ATE478963T1 - Gene als diagnostische werkzeuge für autismus - Google Patents

Gene als diagnostische werkzeuge für autismus

Info

Publication number
ATE478963T1
ATE478963T1 AT04777436T AT04777436T ATE478963T1 AT E478963 T1 ATE478963 T1 AT E478963T1 AT 04777436 T AT04777436 T AT 04777436T AT 04777436 T AT04777436 T AT 04777436T AT E478963 T1 ATE478963 T1 AT E478963T1
Authority
AT
Austria
Prior art keywords
autism
tdt
allele
observed
genes
Prior art date
Application number
AT04777436T
Other languages
English (en)
Inventor
James Millonig
Linda Brzustowicz
Neda Gharani
Original Assignee
Univ New Jersey Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New Jersey Med filed Critical Univ New Jersey Med
Application granted granted Critical
Publication of ATE478963T1 publication Critical patent/ATE478963T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
AT04777436T 2003-07-03 2004-07-01 Gene als diagnostische werkzeuge für autismus ATE478963T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48463303P 2003-07-03 2003-07-03
PCT/US2004/021301 WO2005007812A2 (en) 2003-07-03 2004-07-01 Genes as diagnostic tools for autism

Publications (1)

Publication Number Publication Date
ATE478963T1 true ATE478963T1 (de) 2010-09-15

Family

ID=34079057

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04777436T ATE478963T1 (de) 2003-07-03 2004-07-01 Gene als diagnostische werkzeuge für autismus

Country Status (5)

Country Link
EP (1) EP1649061B1 (de)
AT (1) ATE478963T1 (de)
DE (1) DE602004028837D1 (de)
ES (1) ES2354238T3 (de)
WO (1) WO2005007812A2 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2897780B1 (fr) * 2006-02-28 2008-05-23 Centre Nat Rech Scient Utilisation de la proteine a homeodomaine engrailed comme anxiolytique
US8709762B2 (en) 2010-03-02 2014-04-29 Bio-Rad Laboratories, Inc. System for hot-start amplification via a multiple emulsion
US11130128B2 (en) 2008-09-23 2021-09-28 Bio-Rad Laboratories, Inc. Detection method for a target nucleic acid
US9132394B2 (en) 2008-09-23 2015-09-15 Bio-Rad Laboratories, Inc. System for detection of spaced droplets
US9156010B2 (en) 2008-09-23 2015-10-13 Bio-Rad Laboratories, Inc. Droplet-based assay system
US9399215B2 (en) 2012-04-13 2016-07-26 Bio-Rad Laboratories, Inc. Sample holder with a well having a wicking promoter
WO2011120020A1 (en) 2010-03-25 2011-09-29 Quantalife, Inc. Droplet transport system for detection
US12090480B2 (en) 2008-09-23 2024-09-17 Bio-Rad Laboratories, Inc. Partition-based method of analysis
US9194861B2 (en) 2009-09-02 2015-11-24 Bio-Rad Laboratories, Inc. Method of mixing fluids by coalescence of multiple emulsions
US10512910B2 (en) 2008-09-23 2019-12-24 Bio-Rad Laboratories, Inc. Droplet-based analysis method
US8633015B2 (en) 2008-09-23 2014-01-21 Bio-Rad Laboratories, Inc. Flow-based thermocycling system with thermoelectric cooler
US9492797B2 (en) 2008-09-23 2016-11-15 Bio-Rad Laboratories, Inc. System for detection of spaced droplets
US9598725B2 (en) 2010-03-02 2017-03-21 Bio-Rad Laboratories, Inc. Emulsion chemistry for encapsulated droplets
US12162008B2 (en) 2008-09-23 2024-12-10 Bio-Rad Laboratories, Inc. Partition-based method of analysis
US8951939B2 (en) 2011-07-12 2015-02-10 Bio-Rad Laboratories, Inc. Digital assays with multiplexed detection of two or more targets in the same optical channel
US9764322B2 (en) 2008-09-23 2017-09-19 Bio-Rad Laboratories, Inc. System for generating droplets with pressure monitoring
CN102405402A (zh) 2008-09-23 2012-04-04 阔达生命有限公司 基于液滴的测定系统
US9417190B2 (en) 2008-09-23 2016-08-16 Bio-Rad Laboratories, Inc. Calibrations and controls for droplet-based assays
CN101684496A (zh) * 2008-09-27 2010-03-31 上海裕隆生物科技有限公司 一种儿童自闭症易感基因检测试剂盒
JP5881420B2 (ja) * 2008-11-12 2016-03-09 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション 自閉症関連遺伝子マーカー
WO2011067296A1 (en) 2009-12-01 2011-06-09 Integragen A combination of eight risk alleles associated with autism
CA2767113A1 (en) 2010-03-25 2011-09-29 Bio-Rad Laboratories, Inc. Detection system for droplet-based assays
EP2550528B1 (de) 2010-03-25 2019-09-11 Bio-Rad Laboratories, Inc. Tropfenerzeugung für tropfenbasierte prüfungen
US20130137585A1 (en) 2010-05-04 2013-05-30 Jerome Carayol New combination of eight risk alleles associated with autism
CA2816712C (en) 2010-11-01 2018-12-11 Donald A. Masquelier System for forming emulsions
US12097495B2 (en) 2011-02-18 2024-09-24 Bio-Rad Laboratories, Inc. Methods and compositions for detecting genetic material
JP2014509865A (ja) 2011-03-18 2014-04-24 バイオ−ラッド・ラボラトリーズ・インコーポレーテッド シグナルの組合せ使用による多重化デジタルアッセイ
EP2702175B1 (de) 2011-04-25 2018-08-08 Bio-Rad Laboratories, Inc. Verfahren und zusammensetzungen zur nukleinsäureanalyse
WO2013019751A1 (en) 2011-07-29 2013-02-07 Bio-Rad Laboratories, Inc., Library characterization by digital assay
US20180245037A1 (en) * 2015-09-11 2018-08-30 INSERM (Institut National de la Sante et de la Researche Medicale) Non-Invasive Methods for Assessing Genetic Integrity of Pluripotent Stem Cells

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4650764A (en) 1983-04-12 1987-03-17 Wisconsin Alumni Research Foundation Helper cell
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
NL8720442A (nl) 1986-08-18 1989-04-03 Clinical Technologies Ass Afgeefsystemen voor farmacologische agentia.
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US4980289A (en) 1987-04-27 1990-12-25 Wisconsin Alumni Research Foundation Promoter deficient retroviral vector
AU612370B2 (en) 1987-05-21 1991-07-11 Micromet Ag Targeted multifunctional proteins
US5132405A (en) 1987-05-21 1992-07-21 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
US5124263A (en) 1989-01-12 1992-06-23 Wisconsin Alumni Research Foundation Recombination resistant retroviral helper cell and products produced thereby
US5354844A (en) 1989-03-16 1994-10-11 Boehringer Ingelheim International Gmbh Protein-polycation conjugates
US5399346A (en) 1989-06-14 1995-03-21 The United States Of America As Represented By The Department Of Health And Human Services Gene therapy
US5013556A (en) 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
US5906928A (en) 1993-07-30 1999-05-25 University Of Medicine And Dentistry Of New Jersey Efficient gene transfer into primary murine lymphocytes obviating the need for drug selection
CA2187818A1 (en) 1994-04-15 1995-10-26 Robert W. Overell Gene delivery fusion proteins
US9002545B2 (en) 2011-01-07 2015-04-07 Wabtec Holding Corp. Data improvement system and method

Also Published As

Publication number Publication date
EP1649061B1 (de) 2010-08-25
DE602004028837D1 (de) 2010-10-07
EP1649061A2 (de) 2006-04-26
EP1649061A4 (de) 2007-07-18
WO2005007812A2 (en) 2005-01-27
WO2005007812A3 (en) 2005-06-09
ES2354238T3 (es) 2011-03-11

Similar Documents

Publication Publication Date Title
ATE478963T1 (de) Gene als diagnostische werkzeuge für autismus
Mill et al. Expression of the dopamine transporter gene is regulated by the 3′ UTR VNTR: Evidence from brain and lymphocytes using quantitative RT‐PCR
Gayan et al. Bivariate linkage scan for reading disability and attention‐deficit/hyperactivity disorder localizes pleiotropic loci
Joshi et al. DNA methylation profiling of uniparental disomy subjects provides a map of parental epigenetic bias in the human genome
Brkanac et al. Evaluation of candidate genes for DYX1 and DYX2 in families with dyslexia
Haberstick et al. Population frequencies of the triallelic 5HTTLPR in six ethnicially diverse samples from North America, Southeast Asia, and Africa
US9574227B2 (en) Method for detecting variation of gene for non-diagnostic purpose based on fluorescence quenching and probe thereof
Scerri et al. Identification of candidate genes for dyslexia susceptibility on chromosome 18
Ai et al. DNA methylation as a biomarker for neuropsychiatric diseases
Muir et al. Markers close to the dopamine D5 receptor gene (DRD5) show significant association with schizophrenia but not bipolar disorder
Lessig et al. Y-SNP-genotyping–a new approach in forensic analysis
Kebir et al. Family-based association study of common variants, rare mutation study and epistatic interaction detection in HDAC genes in schizophrenia
McIver et al. Population-scale analysis of human microsatellites reveals novel sources of exonic variation
Jian et al. A novel SNP-STR system based on a capillary electrophoresis platform
Kim et al. Family-based association study of DAT1 and DRD4 polymorphism in Korean children with ADHD
Wigg et al. Association of ADHD and the Protogenin gene in the chromosome 15q21. 3 reading disabilities linkage region
Mouri et al. TPH2 is not a susceptibility gene for suicide in Japanese population
CN103502469B (zh) 强直性脊柱炎易感性单核苷酸多态性的检测方法、试剂盒及其应用
AU2011249763A1 (en) A new combination of eight risk alleles associated with autism
WO2011076783A2 (en) A method for evaluating a risk for a transmissible neuropsychiatric disorder
JPWO2016132736A1 (ja) イリノテカンによる副作用の発生リスクの予測を補助する方法
Voskarides et al. Screening for mutations in kidney-related genes using SURVEYOR nuclease for cleavage at heteroduplex mismatches
Becker et al. New alleles and mutational events at 14 STR loci from different German populations
Watanabe et al. Rare truncating variations and risk of schizophrenia: whole-exome sequencing in three families with affected siblings and a three-stage follow-up study in a Japanese population
CN106480220B (zh) 可视化mthfr等位基因分型检测试剂盒

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1649061

Country of ref document: EP