ATE473801T1 - Vorrichtung zur erzeugung von mikrokugeln aus einer flüssigkeit, verfahren zur einspritzung von mindestens einer ersten flüssigkeit in eine zweite flüssigkeit und spritzplatte - Google Patents

Vorrichtung zur erzeugung von mikrokugeln aus einer flüssigkeit, verfahren zur einspritzung von mindestens einer ersten flüssigkeit in eine zweite flüssigkeit und spritzplatte

Info

Publication number
ATE473801T1
ATE473801T1 AT05749421T AT05749421T ATE473801T1 AT E473801 T1 ATE473801 T1 AT E473801T1 AT 05749421 T AT05749421 T AT 05749421T AT 05749421 T AT05749421 T AT 05749421T AT E473801 T1 ATE473801 T1 AT E473801T1
Authority
AT
Austria
Prior art keywords
liquid
fluid
microblades
injecting
producing
Prior art date
Application number
AT05749421T
Other languages
German (de)
English (en)
Inventor
Jeroen Mathijn Wissink
Rijn Cornelis Johannes Maria Van
Wietze Nijdam
Christiaan Goeting
Iwan Rutger Heskamp
Gerrit Jan Veldhuis
Original Assignee
Nanomi B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanomi B V filed Critical Nanomi B V
Application granted granted Critical
Publication of ATE473801T1 publication Critical patent/ATE473801T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/30—Injector mixers
    • B01F25/31—Injector mixers in conduits or tubes through which the main component flows
    • B01F25/314—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit
    • B01F25/3142—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit the conduit having a plurality of openings in the axial direction or in the circumferential direction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/30—Injector mixers
    • B01F25/31—Injector mixers in conduits or tubes through which the main component flows
    • B01F25/314—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit
    • B01F25/3142—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit the conduit having a plurality of openings in the axial direction or in the circumferential direction
    • B01F25/31421—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit the conduit having a plurality of openings in the axial direction or in the circumferential direction the conduit being porous
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/30—Injector mixers
    • B01F25/31—Injector mixers in conduits or tubes through which the main component flows
    • B01F25/314—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit
    • B01F25/3142—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit the conduit having a plurality of openings in the axial direction or in the circumferential direction
    • B01F25/31425—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit the conduit having a plurality of openings in the axial direction or in the circumferential direction with a plurality of perforations in the axial and circumferential direction covering the whole surface
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2215/00—Auxiliary or complementary information in relation with mixing
    • B01F2215/04—Technical information in relation with mixing
    • B01F2215/0413—Numerical information
    • B01F2215/0418—Geometrical information
    • B01F2215/0427—Numerical distance values, e.g. separation, position
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2215/00—Auxiliary or complementary information in relation with mixing
    • B01F2215/04—Technical information in relation with mixing
    • B01F2215/0413—Numerical information
    • B01F2215/0418—Geometrical information
    • B01F2215/0431—Numerical size values, e.g. diameter of a hole or conduit, area, volume, length, width, or ratios thereof
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/0318—Processes
    • Y10T137/0324—With control of flow by a condition or characteristic of a fluid
    • Y10T137/0357—For producing uniform flow
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/206—Flow affected by fluid contact, energy field or coanda effect [e.g., pure fluid device or system]
    • Y10T137/212—System comprising plural fluidic devices or stages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Nozzles (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
AT05749421T 2004-05-25 2005-05-25 Vorrichtung zur erzeugung von mikrokugeln aus einer flüssigkeit, verfahren zur einspritzung von mindestens einer ersten flüssigkeit in eine zweite flüssigkeit und spritzplatte ATE473801T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL1026261A NL1026261C2 (nl) 2004-05-25 2004-05-25 Sproei inrichting met een nozzleplaat voorzien van structuren ter bevordering van self-breakup, een nozzleplaat, alsmede werkwijzen ter vervaardiging en toepassing van een dergelijke nozzleplaat.
PCT/NL2005/000385 WO2005115599A1 (en) 2004-05-25 2005-05-25 Device for generating microspheres from a fluid, method of injecting at least one first fluid into a second fluid, and an injection plate

Publications (1)

Publication Number Publication Date
ATE473801T1 true ATE473801T1 (de) 2010-07-15

Family

ID=34969103

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05749421T ATE473801T1 (de) 2004-05-25 2005-05-25 Vorrichtung zur erzeugung von mikrokugeln aus einer flüssigkeit, verfahren zur einspritzung von mindestens einer ersten flüssigkeit in eine zweite flüssigkeit und spritzplatte

Country Status (9)

Country Link
US (1) US8100348B2 (es)
EP (1) EP1755773B1 (es)
CN (1) CN100563806C (es)
AT (1) ATE473801T1 (es)
DE (1) DE602005022309D1 (es)
DK (1) DK1755773T3 (es)
ES (1) ES2348954T3 (es)
NL (1) NL1026261C2 (es)
WO (1) WO2005115599A1 (es)

