ATE51224T1 - Chinolon-inotropische mittel. - Google Patents
Chinolon-inotropische mittel.Info
- Publication number
- ATE51224T1 ATE51224T1 AT86300524T AT86300524T ATE51224T1 AT E51224 T1 ATE51224 T1 AT E51224T1 AT 86300524 T AT86300524 T AT 86300524T AT 86300524 T AT86300524 T AT 86300524T AT E51224 T1 ATE51224 T1 AT E51224T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- het
- heterocyclic group
- attached
- conr
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB858502267A GB8502267D0 (en) | 1985-01-30 | 1985-01-30 | Quinolone inotropic agents |
| CN85104392A CN85104392B (zh) | 1985-01-30 | 1985-06-10 | 喹诺酮变力剂的制备方法 |
| EP86300524A EP0190857B1 (de) | 1985-01-30 | 1986-01-27 | Chinolon-inotropische Mittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE51224T1 true ATE51224T1 (de) | 1990-04-15 |
Family
ID=25741743
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86300524T ATE51224T1 (de) | 1985-01-30 | 1986-01-27 | Chinolon-inotropische mittel. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4728654A (de) |
| EP (1) | EP0190857B1 (de) |
| JP (1) | JPS61176568A (de) |
| KR (1) | KR880000132B1 (de) |
| CN (1) | CN85104392B (de) |
| AT (1) | ATE51224T1 (de) |
| AU (1) | AU557667B2 (de) |
| CA (1) | CA1255662A (de) |
| DE (1) | DE3669714D1 (de) |
| DK (1) | DK43286A (de) |
| ES (2) | ES8706122A1 (de) |
| FI (1) | FI860424A7 (de) |
| GB (1) | GB8502267D0 (de) |
| GR (1) | GR860249B (de) |
| HU (1) | HU194831B (de) |
| IE (1) | IE860258L (de) |
| PL (1) | PL257669A1 (de) |
| PT (1) | PT81921B (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4582909A (en) * | 1984-02-02 | 1986-04-15 | Warner-Lambert Company | Benzobicyclic lactam acids and derivatives as cognition activators |
| US4797490A (en) * | 1984-12-06 | 1989-01-10 | Pfizer Inc. | Process for the preparation of 3-(2'-fluorophenyl)pyridine |
| GB8709448D0 (en) * | 1987-04-21 | 1987-05-28 | Pfizer Ltd | Heterobicyclic quinoline derivatives |
| JP2686887B2 (ja) * | 1992-08-11 | 1997-12-08 | キッセイ薬品工業株式会社 | ピペリジノ−３，４−ジヒドロカルボスチリル誘導体 |
| MY146795A (en) * | 2005-06-09 | 2012-09-28 | Novartis Ag | Process for the synthesis of organic compounds |
| CN102532015B (zh) * | 2012-01-18 | 2013-10-23 | 云南大学 | 香豆素及其类似物的固相合成方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3287459A (en) * | 1961-10-23 | 1966-11-22 | Chattanooga Medicine Co | Carbostyrils, coumarines and thiocoumarines |
| US3668207A (en) * | 1970-01-22 | 1972-06-06 | Ciba Geigy Corp | 2-amino-4-aryl-quinolines |
| BE884459Q (fr) * | 1971-05-14 | 1981-01-26 | Boehringer Mannheim Gmbh | Derives de la 4-(omega-(coumarine-7-yl-oxy)-alkyl)-piperazine et procede de preparation |
| DE2123923A1 (de) * | 1971-05-14 | 1972-11-23 | Boehringer Mannheim Gmbh, 6800 Mannheim | 4-eckige Klammer auf omega- (Flavon-7yl-oxy) -alkyl eckige Klammer zu -pigerazin-Derivate und Verfahren zu ihrer Herstellung |
| JPS4976877A (de) * | 1972-11-28 | 1974-07-24 | ||
| US4004012A (en) * | 1975-10-14 | 1977-01-18 | Sterling Drug Inc. | 3-Cyano-5-(pyridinyl)-2(1H)-pyridinones |
| DE2827566A1 (de) * | 1978-06-23 | 1980-01-10 | Boehringer Mannheim Gmbh | 1,2-dihydro-chinolin-2-on-derivate und verfahren zu ihrer herstellung |
| HU190412B (en) * | 1981-09-17 | 1986-09-29 | Warner-Lambert Co,Us | Process for producing substituted 4,5-dihiydro-6-bracket-substituted-bracket closed-phenyl-3-bracket-2h-bracket closed-pyridazinones and 6-bracket-substituted-bracket closed-phenyl-3-bracket-2h-bracket closed-pyridazinones |
| IL69407A (en) * | 1982-08-23 | 1987-10-20 | Warner Lambert Co | 2(1h)-pyridinones,their preparation and pharmaceutical compositions containing them |
| US4503061A (en) * | 1983-07-22 | 1985-03-05 | Warner-Lambert Company | Substituted phenyl-pyridinones as cardiotonic agents |
| US4550119A (en) * | 1983-05-23 | 1985-10-29 | Warner-Lambert Company | 2,4-Dihydro-5-[(substituted)phenyl]-4,4-disubstituted-3H-pyrazol-3-ones |
| PT79699B (en) * | 1983-12-22 | 1986-12-10 | Pfizer | Process for preparing quinolone inotropic agents |
| NZ212209A (en) * | 1984-05-29 | 1988-08-30 | Pfizer | Quinolone derivatives and pharmaceutical compositions |
-
1985
- 1985-01-30 GB GB858502267A patent/GB8502267D0/en active Pending
- 1985-06-10 CN CN85104392A patent/CN85104392B/zh not_active Expired
-
1986
- 1986-01-27 EP EP86300524A patent/EP0190857B1/de not_active Expired - Lifetime
- 1986-01-27 US US06/822,575 patent/US4728654A/en not_active Expired - Lifetime
- 1986-01-27 DE DE8686300524T patent/DE3669714D1/de not_active Expired - Lifetime
- 1986-01-27 AT AT86300524T patent/ATE51224T1/de not_active IP Right Cessation
- 1986-01-28 GR GR860249A patent/GR860249B/el unknown
- 1986-01-28 CA CA000500469A patent/CA1255662A/en not_active Expired
- 1986-01-28 PT PT81921A patent/PT81921B/pt unknown
- 1986-01-28 PL PL25766986A patent/PL257669A1/xx unknown
- 1986-01-28 ES ES551343A patent/ES8706122A1/es not_active Expired
- 1986-01-29 FI FI860424A patent/FI860424A7/fi not_active Application Discontinuation
- 1986-01-29 HU HU86408A patent/HU194831B/hu not_active IP Right Cessation
- 1986-01-29 KR KR1019860000571A patent/KR880000132B1/ko not_active Expired
- 1986-01-29 IE IE860258A patent/IE860258L/xx unknown
- 1986-01-29 AU AU52798/86A patent/AU557667B2/en not_active Ceased
- 1986-01-29 DK DK43286A patent/DK43286A/da not_active Application Discontinuation
- 1986-01-30 JP JP61019171A patent/JPS61176568A/ja active Pending
-
1987
- 1987-02-27 ES ES557430A patent/ES8801902A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| KR860005790A (ko) | 1986-08-13 |
| EP0190857A3 (en) | 1987-08-19 |
| KR880000132B1 (ko) | 1988-03-12 |
| ES557430A0 (es) | 1988-03-01 |
| PT81921B (en) | 1987-11-16 |
| ES8801902A1 (es) | 1988-03-01 |
| AU5279886A (en) | 1986-08-07 |
| US4728654A (en) | 1988-03-01 |
| JPS61176568A (ja) | 1986-08-08 |
| DE3669714D1 (de) | 1990-04-26 |
| PL257669A1 (en) | 1987-05-18 |
| IE860258L (en) | 1986-07-30 |
| ES8706122A1 (es) | 1987-06-01 |
| HUT40421A (en) | 1986-12-28 |
| FI860424A0 (fi) | 1986-01-29 |
| DK43286A (da) | 1986-07-31 |
| EP0190857B1 (de) | 1990-03-21 |
| PT81921A (en) | 1986-02-01 |
| DK43286D0 (da) | 1986-01-29 |
| CN85104392B (zh) | 1988-02-17 |
| EP0190857A2 (de) | 1986-08-13 |
| GB8502267D0 (en) | 1985-02-27 |
| CA1255662A (en) | 1989-06-13 |
| FI860424A7 (fi) | 1986-07-31 |
| CN85104392A (zh) | 1986-12-24 |
| AU557667B2 (en) | 1987-01-08 |
| ES551343A0 (es) | 1987-06-01 |
| HU194831B (en) | 1988-03-28 |
| GR860249B (en) | 1986-05-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU555083B2 (en) | Pyridine/biphenyl derivatives | |
| ATE51224T1 (de) | Chinolon-inotropische mittel. | |
| NO922812L (no) | Naftyridin- og kinolizinderivater og farmasoeytiske preparater inneholdende disse |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |