346B2 (en) | 2010-10-19 |
| ES2367876T3 (es) | 2011-11-10 |
| EP2091919A1 (en) | 2009-08-26 |
| CY1112755T1 (el) | 2016-02-10 |
| SI2091919T1 (sl) | 2011-12-30 |
| CA2669820A1 (en) | 2008-05-22 |
| PL2091919T3 (pl) | 2011-12-30 |
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