ATE488497T1 - Pyrrolidinderivate, die als antagonisten des ccr3-rezeptors wirken - Google Patents
Pyrrolidinderivate, die als antagonisten des ccr3-rezeptors wirkenInfo
- Publication number
- ATE488497T1 ATE488497T1 AT05701246T AT05701246T ATE488497T1 AT E488497 T1 ATE488497 T1 AT E488497T1 AT 05701246 T AT05701246 T AT 05701246T AT 05701246 T AT05701246 T AT 05701246T AT E488497 T1 ATE488497 T1 AT E488497T1
- Authority
- AT
- Austria
- Prior art keywords
- antagonists
- action
- pyrrolidine derivatives
- ccr3 receptor
- compounds
- Prior art date
Links
- 102000004499 CCR3 Receptors Human genes 0.000 title 1
- 108010017316 CCR3 Receptors Proteins 0.000 title 1
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical class C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 102100024167 C-C chemokine receptor type 3 Human genes 0.000 abstract 1
- 101710149862 C-C chemokine receptor type 3 Proteins 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
- Holo Graphy (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0402101.0A GB0402101D0 (en) | 2004-01-30 | 2004-01-30 | Organic compounds |
| PCT/EP2005/000874 WO2005075420A2 (en) | 2004-01-30 | 2005-01-28 | Pyrrolidine derivatives acting as ccr3-receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE488497T1 true ATE488497T1 (de) | 2010-12-15 |
Family
ID=31971770
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05701246T ATE488497T1 (de) | 2004-01-30 | 2005-01-28 | Pyrrolidinderivate, die als antagonisten des ccr3-rezeptors wirken |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US7754758B2 (de) |
| EP (1) | EP1791815B1 (de) |
| JP (1) | JP2007519680A (de) |
| KR (1) | KR20060128971A (de) |
| CN (1) | CN1910145B (de) |
| AT (1) | ATE488497T1 (de) |
| AU (1) | AU2005211491B2 (de) |
| BR (1) | BRPI0507283A (de) |
| CA (1) | CA2552928A1 (de) |
| DE (1) | DE602005024828D1 (de) |
| GB (1) | GB0402101D0 (de) |
| MX (1) | MXPA06008572A (de) |
| RU (1) | RU2006131044A (de) |
| WO (1) | WO2005075420A2 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3452029A4 (de) * | 2016-05-04 | 2019-10-30 | Bristol-Myers Squibb Company | Inhibitoren der indoleamin-2,3-dioxygenase und verfahren zu deren verwendung |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5274097A (en) * | 1988-04-19 | 1993-12-28 | Bayer Aktiengesellschaft | 1,3-disubstituted pyrrolidines |
| DE3835291A1 (de) * | 1988-04-19 | 1989-11-02 | Bayer Ag | 1,3-disubstituierte pyrrolidine |
| US6605623B1 (en) * | 1998-12-18 | 2003-08-12 | Bristol-Myers Squibb Pharma Co. | N-ureidoalkyl-piperidines as modulators of chemokine receptor activity |
| CO5300399A1 (es) * | 2000-02-25 | 2003-07-31 | Astrazeneca Ab | Heterocicliocs que contienen nitrogeno, proceso para su preparacion y composiciones farmaceuticas que los contienen |
| AR028947A1 (es) * | 2000-06-20 | 2003-05-28 | Astrazeneca Ab | Compuestos novedosos |
| EP1363881A2 (de) * | 2000-06-21 | 2003-11-26 | Bristol-Myers Squibb Pharma Company | N-ureidoalkyl-piperidine zur verwendung als chemokin-receptor-modulatoren |
| TW200305395A (en) * | 2002-03-15 | 2003-11-01 | Novartis Ag | Organic compounds |
-
2004
- 2004-01-30 GB GBGB0402101.0A patent/GB0402101D0/en not_active Ceased
-
2005
- 2005-01-28 WO PCT/EP2005/000874 patent/WO2005075420A2/en not_active Ceased
- 2005-01-28 US US10/585,615 patent/US7754758B2/en not_active Expired - Fee Related
- 2005-01-28 KR KR1020067015275A patent/KR20060128971A/ko not_active Withdrawn
- 2005-01-28 AU AU2005211491A patent/AU2005211491B2/en not_active Ceased
- 2005-01-28 CN CN2005800026053A patent/CN1910145B/zh not_active Expired - Fee Related
- 2005-01-28 RU RU2006131044/04A patent/RU2006131044A/ru not_active Application Discontinuation
- 2005-01-28 AT AT05701246T patent/ATE488497T1/de not_active IP Right Cessation
- 2005-01-28 DE DE602005024828T patent/DE602005024828D1/de not_active Expired - Lifetime
- 2005-01-28 MX MXPA06008572A patent/MXPA06008572A/es not_active Application Discontinuation
- 2005-01-28 JP JP2006550121A patent/JP2007519680A/ja active Pending
- 2005-01-28 CA CA002552928A patent/CA2552928A1/en not_active Abandoned
- 2005-01-28 EP EP05701246A patent/EP1791815B1/de not_active Expired - Lifetime
- 2005-01-28 BR BRPI0507283-2A patent/BRPI0507283A/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE602005024828D1 (de) | 2010-12-30 |
| JP2007519680A (ja) | 2007-07-19 |
| GB0402101D0 (en) | 2004-03-03 |
| AU2005211491B2 (en) | 2008-09-11 |
| RU2006131044A (ru) | 2008-03-10 |
| KR20060128971A (ko) | 2006-12-14 |
| CN1910145B (zh) | 2010-06-16 |
| MXPA06008572A (es) | 2006-08-28 |
| CA2552928A1 (en) | 2005-08-18 |
| BRPI0507283A (pt) | 2007-07-03 |
| WO2005075420A2 (en) | 2005-08-18 |
| EP1791815A2 (de) | 2007-06-06 |
| AU2005211491A1 (en) | 2005-08-18 |
| CN1910145A (zh) | 2007-02-07 |
| EP1791815B1 (de) | 2010-11-17 |
| US20090306138A1 (en) | 2009-12-10 |
| US7754758B2 (en) | 2010-07-13 |
| WO2005075420A3 (en) | 2005-10-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |