ATE502911T1 - 4-(c2-6 alkoxy)substituierte chalkone als therapeutische mittel - Google Patents
4-(c2-6 alkoxy)substituierte chalkone als therapeutische mittelInfo
- Publication number
- ATE502911T1 ATE502911T1 AT02762611T AT02762611T ATE502911T1 AT E502911 T1 ATE502911 T1 AT E502911T1 AT 02762611 T AT02762611 T AT 02762611T AT 02762611 T AT02762611 T AT 02762611T AT E502911 T1 ATE502911 T1 AT E502911T1
- Authority
- AT
- Austria
- Prior art keywords
- sup
- sub
- optionally substituted
- alkyl
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
- C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0123780.9A GB0123780D0 (en) | 2001-10-03 | 2001-10-03 | Substituted chalcones as therapeutic agents |
PCT/GB2002/004462 WO2003029176A1 (en) | 2001-10-03 | 2002-09-30 | 4-(c2-6alkoxy)-substituted chalcones as therapeutic agents |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE502911T1 true ATE502911T1 (de) | 2011-04-15 |
Family
ID=9923191
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02762611T ATE502911T1 (de) | 2001-10-03 | 2002-09-30 | 4-(c2-6 alkoxy)substituierte chalkone als therapeutische mittel |
Country Status (8)
Country | Link |
---|---|
US (1) | US7112698B2 (de) |
EP (1) | EP1432669B1 (de) |
AT (1) | ATE502911T1 (de) |
CA (1) | CA2462228C (de) |
DE (1) | DE60239548D1 (de) |
ES (1) | ES2364312T3 (de) |
GB (1) | GB0123780D0 (de) |
WO (1) | WO2003029176A1 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080266261A1 (en) * | 2007-04-25 | 2008-10-30 | Idzik Jacek S | Keystroke Error Correction Method |
GB0907551D0 (en) | 2009-05-01 | 2009-06-10 | Univ Dundee | Treatment or prophylaxis of proliferative conditions |
KR20200118827A (ko) | 2018-02-02 | 2020-10-16 | 마베릭스 온콜로지, 잉크. | 젬시타빈 모노포스페이트의 소분자 약물 컨쥬게이트 |
US11746104B2 (en) | 2019-06-13 | 2023-09-05 | Qatar University | Chalcone-based chemotherapeutic compound for triple negative breast cancer |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4279930A (en) | 1978-10-10 | 1981-07-21 | The Upjohn Company | Process for treating inflammation |
JPS6176433A (ja) | 1984-09-21 | 1986-04-18 | Toyobo Co Ltd | 新規なカルコン誘導体 |
LU86715A1 (fr) * | 1986-12-16 | 1988-07-14 | Oreal | Composition cosmetique contenant des derives hydroxyles de chalcone et son utilisation pour la protection de la peau et des cheveux contre les radiations lumineuses,nouveaux derives hydroxyles de chalcone utilises et leur procede de preparation |
JPH02142717A (ja) | 1988-11-22 | 1990-05-31 | Kanebo Ltd | 養毛化粧料 |
JPH05246932A (ja) | 1992-03-04 | 1993-09-24 | Nippon High Potsukusu:Kk | 3,4−ジヒドロキシカルコン誘導体 |
US5430062A (en) | 1992-05-21 | 1995-07-04 | Research Corporation Technologies, Inc. | Stilbene derivatives as anticancer agents |
AU693110B2 (en) | 1993-08-19 | 1998-06-25 | Warner-Lambert Company | Substituted 2(5H)furanone, 2(5H)thiophenone and 2(5H)pyrrolone derivatives, their preparation and their use as endothelin antagonists |
JPH08188546A (ja) * | 1995-01-04 | 1996-07-23 | Kyowa Hakko Kogyo Co Ltd | カルコン誘導体 |
GB9519490D0 (en) | 1995-09-25 | 1995-11-29 | Melvin William T | Use of a cytochrome P450 enzyme in tumour cells as a marker and target |
WO1999000114A2 (en) | 1997-06-26 | 1999-01-07 | Statens Serum Institut | Biologically active 1,3-bis-aromatic-prop-2-en-1-ones, 1,3-bis-aromatic-propan-1-ones, and 1,3-bis-aromatic-prop-2-yn-1-ones |
AU2173899A (en) | 1998-02-06 | 1999-08-23 | De Montfort University | Hydroxylation activated prodrugs |
GB9802522D0 (en) | 1998-02-06 | 1998-04-01 | Montford University De | Hydroxylation activated prodrugs |
WO2001046110A2 (en) * | 1999-12-23 | 2001-06-28 | The University Of Georgia Research Foundation, Inc. | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states |
GB0007401D0 (en) * | 2000-03-27 | 2000-05-17 | Cancer Res Campaign Tech | Substituted chalcones as therapeeutic compounds |
-
2001
- 2001-10-03 GB GBGB0123780.9A patent/GB0123780D0/en not_active Ceased
-
2002
- 2002-09-30 US US10/491,614 patent/US7112698B2/en not_active Expired - Fee Related
- 2002-09-30 AT AT02762611T patent/ATE502911T1/de not_active IP Right Cessation
- 2002-09-30 ES ES02762611T patent/ES2364312T3/es not_active Expired - Lifetime
- 2002-09-30 DE DE60239548T patent/DE60239548D1/de not_active Expired - Lifetime
- 2002-09-30 CA CA2462228A patent/CA2462228C/en not_active Expired - Fee Related
- 2002-09-30 EP EP02762611A patent/EP1432669B1/de not_active Expired - Lifetime
- 2002-09-30 WO PCT/GB2002/004462 patent/WO2003029176A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
US7112698B2 (en) | 2006-09-26 |
ES2364312T3 (es) | 2011-08-31 |
WO2003029176A1 (en) | 2003-04-10 |
EP1432669A1 (de) | 2004-06-30 |
CA2462228C (en) | 2011-03-15 |
DE60239548D1 (de) | 2011-05-05 |
GB0123780D0 (en) | 2001-11-21 |
US20040259957A1 (en) | 2004-12-23 |
CA2462228A1 (en) | 2003-04-10 |
EP1432669B1 (de) | 2011-03-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |