ATE486602T1 - Pyrrolo (3, 2, 1-ij) chinolin-4-on-derivate zur behandlung von tuberkulose - Google Patents

Pyrrolo (3, 2, 1-ij) chinolin-4-on-derivate zur behandlung von tuberkulose

Info

Publication number
ATE486602T1
ATE486602T1 AT08736082T AT08736082T ATE486602T1 AT E486602 T1 ATE486602 T1 AT E486602T1 AT 08736082 T AT08736082 T AT 08736082T AT 08736082 T AT08736082 T AT 08736082T AT E486602 T1 ATE486602 T1 AT E486602T1
Authority
AT
Austria
Prior art keywords
tuberculosis
treatment
derivatives
quinolin
pyrrolo
Prior art date
Application number
AT08736082T
Other languages
English (en)
Inventor
Lluis Ballell-Pages
David Barros-Aguirre
Julia Castro-Pichel
Modesto Jesus Remuinan-Blanco
Jose Maria Fiandor-Roman
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE486602T1 publication Critical patent/ATE486602T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT08736082T 2007-04-13 2008-04-10 Pyrrolo (3, 2, 1-ij) chinolin-4-on-derivate zur behandlung von tuberkulose ATE486602T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07381033A EP1980251A1 (de) 2007-04-13 2007-04-13 Pyrrolo[3,2,1-ij]quinolin-4-on Derivate zur Behandlung der Tuberkulose
PCT/EP2008/054363 WO2008125594A1 (en) 2007-04-13 2008-04-10 Pyrrolo (3, 2, 1-ij) quinoline-4-one derivatives for treating tuberculosis

Publications (1)

Publication Number Publication Date
ATE486602T1 true ATE486602T1 (de) 2010-11-15

Family

ID=38456499

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08736082T ATE486602T1 (de) 2007-04-13 2008-04-10 Pyrrolo (3, 2, 1-ij) chinolin-4-on-derivate zur behandlung von tuberkulose

Country Status (8)

Country Link
US (1) US20100048544A1 (de)
EP (2) EP1980251A1 (de)
JP (1) JP2010523622A (de)
CN (1) CN101678015A (de)
AT (1) ATE486602T1 (de)
DE (1) DE602008003322D1 (de)
ES (1) ES2353631T3 (de)
WO (1) WO2008125594A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1954697T1 (sl) * 2005-10-21 2010-05-31 Glaxo Group Ltd Peri kondenzirane triciklične spojine uporabne kot antibakterijska sredstva
GB0608263D0 (en) 2006-04-26 2006-06-07 Glaxo Group Ltd Compounds
NZ579877A (en) * 2007-04-20 2011-09-30 Glaxo Group Ltd Tricyclic nitrogen containing compounds as antibacterial agents
ES2411930T3 (es) 2008-02-20 2013-07-09 Actelion Pharmaceuticals Ltd. Compuestos antibióticos azatricíclicos
KR101294962B1 (ko) 2008-10-07 2013-08-12 액테리온 파마슈티칼 리미티드 트리사이클 옥사졸리디논 항생제 화합물
US8377962B2 (en) 2009-04-08 2013-02-19 Idenix Pharmaceuticals, Inc. Macrocyclic serine protease inhibitors
US9284307B2 (en) 2009-08-05 2016-03-15 Idenix Pharmaceuticals Llc Macrocyclic serine protease inhibitors
CN110483499A (zh) 2009-11-05 2019-11-22 圣母大学 咪唑并[1,2-a]吡啶类化合物及其合成及使用方法
US9353100B2 (en) 2011-02-10 2016-05-31 Idenix Pharmaceuticals Llc Macrocyclic serine protease inhibitors, pharmaceutical compositions thereof, and their use for treating HCV infections
WO2013038374A1 (en) 2011-09-16 2013-03-21 Actelion Pharmaceuticals Ltd Process for manufacturing a synthetic intermediate
EP2785721A1 (de) 2011-11-30 2014-10-08 Actelion Pharmaceuticals Ltd. 3,7-disubstituierte octahydro-2h-pyrido [4,3-e] [1,3] oxazin-2-on-antibiotika
EP3101012A1 (de) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft Neue gadoliniumchelat-verbindung zur verwendung in der magnetresonanzbildgebung
US10919888B2 (en) 2015-09-17 2021-02-16 University Of Notre Dame Du Lac Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection
EP3544964B1 (de) 2016-11-28 2020-06-17 Bayer Pharma Aktiengesellschaft Gadolinium-chelat-verbindung mit hoher relaxivität zur verwendung in der magnetresonanzbildgebung
IL321215B2 (en) 2018-11-23 2026-05-01 Bayer Ag Contrast media formulation and process for its preparation

Also Published As

Publication number Publication date
WO2008125594A1 (en) 2008-10-23
EP1980251A1 (de) 2008-10-15
EP2136807B1 (de) 2010-11-03
DE602008003322D1 (de) 2010-12-16
CN101678015A (zh) 2010-03-24
ES2353631T3 (es) 2011-03-03
US20100048544A1 (en) 2010-02-25
JP2010523622A (ja) 2010-07-15
EP2136807A1 (de) 2009-12-30

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