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NL1016030C1 (nl) * 2000-08-28 2002-03-01 Aquamarijn Holding B V Sproei inrichting met een nozzleplaat, een nozzleplaat, alsmede werkwijzen ter vervaardiging en voor toepassing van een dergelijke nozzleplaat.
WO2007099475A2 (en) * 2006-03-04 2007-09-07 Udo Von Wimmersperg Gas bubble storage
US20090023189A1 (en) * 2007-05-18 2009-01-22 Applera Corporation Apparatus and methods for preparation of subtantially uniform emulsions containing a particle
CN105344389B (zh) * 2008-05-16 2018-01-02 哈佛大学 微流体系统、方法和装置
EP3663750B1 (en) 2009-05-29 2021-11-03 Life Technologies Corporation Scaffolded nucleic acid polymer particles and methods of making and using
ES2527193T3 (es) 2010-07-09 2015-01-21 Innocore Technologies B.V. Copolímeros multibloque segmentados de fases separadas biodegradables y liberación de polipéptidos biológicamente activos
CN103765068B (zh) * 2011-03-30 2016-09-07 努拜欧有限公司 将多个体积注入或注出液滴
CN103946712A (zh) * 2011-09-30 2014-07-23 不列颠哥伦比亚大学 用于流动控制润湿的方法和设备
US9592503B2 (en) * 2013-01-25 2017-03-14 Gnubio, Inc. System and method for performing droplet inflation
CN105358181B (zh) * 2013-04-22 2019-06-11 加利福尼亚大学董事会 可切换气体和液体释放和输送设备、系统和方法
USD732093S1 (en) * 2014-03-19 2015-06-16 Veeco Ald Inc. Gas tube assembly
USD732092S1 (en) * 2014-03-19 2015-06-16 Veeco Ald Inc. Gas injection plate
US9492594B2 (en) 2014-07-18 2016-11-15 M.A. Med Alliance SA Coating for intraluminal expandable catheter providing contact transfer of drug micro-reservoirs
US11406742B2 (en) 2014-07-18 2022-08-09 M.A. Med Alliance SA Coating for intraluminal expandable catheter providing contact transfer of drug micro-reservoirs
ES2860938T3 (es) * 2014-09-25 2021-10-05 European Molecular Biology Laboratory Dispositivo microfluídico para la generación de muestras combinatorias
FI3352735T3 (fi) 2015-09-21 2023-10-20 Teva Pharmaceuticals Int Gmbh Pitkitetysti vapauttavia olantsapiiniformulaatioita
JP2020511483A (ja) 2017-03-20 2020-04-16 テバ・ファーマシューティカルズ・インターナショナル・ゲーエムベーハーＴｅｖａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｔｅｒｎａｔｉｏｎａｌ ＧｍｂＨ 徐放性オランザピン製剤
CN110799178A (zh) * 2017-04-19 2020-02-14 纳诺米有限公司 用于制备基本上单分散的物质的颗粒的方法和系统
AU2018341389A1 (en) 2017-09-26 2020-04-23 Nanomi B.V. Method for preparing micro-particles by double emulsion technique
CA3114461A1 (en) 2018-10-15 2020-04-23 M.A. Med Alliance SA Coating for intraluminal expandable catheter providing contact transfer of drug micro-reservoirs
US20200376128A1 (en) 2019-06-01 2020-12-03 Lupin Holdings B.V. Monodisperse resorbable polyester polymer compositions, systems, and methods
AU2020316931A1 (en) 2019-07-22 2022-02-24 Nanomi, B.V. Sustained release treprostinil-compound microparticle compositions
CN112495300B (zh) * 2020-11-10 2022-02-01 清华大学 微喷嘴阵列膜及微液滴生成装置
EP4277661A1 (en) 2021-01-18 2023-11-22 Anton Frenkel Pharmaceutical dosage form
WO2023281406A1 (en) 2021-07-06 2023-01-12 Mark Hasleton Treatment of serotonin reuptake inhibitor withdrawal syndrome
CN116036951A (zh) * 2021-10-28 2023-05-02 中国石油天然气股份有限公司 一种数字化配药调剖集成装置及其操作方法
WO2024074585A2 (en) 2022-10-05 2024-04-11 Mireca Medicines Gmbh MICROPARTICLE AND IMPLANT FORMULATIONS FOR cGMP ANALOG THERAPY

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DE2538190C3 (de) * 1975-08-27 1985-04-04 Rumpf, geb. Strupp, Lieselotte Clara, 7500 Karlsruhe Verfahren und Vorrichtung zur kontinuierlichen Fliehkraftsichtung eines stetigen Mengenstroms von körnigem Gut
JPS59145079A (ja) * 1983-02-08 1984-08-20 日鉄鉱業株式会社 粉体粒子の風力分級装置
US4657667A (en) * 1984-04-05 1987-04-14 The University Of Toronto Innovations Foundation Particle classifier
SU1296205A1 (ru) * 1984-12-29 1987-03-15 Дальневосточное высшее инженерное морское училище им.адм.Г.И.Невельского Способ приготовлени водотопливных эмульсий
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JP3511238B2 (ja) 2000-10-13 2004-03-29 独立行政法人食品総合研究所 マイクロスフィアの製造方法および製造装置
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Also Published As

Publication number Publication date
WO2005115599A1 (en) 2005-12-08
EP1755773A1 (en) 2007-02-28
ES2348954T3 (es) 2010-12-17
DK1755773T3 (da) 2010-11-01
US8100348B2 (en) 2012-01-24
DE602005022309D1 (de) 2010-08-26
CN100563806C (zh) 2009-12-02
CN1968737A (zh) 2007-05-23
NL1026261C2 (nl) 2005-11-28
EP1755773B1 (en) 2010-07-14
US20070227591A1 (en) 2007-10-04

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