ATE509932T1 - Polymorphe form von 6-(4-chlorphenyl)-2,2- - Google Patents

Polymorphe form von 6-(4-chlorphenyl)-2,2-

Info

Publication number
ATE509932T1
ATE509932T1 AT06723557T AT06723557T ATE509932T1 AT E509932 T1 ATE509932 T1 AT E509932T1 AT 06723557 T AT06723557 T AT 06723557T AT 06723557 T AT06723557 T AT 06723557T AT E509932 T1 ATE509932 T1 AT E509932T1
Authority
AT
Austria
Prior art keywords
ppm
chlorphenyl
polymorphous form
pyrrolizin
adamantane
Prior art date
Application number
AT06723557T
Other languages
English (en)
Inventor
Wolfgang Albrecht
Thomas Kammermeier
Hans-Guenter Striegel
Philipp Merckle
Stefan Laufer
Original Assignee
Merckle Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merckle Gmbh filed Critical Merckle Gmbh
Application granted granted Critical
Publication of ATE509932T1 publication Critical patent/ATE509932T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT06723557T 2005-03-21 2006-03-20 Polymorphe form von 6-(4-chlorphenyl)-2,2- ATE509932T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005012971A DE102005012971A1 (de) 2005-03-21 2005-03-21 Polymorphe Form von 6-(4-Chlorphenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl-essigsäure
PCT/EP2006/002539 WO2006100019A1 (en) 2005-03-21 2006-03-20 Polymorphic form of 6- (4-chlorophenyl) -2, 2-dimethyl-7-phenyl-2, 3-dihydro-lh-pyrrolizin-5-ylacetic acid

Publications (1)

Publication Number Publication Date
ATE509932T1 true ATE509932T1 (de) 2011-06-15

Family

ID=36568591

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06723557T ATE509932T1 (de) 2005-03-21 2006-03-20 Polymorphe form von 6-(4-chlorphenyl)-2,2-

Country Status (15)

Country Link
US (1) US8034837B2 (de)
EP (1) EP1861404B1 (de)
JP (1) JP5009280B2 (de)
CN (1) CN101160311B (de)
AT (1) ATE509932T1 (de)
AU (1) AU2006226625B2 (de)
CA (1) CA2602224A1 (de)
DE (1) DE102005012971A1 (de)
ES (1) ES2367274T3 (de)
MX (1) MX2007011455A (de)
PL (1) PL1861404T3 (de)
PT (1) PT1861404E (de)
RU (1) RU2007138924A (de)
SI (1) SI1861404T1 (de)
WO (1) WO2006100019A1 (de)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260451A (en) 1989-05-11 1993-11-09 Merckle Gmbh Substituted pyrrole compounds and use thereof in pharmaceutical compositions
DE3915450A1 (de) 1989-05-11 1990-11-15 Gerd Prof Dr Dannhardt Substituierte pyrrolverbindungen und deren anwendung in der pharmazie
DE4419247A1 (de) 1994-06-01 1995-12-07 Merckle Gmbh Sulfonylierte Pyrrolizincarbonsäureamide und deren Anwendung in der Pharmazie
DE4419246A1 (de) 1994-06-01 1995-12-07 Merckle Gmbh Heteroarylsubstituierte Pyrrolizinverbindungen und deren Anwendung in der Pharmazie
DE4419315A1 (de) 1994-06-01 1995-12-07 Merckle Gmbh Heteropyrrolizinverbindungen und deren Anwendung in der Pharmazie
CA2246265A1 (en) * 1996-02-13 1997-08-21 G.D. Searle & Co. Combinations having immunosuppressive effects, containing cyclooxygenase-2-inhibitors and 5-lipoxygenase inhibitors
SK286608B6 (sk) 2000-01-28 2009-02-05 Merckle Gmbh Spôsob prípravy kyseliny 6-(4-chlórfenyl)-2,2-dimetyl-7-fenyl- 2,3-dihydro-1H-pyrolizin-5-yl octovej
DE10141285A1 (de) 2001-08-23 2003-03-27 Merckle Gmbh Verfahren zur Herstellung von 6-(4-Chlorphenyl)-2,2-dimethyl-7-phnyl-2,3-dihydro-1H-pyrrolizin-5-yl-essigsäure
PL1745791T3 (pl) * 2003-05-07 2013-11-29 Osteologix As Leczenie chorób chrząstki/kości za pomocą rozpuszczalnych w wodzie soli strontu

Also Published As

Publication number Publication date
ES2367274T3 (es) 2011-11-02
RU2007138924A (ru) 2009-04-27
PL1861404T3 (pl) 2011-12-30
MX2007011455A (es) 2007-12-06
DE102005012971A1 (de) 2006-09-28
AU2006226625B2 (en) 2011-04-21
US8034837B2 (en) 2011-10-11
PT1861404E (pt) 2011-09-01
JP2008535809A (ja) 2008-09-04
EP1861404A1 (de) 2007-12-05
AU2006226625A1 (en) 2006-09-28
CN101160311A (zh) 2008-04-09
CN101160311B (zh) 2010-11-24
US20090209610A1 (en) 2009-08-20
SI1861404T1 (sl) 2011-11-30
CA2602224A1 (en) 2006-09-28
EP1861404B1 (de) 2011-05-18
JP5009280B2 (ja) 2012-08-22
WO2006100019A1 (en) 2006-09-28

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