ATE477236T1 - Alpha-aminosäurederivate mit entzündungshemmender wirkung - Google Patents
Alpha-aminosäurederivate mit entzündungshemmender wirkungInfo
- Publication number
- ATE477236T1 ATE477236T1 AT05752620T AT05752620T ATE477236T1 AT E477236 T1 ATE477236 T1 AT E477236T1 AT 05752620 T AT05752620 T AT 05752620T AT 05752620 T AT05752620 T AT 05752620T AT E477236 T1 ATE477236 T1 AT E477236T1
- Authority
- AT
- Austria
- Prior art keywords
- alpha
- amino acid
- acid derivatives
- inflammatory effect
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/10—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to carbon atoms of six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/08—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Transplantation (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT001347A ITMI20041347A1 (it) | 2004-07-05 | 2004-07-05 | Derivati di alfa-amminoacidi ad attivita'antiinfiammatoria |
| PCT/EP2005/052597 WO2006003068A2 (en) | 2004-07-05 | 2005-06-07 | Alpha-amino acid derivatives with antiinflammatory activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE477236T1 true ATE477236T1 (de) | 2010-08-15 |
Family
ID=35783213
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05752620T ATE477236T1 (de) | 2004-07-05 | 2005-06-07 | Alpha-aminosäurederivate mit entzündungshemmender wirkung |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7635788B2 (de) |
| EP (1) | EP1763507B1 (de) |
| JP (1) | JP4769248B2 (de) |
| KR (1) | KR101183154B1 (de) |
| CN (1) | CN100540530C (de) |
| AT (1) | ATE477236T1 (de) |
| BR (1) | BRPI0512751A (de) |
| CA (1) | CA2570307C (de) |
| DE (1) | DE602005022868D1 (de) |
| ES (1) | ES2350585T3 (de) |
| IT (1) | ITMI20041347A1 (de) |
| WO (1) | WO2006003068A2 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1396915B1 (it) * | 2009-10-23 | 2012-12-20 | Italfarmaco Spa | Dietil-[6-(4-idrossicarbamoil-fenil-carbamoilossimetil)-naftalen-2-il-metil]-ammonio cloruro ed altri derivati della n-idrossi-benzammide per l'uso nel trattamento di infezioni da hiv. |
| US8217079B2 (en) | 2010-03-26 | 2012-07-10 | Italfarmaco Spa | Method for treating Philadelphia-negative myeloproliferative syndromes |
| CN102898332B (zh) * | 2011-07-25 | 2015-05-06 | 中国医学科学院医药生物技术研究所 | 一种异羟肟酸类衍生物、其药物组合物、制备方法及用途 |
| ITUB20155193A1 (it) | 2015-11-03 | 2017-05-03 | Italfarmaco Spa | Sospensioni orali di Givinostat fisicamente e chimicamente stabili |
| IT201600074606A1 (it) * | 2016-07-18 | 2018-01-18 | Italfarmaco Spa | New benzo-N-hydroxy amide compounds having antitumor activity |
| WO2018054960A1 (en) | 2016-09-21 | 2018-03-29 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for predicting and treating resistance to chemotherapy in npm-alk(+) alcl |
| CN111989325A (zh) | 2018-04-18 | 2020-11-24 | 星座制药公司 | 甲基修饰酶的调节剂、其组合物和用途 |
| WO2019226491A1 (en) | 2018-05-21 | 2019-11-28 | Constellation Pharmaceuticals, Inc. | Modulators of methyl modifying enzymes, compositions and uses thereof |
| CN114044801B (zh) * | 2021-12-02 | 2024-03-19 | 湖北省生物农药工程研究中心 | 一种酪氨酸衍生物及其制备方法和应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4496540A (en) | 1982-12-30 | 1985-01-29 | Biomeasure, Inc. | Therapeutic compounds |
| JPH01146896A (ja) * | 1987-12-04 | 1989-06-08 | Fuji Yakuhin Kogyo Kk | 新規なペプチジルヒドロキサム酸誘導体 |
| IT1283637B1 (it) * | 1996-05-14 | 1998-04-23 | Italfarmaco Spa | Composti ad attivita' antinfiammatoria ed immunosoppressiva |
| AUPO721997A0 (en) * | 1997-06-06 | 1997-07-03 | Queensland Institute Of Medical Research, The | Anticancer compounds |
| CA2423868C (en) * | 2000-09-29 | 2011-06-07 | Prolifix Limited | Carbamic acid compounds comprising an amide linkage as hdac inhibitors |
| WO2003070691A1 (fr) * | 2002-02-21 | 2003-08-28 | Osaka Industrial Promotion Organization | Derive de n-hydroxycarboxamide |
| NZ542445A (en) * | 2003-04-07 | 2008-03-28 | Pharmacyclics Inc | Hydroxamates as therapeutic agents |
-
2004
- 2004-07-05 IT IT001347A patent/ITMI20041347A1/it unknown
-
2005
- 2005-06-07 AT AT05752620T patent/ATE477236T1/de not_active IP Right Cessation
- 2005-06-07 ES ES05752620T patent/ES2350585T3/es active Active
- 2005-06-07 JP JP2007519757A patent/JP4769248B2/ja not_active Expired - Fee Related
- 2005-06-07 BR BRPI0512751-3A patent/BRPI0512751A/pt not_active Application Discontinuation
- 2005-06-07 DE DE602005022868T patent/DE602005022868D1/de active Active
- 2005-06-07 WO PCT/EP2005/052597 patent/WO2006003068A2/en active Application Filing
- 2005-06-07 CN CNB2005800227743A patent/CN100540530C/zh not_active Expired - Fee Related
- 2005-06-07 KR KR1020077000323A patent/KR101183154B1/ko active IP Right Grant
- 2005-06-07 CA CA2570307A patent/CA2570307C/en not_active Expired - Fee Related
- 2005-06-07 EP EP05752620A patent/EP1763507B1/de not_active Not-in-force
- 2005-06-07 US US11/631,645 patent/US7635788B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2008505158A (ja) | 2008-02-21 |
| EP1763507A2 (de) | 2007-03-21 |
| CN100540530C (zh) | 2009-09-16 |
| CA2570307A1 (en) | 2006-01-12 |
| BRPI0512751A (pt) | 2008-04-08 |
| DE602005022868D1 (de) | 2010-09-23 |
| KR101183154B1 (ko) | 2012-09-17 |
| US7635788B2 (en) | 2009-12-22 |
| CN1980886A (zh) | 2007-06-13 |
| US20080076807A1 (en) | 2008-03-27 |
| WO2006003068A2 (en) | 2006-01-12 |
| ITMI20041347A1 (it) | 2004-10-05 |
| JP4769248B2 (ja) | 2011-09-07 |
| WO2006003068A3 (en) | 2006-06-01 |
| CA2570307C (en) | 2012-04-17 |
| ES2350585T3 (es) | 2011-01-25 |
| KR20070038096A (ko) | 2007-04-09 |
| EP1763507B1 (de) | 2010-08-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |