ATE463581T1 - Phosphatlimitierter induzierbarer promotor und bacillus-expressionssystem - Google Patents
Phosphatlimitierter induzierbarer promotor und bacillus-expressionssystemInfo
- Publication number
- ATE463581T1 ATE463581T1 AT02803271T AT02803271T ATE463581T1 AT E463581 T1 ATE463581 T1 AT E463581T1 AT 02803271 T AT02803271 T AT 02803271T AT 02803271 T AT02803271 T AT 02803271T AT E463581 T1 ATE463581 T1 AT E463581T1
- Authority
- AT
- Austria
- Prior art keywords
- phosphate
- expression system
- inducible promotor
- bacillus expression
- limited
- Prior art date
Links
- 241000193830 Bacillus <bacterium> Species 0.000 title 1
- 230000001939 inductive effect Effects 0.000 title 1
- 235000014469 Bacillus subtilis Nutrition 0.000 abstract 2
- 244000063299 Bacillus subtilis Species 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 238000002818 protein evolution Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/07—Bacillus
- C12R2001/125—Bacillus subtilis ; Hay bacillus; Grass bacillus
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Fertilizers (AREA)
- Treatment Of Sludge (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30892201P | 2001-07-30 | 2001-07-30 | |
| PCT/US2002/023829 WO2003054140A2 (en) | 2001-07-30 | 2002-07-26 | Phosphate limited inducible promoter and a bacillus expression system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE463581T1 true ATE463581T1 (de) | 2010-04-15 |
Family
ID=23195938
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02803271T ATE463581T1 (de) | 2001-07-30 | 2002-07-26 | Phosphatlimitierter induzierbarer promotor und bacillus-expressionssystem |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US7858762B2 (de) |
| EP (1) | EP1412513B1 (de) |
| AT (1) | ATE463581T1 (de) |
| AU (1) | AU2002365118A1 (de) |
| DE (1) | DE60235892D1 (de) |
| DK (1) | DK1412513T3 (de) |
| WO (1) | WO2003054140A2 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009095237A (ja) * | 2006-02-02 | 2009-05-07 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| DK2431470T3 (da) | 2006-11-30 | 2018-01-29 | Novozymes As | DNase expression i rekombinante værtsceller |
| CN101657538A (zh) * | 2006-12-21 | 2010-02-24 | 诺维信股份有限公司 | 在芽孢杆菌属细胞中获得遗传感受态的方法 |
| WO2015029997A1 (ja) * | 2013-08-29 | 2015-03-05 | 国立大学法人東京工業大学 | 融合遺伝子、ベクター、トランスジェニック植物、植物油脂の製造方法、トランスジェニック植物の作出方法、およびトランスジェニック植物の作出用キット |
| HUE061007T2 (hu) * | 2014-06-11 | 2023-05-28 | Univ Duke | Gyors és dinamikus áramlásszabályozásra szolgáló összetételek és módszerek szintetikus matabolikus szelepek segítségével |
| US11203744B2 (en) | 2018-06-21 | 2021-12-21 | Duke University | Compositions and methods for the production of pyruvic acid and related products using dynamic metabolic control |
| US20250243130A1 (en) * | 2024-01-31 | 2025-07-31 | Switch Bioworks, Inc. | Phosphate sensing microbial gene switch |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5411873A (en) | 1984-05-29 | 1995-05-02 | Genencor, Inc. | Process for producing heterologous polypeptides |
| US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5304472A (en) | 1992-11-20 | 1994-04-19 | Genentech, Inc. | Method of controlling polypeptide production in bacterial cells |
| US5789199A (en) | 1994-11-03 | 1998-08-04 | Genentech, Inc. | Process for bacterial production of polypeptides |
| US5922564A (en) | 1997-02-24 | 1999-07-13 | Performance Plants, Inc. | Phosphate-deficiency inducible promoter |
| DE10012283A1 (de) | 2000-03-14 | 2001-09-20 | Thomas Schweder | Wirts-Vektor-Systeme zur phosphatregulierten Überproduktion von Polypeptiden in Becillus |
-
2002
- 2002-07-26 DK DK02803271.2T patent/DK1412513T3/da active
- 2002-07-26 AT AT02803271T patent/ATE463581T1/de not_active IP Right Cessation
- 2002-07-26 AU AU2002365118A patent/AU2002365118A1/en not_active Abandoned
- 2002-07-26 DE DE60235892T patent/DE60235892D1/de not_active Expired - Lifetime
- 2002-07-26 EP EP02803271A patent/EP1412513B1/de not_active Expired - Lifetime
- 2002-07-26 WO PCT/US2002/023829 patent/WO2003054140A2/en not_active Ceased
- 2002-07-26 US US10/483,842 patent/US7858762B2/en not_active Expired - Fee Related
-
2010
- 2010-11-19 US US12/950,880 patent/US8415120B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003054140A2 (en) | 2003-07-03 |
| WO2003054140A9 (en) | 2004-02-26 |
| WO2003054140A3 (en) | 2004-01-22 |
| DK1412513T3 (da) | 2010-07-12 |
| EP1412513B1 (de) | 2010-04-07 |
| US20110262953A1 (en) | 2011-10-27 |
| EP1412513A4 (de) | 2005-04-27 |
| US20050079571A1 (en) | 2005-04-14 |
| US7858762B2 (en) | 2010-12-28 |
| EP1412513A2 (de) | 2004-04-28 |
| DE60235892D1 (de) | 2010-05-20 |
| US8415120B2 (en) | 2013-04-09 |
| AU2002365118A1 (en) | 2003-07-09 |
| AU2002365118A8 (en) | 2003-07-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |