ATE499114T1 - Stabilisierte wässrige erythropoietinhaltige arzneizusammensetzungen - Google Patents
Stabilisierte wässrige erythropoietinhaltige arzneizusammensetzungenInfo
- Publication number
- ATE499114T1 ATE499114T1 AT03764286T AT03764286T ATE499114T1 AT E499114 T1 ATE499114 T1 AT E499114T1 AT 03764286 T AT03764286 T AT 03764286T AT 03764286 T AT03764286 T AT 03764286T AT E499114 T1 ATE499114 T1 AT E499114T1
- Authority
- AT
- Austria
- Prior art keywords
- erythropoiety
- compositions containing
- medicinal compositions
- stabilized aqueous
- aqueous medicinal
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 1
- 102000003951 Erythropoietin Human genes 0.000 abstract 2
- 108090000394 Erythropoietin Proteins 0.000 abstract 2
- 229940105423 erythropoietin Drugs 0.000 abstract 2
- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical group [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229960000502 poloxamer Drugs 0.000 abstract 1
- 229920001983 poloxamer Polymers 0.000 abstract 1
- -1 poloxamer polyol Chemical class 0.000 abstract 1
- 229920005862 polyol Polymers 0.000 abstract 1
- 150000005846 sugar alcohols Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SI200200178A SI21258A (sl) | 2002-07-17 | 2002-07-17 | Stabilni farmacevtski pripravek, ki vsebuje eritropoietin in poloksamerni poliol |
| PCT/SI2003/000023 WO2004006958A1 (en) | 2002-07-17 | 2003-07-14 | Stable pharmaceutical composition comprising erythropoietin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE499114T1 true ATE499114T1 (de) | 2011-03-15 |
Family
ID=30113492
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03764286T ATE499114T1 (de) | 2002-07-17 | 2003-07-14 | Stabilisierte wässrige erythropoietinhaltige arzneizusammensetzungen |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7534870B2 (de) |
| EP (1) | EP1524998B1 (de) |
| JP (1) | JP2005535673A (de) |
| CN (1) | CN1668333A (de) |
| AT (1) | ATE499114T1 (de) |
| AU (1) | AU2003251284B2 (de) |
| CA (1) | CA2492485A1 (de) |
| DE (1) | DE60336142D1 (de) |
| MX (1) | MXPA05000662A (de) |
| SI (1) | SI21258A (de) |
| WO (1) | WO2004006958A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE553747T1 (de) * | 2003-06-10 | 2012-05-15 | Lg Life Sciences Ltd | Stabile wässrige lösung von human-erythropoietin, die kein serumalbumin enthält |
| CN100342909C (zh) * | 2005-05-11 | 2007-10-17 | 北京双鹭药业股份有限公司 | 一种胸腺素α1的水溶液制剂、其制备方法及应用 |
| EP1997505A4 (de) * | 2006-03-22 | 2013-02-13 | Chugai Pharmaceutical Co Ltd | Zubereitung einer erythropoetinlösung |
| JP2011116752A (ja) * | 2009-10-29 | 2011-06-16 | Jcr Pharmaceuticals Co Ltd | エリスロポエチン含有水性液剤 |
| US8829163B2 (en) * | 2010-01-19 | 2014-09-09 | Hanmi Science Co., Ltd | Liquid formulations for long-acting erythropoietin conjugate |
| US20150377869A1 (en) * | 2014-06-25 | 2015-12-31 | Bio-Rad Laboratories, Inc. | Purification of nanoparticle-antibody conjugates |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6191131A (ja) | 1984-10-09 | 1986-05-09 | Chugai Pharmaceut Co Ltd | 医薬品の吸着防止方法および組成物 |
| GB8822857D0 (en) | 1988-09-29 | 1988-11-02 | Patralan Ltd | Pharmaceutical formulations |
| US5968899A (en) * | 1994-06-03 | 1999-10-19 | Tsumura & Co. | Medicinal compositions of peptides with EACA or tranexamic acid for enhanced mucosal absorption |
| US6284234B1 (en) * | 1998-08-04 | 2001-09-04 | Johnson & Johnson Consumer Companies, Inc. | Topical delivery systems for active agents |
| AU2001236005A1 (en) * | 2000-02-29 | 2001-09-12 | Chugai Seiyaku Kabushiki Kaisha | Preparations stabilized over long time |
| JP3967594B2 (ja) * | 2000-05-15 | 2007-08-29 | エフ．ホフマン−ラ ロシュ アーゲー | 新しい薬剤組成物 |
| AU2001273041A1 (en) * | 2000-06-26 | 2002-01-08 | Board Of Regents Of The University Of Nebraska | Methods for use of delivery composition for expanding, activating, committing ormobilizing one or more pluripotent, self-renewing and committed stem cells |
-
2002
- 2002-07-17 SI SI200200178A patent/SI21258A/sl not_active IP Right Cessation
-
2003
- 2003-07-14 JP JP2004521371A patent/JP2005535673A/ja active Pending
- 2003-07-14 US US10/521,298 patent/US7534870B2/en not_active Expired - Fee Related
- 2003-07-14 DE DE60336142T patent/DE60336142D1/de not_active Expired - Lifetime
- 2003-07-14 EP EP03764286A patent/EP1524998B1/de not_active Expired - Lifetime
- 2003-07-14 CA CA002492485A patent/CA2492485A1/en not_active Abandoned
- 2003-07-14 CN CNA038170078A patent/CN1668333A/zh active Pending
- 2003-07-14 AT AT03764286T patent/ATE499114T1/de not_active IP Right Cessation
- 2003-07-14 AU AU2003251284A patent/AU2003251284B2/en not_active Ceased
- 2003-07-14 WO PCT/SI2003/000023 patent/WO2004006958A1/en not_active Ceased
- 2003-07-14 MX MXPA05000662A patent/MXPA05000662A/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003251284B9 (en) | 2004-02-02 |
| US7534870B2 (en) | 2009-05-19 |
| EP1524998B1 (de) | 2011-02-23 |
| SI21258A (sl) | 2004-02-29 |
| EP1524998A1 (de) | 2005-04-27 |
| CN1668333A (zh) | 2005-09-14 |
| CA2492485A1 (en) | 2004-01-22 |
| JP2005535673A (ja) | 2005-11-24 |
| MXPA05000662A (es) | 2005-08-19 |
| AU2003251284A1 (en) | 2004-02-02 |
| AU2003251284B2 (en) | 2007-08-02 |
| WO2004006958A1 (en) | 2004-01-22 |
| US20050202091A1 (en) | 2005-09-15 |
| WO2004006958A8 (en) | 2005-01-13 |
| DE60336142D1 (de) | 2011-04-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |