ATE475651T1 - Aryl-substituierte heterozyklen und ihre verwendung - Google Patents
Aryl-substituierte heterozyklen und ihre verwendungInfo
- Publication number
- ATE475651T1 ATE475651T1 AT07725589T AT07725589T ATE475651T1 AT E475651 T1 ATE475651 T1 AT E475651T1 AT 07725589 T AT07725589 T AT 07725589T AT 07725589 T AT07725589 T AT 07725589T AT E475651 T1 ATE475651 T1 AT E475651T1
- Authority
- AT
- Austria
- Prior art keywords
- aryl
- substituted heterocycles
- prophylaxis
- diseases
- treatment
- Prior art date
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 201000010099 disease Diseases 0.000 abstract 2
- 238000011321 prophylaxis Methods 0.000 abstract 2
- 238000011282 treatment Methods 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 125000000623 heterocyclic group Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000009424 thromboembolic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102006025314A DE102006025314A1 (de) | 2006-05-31 | 2006-05-31 | Arylsubstituierte Heterozyklen und ihre Verwendung |
| PCT/EP2007/004693 WO2007137791A1 (de) | 2006-05-31 | 2007-05-25 | Aryl-substituierte heterozyklen und ihre verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE475651T1 true ATE475651T1 (de) | 2010-08-15 |
Family
ID=38474229
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07725589T ATE475651T1 (de) | 2006-05-31 | 2007-05-25 | Aryl-substituierte heterozyklen und ihre verwendung |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8263624B2 (enExample) |
| EP (1) | EP2029546B1 (enExample) |
| JP (1) | JP5178712B2 (enExample) |
| AT (1) | ATE475651T1 (enExample) |
| CA (1) | CA2653666C (enExample) |
| DE (2) | DE102006025314A1 (enExample) |
| ES (1) | ES2347916T3 (enExample) |
| WO (1) | WO2007137791A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101195801B1 (ko) | 2004-06-18 | 2012-11-05 | 밀레니엄 파머슈티컬스 인코퍼레이티드 | Ｘａ 인자 억제제 |
| CA2651303A1 (en) | 2006-05-05 | 2007-11-15 | Millennium Pharmaceuticals, Inc. | Factor xa inhibitors |
| DE102006039589A1 (de) * | 2006-08-24 | 2008-03-06 | Bayer Healthcare Ag | Aminoacyl-Prodrugs II |
| DE102007028319A1 (de) * | 2007-06-20 | 2008-12-24 | Bayer Healthcare Ag | Substituierte Oxazolidinone und ihre Verwendung |
| DE102007028407A1 (de) * | 2007-06-20 | 2008-12-24 | Bayer Healthcare Ag | Substituierte Oxazolidinone und ihre Verwendung |
| US8530501B2 (en) | 2009-12-17 | 2013-09-10 | Millennium Pharmaceuticals, Inc. | Salts and crystalline forms of a factor Xa inhibitor |
| US8742120B2 (en) | 2009-12-17 | 2014-06-03 | Millennium Pharmaceuticals, Inc. | Methods of preparing factor xa inhibitors and salts thereof |
| DE102010028362A1 (de) | 2010-04-29 | 2011-11-03 | Bayer Schering Pharma Aktiengesellschaft | Herstellverfahren |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19962924A1 (de) * | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
| DE10105989A1 (de) * | 2001-02-09 | 2002-08-14 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
| KR100909141B1 (ko) | 2001-09-21 | 2009-07-23 | 브리스톨-마이어스스퀴브컴파니 | 인자 Ｘａ 억제제로서의 락탐-함유 화합물 및 그의 유도체 |
| DE10322469A1 (de) * | 2003-05-19 | 2004-12-16 | Bayer Healthcare Ag | Heterocyclische Verbindungen |
| US7199149B2 (en) * | 2003-10-01 | 2007-04-03 | Bristol Myers Squibb Company | Monocyclic and bicyclic lactams as factor Xa inhibitors |
| KR101195801B1 (ko) * | 2004-06-18 | 2012-11-05 | 밀레니엄 파머슈티컬스 인코퍼레이티드 | Ｘａ 인자 억제제 |
-
2006
- 2006-05-31 DE DE102006025314A patent/DE102006025314A1/de not_active Withdrawn
-
2007
- 2007-05-25 ES ES07725589T patent/ES2347916T3/es active Active
- 2007-05-25 JP JP2009512472A patent/JP5178712B2/ja not_active Expired - Fee Related
- 2007-05-25 CA CA2653666A patent/CA2653666C/en not_active Expired - Fee Related
- 2007-05-25 WO PCT/EP2007/004693 patent/WO2007137791A1/de not_active Ceased
- 2007-05-25 EP EP07725589A patent/EP2029546B1/de not_active Not-in-force
- 2007-05-25 US US12/302,503 patent/US8263624B2/en not_active Expired - Fee Related
- 2007-05-25 AT AT07725589T patent/ATE475651T1/de active
- 2007-05-25 DE DE502007004579T patent/DE502007004579D1/de active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2653666A1 (en) | 2007-12-06 |
| DE102006025314A1 (de) | 2007-12-06 |
| WO2007137791A1 (de) | 2007-12-06 |
| JP2009538846A (ja) | 2009-11-12 |
| ES2347916T3 (es) | 2010-11-25 |
| US8263624B2 (en) | 2012-09-11 |
| US20100029651A1 (en) | 2010-02-04 |
| EP2029546A1 (de) | 2009-03-04 |
| JP5178712B2 (ja) | 2013-04-10 |
| DE502007004579D1 (de) | 2010-09-09 |
| CA2653666C (en) | 2014-09-16 |
| EP2029546B1 (de) | 2010-07-28 |
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