DE60235892D1 - Phosphatlimitierter induzierbarer promotor und bacillus-expressionssystem - Google Patents

Phosphatlimitierter induzierbarer promotor und bacillus-expressionssystem

Info

Publication number
DE60235892D1
DE60235892D1 DE60235892T DE60235892T DE60235892D1 DE 60235892 D1 DE60235892 D1 DE 60235892D1 DE 60235892 T DE60235892 T DE 60235892T DE 60235892 T DE60235892 T DE 60235892T DE 60235892 D1 DE60235892 D1 DE 60235892D1
Authority
DE
Germany
Prior art keywords
phosphatlimited
expression system
inducible promoter
bacillus expression
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60235892T
Other languages
English (en)
Inventor
Katherine D Collier
Edwin Lee
Nicholas Leiva
Thomas B Morrison
Volker Schellenberger
Olga Selifonova
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Danisco US Inc
Original Assignee
Genencor International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genencor International Inc filed Critical Genencor International Inc
Application granted granted Critical
Publication of DE60235892D1 publication Critical patent/DE60235892D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07—Bacillus
    • C12R2001/125—Bacillus subtilis ; Hay bacillus; Grass bacillus

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Fertilizers (AREA)
  • Treatment Of Sludge (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE60235892T 2001-07-30 2002-07-26 Phosphatlimitierter induzierbarer promotor und bacillus-expressionssystem Expired - Lifetime DE60235892D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30892201P 2001-07-30 2001-07-30
PCT/US2002/023829 WO2003054140A2 (en) 2001-07-30 2002-07-26 Phosphate limited inducible promoter and a bacillus expression system

Publications (1)

Publication Number Publication Date
DE60235892D1 true DE60235892D1 (de) 2010-05-20

Family

ID=23195938

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60235892T Expired - Lifetime DE60235892D1 (de) 2001-07-30 2002-07-26 Phosphatlimitierter induzierbarer promotor und bacillus-expressionssystem

Country Status (7)

Country Link
US (2) US7858762B2 (de)
EP (1) EP1412513B1 (de)
AT (1) ATE463581T1 (de)
AU (1) AU2002365118A1 (de)
DE (1) DE60235892D1 (de)
DK (1) DK1412513T3 (de)
WO (1) WO2003054140A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009095237A (ja) * 2006-02-02 2009-05-07 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
CN101541968B (zh) * 2006-11-30 2013-11-13 诺维信公司 重组宿主细胞中的脱氧核糖核酸酶表达
EP2097531B1 (de) * 2006-12-21 2019-09-18 Novozymes Inc. Verfahren zur erzielung von genetischer kompetenz bei bakterienzellen
US10174333B2 (en) 2013-08-29 2019-01-08 Tokyo Institute Of Technology Fused gene, vector, transgenic plant, method for manufacturing vegetable fat or oil, method for constructing transgenic plant, and kit for constructing transgenic plant
GB2528177B (en) 2014-06-11 2019-08-28 Univ Duke Compositions and methods for rapid and dynamic flux control using synthetic metabolic valves
US11203744B2 (en) 2018-06-21 2021-12-21 Duke University Compositions and methods for the production of pyruvic acid and related products using dynamic metabolic control

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5411873A (en) * 1984-05-29 1995-05-02 Genencor, Inc. Process for producing heterologous polypeptides
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5304472A (en) 1992-11-20 1994-04-19 Genentech, Inc. Method of controlling polypeptide production in bacterial cells
US5789199A (en) 1994-11-03 1998-08-04 Genentech, Inc. Process for bacterial production of polypeptides
US5922564A (en) 1997-02-24 1999-07-13 Performance Plants, Inc. Phosphate-deficiency inducible promoter
DE10012283A1 (de) 2000-03-14 2001-09-20 Thomas Schweder Wirts-Vektor-Systeme zur phosphatregulierten Überproduktion von Polypeptiden in Becillus

Also Published As

Publication number Publication date
US20050079571A1 (en) 2005-04-14
EP1412513A2 (de) 2004-04-28
EP1412513A4 (de) 2005-04-27
US20110262953A1 (en) 2011-10-27
WO2003054140A2 (en) 2003-07-03
EP1412513B1 (de) 2010-04-07
WO2003054140A9 (en) 2004-02-26
AU2002365118A1 (en) 2003-07-09
ATE463581T1 (de) 2010-04-15
WO2003054140A3 (en) 2004-01-22
US8415120B2 (en) 2013-04-09
DK1412513T3 (da) 2010-07-12
AU2002365118A8 (en) 2003-07-09
US7858762B2 (en) 2010-12-28

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Legal Events

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8364 No opposition during term of opposition