ATE493652T1 - Quantitative assays für pdgfr-beta- in körperflüssigkeiten - Google Patents
Quantitative assays für pdgfr-beta- in körperflüssigkeitenInfo
- Publication number
- ATE493652T1 ATE493652T1 AT06801170T AT06801170T ATE493652T1 AT E493652 T1 ATE493652 T1 AT E493652T1 AT 06801170 T AT06801170 T AT 06801170T AT 06801170 T AT06801170 T AT 06801170T AT E493652 T1 ATE493652 T1 AT E493652T1
- Authority
- AT
- Austria
- Prior art keywords
- beta
- diseases
- body fluid
- patient
- monitor
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57415—Specifically defined cancers of breast
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57419—Specifically defined cancers of colon
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57434—Specifically defined cancers of prostate
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57449—Specifically defined cancers of ovaries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/475—Assays involving growth factors
- G01N2333/49—Platelet-derived growth factor [PDGF]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70780605P | 2005-08-11 | 2005-08-11 | |
PCT/US2006/031245 WO2007021860A2 (en) | 2005-08-11 | 2006-08-10 | QUANTITATIVE ASSAYS FOR PDGFR-β IN BODY FLUIDS |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE493652T1 true ATE493652T1 (de) | 2011-01-15 |
Family
ID=37758168
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06801170T ATE493652T1 (de) | 2005-08-11 | 2006-08-10 | Quantitative assays für pdgfr-beta- in körperflüssigkeiten |
Country Status (5)
Country | Link |
---|---|
US (1) | US20070037224A1 (de) |
EP (1) | EP1913391B1 (de) |
AT (1) | ATE493652T1 (de) |
DE (1) | DE602006019262D1 (de) |
WO (1) | WO2007021860A2 (de) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8124630B2 (en) | 1999-01-13 | 2012-02-28 | Bayer Healthcare Llc | ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
CA2359244C (en) * | 1999-01-13 | 2013-10-08 | Bayer Corporation | .omega.-carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors |
US7371763B2 (en) * | 2001-04-20 | 2008-05-13 | Bayer Pharmaceuticals Corporation | Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas |
US20080108672A1 (en) * | 2002-01-11 | 2008-05-08 | Bernd Riedl | Omega-Carboxyaryl Substituted Diphenyl Ureas As Raf Kinase Inhibitors |
DK1478358T3 (da) | 2002-02-11 | 2013-10-07 | Bayer Healthcare Llc | Sorafenibtosylat til behandling af sygdomme kendetegnet ved unormal angiogenese |
NZ626589A (en) * | 2003-02-21 | 2016-01-29 | Resmed Ltd | Nasal assembly |
UY28213A1 (es) * | 2003-02-28 | 2004-09-30 | Bayer Pharmaceuticals Corp | Nuevos derivados de cianopiridina útiles en el tratamiento de cáncer y otros trastornos. |
US7191068B2 (en) * | 2003-03-25 | 2007-03-13 | Proteogenix, Inc. | Proteomic analysis of biological fluids |
US8068990B2 (en) * | 2003-03-25 | 2011-11-29 | Hologic, Inc. | Diagnosis of intra-uterine infection by proteomic analysis of cervical-vaginal fluids |
PT1626714E (pt) * | 2003-05-20 | 2007-08-24 | Bayer Pharmaceuticals Corp | Diarilureias para doenças mediadas por pdgfr |
JP2009512860A (ja) * | 2005-10-21 | 2009-03-26 | バイエル ヘルスケア エルエルシー | がんの予測及び予後の検査方法、並びにがん治療のモニタリング |
US8026083B2 (en) * | 2007-04-03 | 2011-09-27 | Oxyrane Uk Limited | Yarrowia lipolytica and Pichia pastoris HAC1 nucleic acids |
US20110124965A1 (en) * | 2008-05-08 | 2011-05-26 | Park Jason Y | Chemiluminescence enhanced detection |
US8741287B2 (en) * | 2008-06-18 | 2014-06-03 | Abbott Laboratories | PlGF-1 assay and kits and components thereof |
JP2011525241A (ja) * | 2008-06-18 | 2011-09-15 | アボット・ラボラトリーズ | PlGF−1コンパニオン診断方法および製品 |
US20100004306A1 (en) * | 2008-06-18 | 2010-01-07 | Abbott Laboratories | PIGF-1 Assay and kits and components thereof |
EP2324111B1 (de) * | 2008-09-10 | 2013-07-03 | Life & Brain GmbH | Peripherbereichs-tumorzellen sowie verfahren zu ihrer herstellung und verwendung |
WO2010106140A1 (en) * | 2009-03-19 | 2010-09-23 | Universite D'angers | Non-invasive method for assessing liver fibrosis progression |
CN102445543B (zh) * | 2010-10-08 | 2014-03-12 | 中国医学科学院肿瘤研究所 | 辅助诊断肺癌淋巴结转移的试剂 |
GB201204014D0 (en) * | 2012-03-07 | 2012-04-18 | Univ Leeds | Diagnostic marker compounds and their use |
WO2014145181A1 (en) | 2013-03-15 | 2014-09-18 | Morphotek, Inc. | Methods for determining prognosis of colorectal cancer |
JP6489658B2 (ja) * | 2013-04-25 | 2019-03-27 | シービーエス バイオサイエンス,カンパニー,リミテッド | 肝細胞癌において分子標的治療の感受性を増加させるための分析方法 |
EP3491388B1 (de) | 2016-08-01 | 2021-09-01 | Centre Hospitalier Universitaire d'Angers | Multi-zielgerichteten fibrosetests |
WO2020099487A1 (en) * | 2018-11-14 | 2020-05-22 | Vrije Universiteit Brussel | Soluble pdgfrbeta as a biomarker for fibrosis |
KR102363980B1 (ko) * | 2020-04-13 | 2022-02-15 | 전남대학교산학협력단 | 전이성 뇌종양의 진단 또는 예후 분석용 바이오마커 및 이를 이용한 진단방법 |
JP2024511358A (ja) * | 2021-03-19 | 2024-03-13 | イーライ リリー アンド カンパニー | PDGFRα阻害剤でがんを治療する方法 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US4745181A (en) | 1986-10-06 | 1988-05-17 | Ciba Corning Diagnostics Corp. | Polysubstituted aryl acridinium esters |
US6110737A (en) * | 1988-02-02 | 2000-08-29 | The Regents Of The University Of California | Human platelet-derived growth factor receptor, type A |
US6372438B1 (en) * | 1988-02-02 | 2002-04-16 | The Regents Of The University Of California | Human platelet-derived growth factor receptors |
EP0869177B1 (de) * | 1989-02-09 | 2008-06-04 | THE UNITED STATES OF AMERICA, as represented by the Secretary of the Department of Health and Human Services | Polyklonale antikörper gegen den menschlichen alpha-pdgf-rezeptor und dessen verwendung |
US6228600B1 (en) * | 1992-07-20 | 2001-05-08 | The United States Of America As Represented By The Department Of Health And Human Services | Immunoassays for the alpha platelet-derived growth factor receptor |
US5468468A (en) * | 1989-02-09 | 1995-11-21 | The United States Of America, As Represented By The Secretary Of The Department Of Health & Human Services | Method for making a monoclonal antibody, monoclonal antibodies to α PD |
WO1990014425A1 (en) * | 1989-05-22 | 1990-11-29 | Zymogenetics, Inc. | PDGF α-RECEPTOR |
DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
EP0617706B1 (de) | 1991-11-25 | 2001-10-17 | Enzon, Inc. | Multivalente antigen-bindende proteine |
US5817310A (en) * | 1991-12-02 | 1998-10-06 | Cor Therapeutics, Inc. | Inhibitory immunoglobulin polypeptides to human PDGF beta receptor |
US5395752A (en) | 1993-03-19 | 1995-03-07 | Ciba Corning Diagnostics Corp. | Long emission wavelength chemiluminescent compounds and their use in test assays |
US6264949B1 (en) * | 1998-09-29 | 2001-07-24 | Mount Sinai School Of Medicine Of New York University | Noninvasive agents for diagnosis and prognosis of the progression of fibrosis |
EP1573316B1 (de) * | 2002-03-01 | 2009-08-26 | Siemens Healthcare Diagnostics Inc. | Assays zur überwachung von krebspatienten auf grundlage der spiegel des analyten für die extrazelluläre domäne (ecd) des epidermalen wachstumsfaktor-rezeptors (egfr), allein oder in kombination mit anderen analyten, in proben von körperflüssigkeiten |
PT1626714E (pt) * | 2003-05-20 | 2007-08-24 | Bayer Pharmaceuticals Corp | Diarilureias para doenças mediadas por pdgfr |
WO2005015236A2 (en) * | 2003-07-18 | 2005-02-17 | Roche Diagnostics Gmbh | A method for predicting the progression of adenocarcinoma |
-
2006
- 2006-08-10 US US11/502,013 patent/US20070037224A1/en not_active Abandoned
- 2006-08-10 WO PCT/US2006/031245 patent/WO2007021860A2/en active Application Filing
- 2006-08-10 DE DE602006019262T patent/DE602006019262D1/de active Active
- 2006-08-10 AT AT06801170T patent/ATE493652T1/de not_active IP Right Cessation
- 2006-08-10 EP EP06801170A patent/EP1913391B1/de not_active Not-in-force
Also Published As
Publication number | Publication date |
---|---|
EP1913391A4 (de) | 2009-02-18 |
WO2007021860A2 (en) | 2007-02-22 |
EP1913391A2 (de) | 2008-04-23 |
US20070037224A1 (en) | 2007-02-15 |
WO2007021860A3 (en) | 2007-10-04 |
EP1913391B1 (de) | 2010-12-29 |
WO2007021860B1 (en) | 2008-02-28 |
DE602006019262D1 (de) | 2011-02-10 |
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Legal Events
Date | Code | Title | Description |
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |