DK1412513T3 - Phosphatbegrænset inducerbar promotor og Bacillus-ekspressiongssystem - Google Patents

Phosphatbegrænset inducerbar promotor og Bacillus-ekspressiongssystem

Info

Publication number
DK1412513T3
DK1412513T3 DK02803271.2T DK02803271T DK1412513T3 DK 1412513 T3 DK1412513 T3 DK 1412513T3 DK 02803271 T DK02803271 T DK 02803271T DK 1412513 T3 DK1412513 T3 DK 1412513T3
Authority
DK
Denmark
Prior art keywords
expression system
inducible promoter
bacillus expression
phosphate limited
phosphate
Prior art date
Application number
DK02803271.2T
Other languages
English (en)
Inventor
Katherine D Collier
Nicholas Leiva
Thomas B Morrison
Volker Schellenberger
Olga Selifonova
Edwin Lee
Original Assignee
Genencor Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genencor Int filed Critical Genencor Int
Application granted granted Critical
Publication of DK1412513T3 publication Critical patent/DK1412513T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07—Bacillus
    • C12R2001/125—Bacillus subtilis ; Hay bacillus; Grass bacillus

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Fertilizers (AREA)
  • Treatment Of Sludge (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK02803271.2T 2001-07-30 2002-07-26 Phosphatbegrænset inducerbar promotor og Bacillus-ekspressiongssystem DK1412513T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30892201P 2001-07-30 2001-07-30
PCT/US2002/023829 WO2003054140A2 (en) 2001-07-30 2002-07-26 Phosphate limited inducible promoter and a bacillus expression system

Publications (1)

Publication Number Publication Date
DK1412513T3 true DK1412513T3 (da) 2010-07-12

Family

ID=23195938

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02803271.2T DK1412513T3 (da) 2001-07-30 2002-07-26 Phosphatbegrænset inducerbar promotor og Bacillus-ekspressiongssystem

Country Status (7)

Country Link
US (2) US7858762B2 (da)
EP (1) EP1412513B1 (da)
AT (1) ATE463581T1 (da)
AU (1) AU2002365118A1 (da)
DE (1) DE60235892D1 (da)
DK (1) DK1412513T3 (da)
WO (1) WO2003054140A2 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009095237A (ja) 2006-02-02 2009-05-07 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
DK2431470T3 (da) * 2006-11-30 2018-01-29 Novozymes As DNase expression i rekombinante værtsceller
US8389283B2 (en) 2006-12-21 2013-03-05 Novozymes, Inc. Methods of obtaining genetic competence in Bacillus cells
WO2015029997A1 (ja) * 2013-08-29 2015-03-05 国立大学法人東京工業大学 融合遺伝子、ベクター、トランスジェニック植物、植物油脂の製造方法、トランスジェニック植物の作出方法、およびトランスジェニック植物の作出用キット
GB2528177B (en) 2014-06-11 2019-08-28 Univ Duke Compositions and methods for rapid and dynamic flux control using synthetic metabolic valves
WO2019246488A1 (en) 2018-06-21 2019-12-26 Duke University Compositions and methods for the production of pyruvic acid and related products using dynamic metabolic control

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5411873A (en) 1984-05-29 1995-05-02 Genencor, Inc. Process for producing heterologous polypeptides
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5304472A (en) 1992-11-20 1994-04-19 Genentech, Inc. Method of controlling polypeptide production in bacterial cells
US5789199A (en) 1994-11-03 1998-08-04 Genentech, Inc. Process for bacterial production of polypeptides
US5922564A (en) 1997-02-24 1999-07-13 Performance Plants, Inc. Phosphate-deficiency inducible promoter
DE10012283A1 (de) 2000-03-14 2001-09-20 Thomas Schweder Wirts-Vektor-Systeme zur phosphatregulierten Überproduktion von Polypeptiden in Becillus

Also Published As

Publication number Publication date
EP1412513A2 (en) 2004-04-28
ATE463581T1 (de) 2010-04-15
US20110262953A1 (en) 2011-10-27
AU2002365118A1 (en) 2003-07-09
EP1412513B1 (en) 2010-04-07
US7858762B2 (en) 2010-12-28
EP1412513A4 (en) 2005-04-27
WO2003054140A9 (en) 2004-02-26
US20050079571A1 (en) 2005-04-14
US8415120B2 (en) 2013-04-09
DE60235892D1 (de) 2010-05-20
WO2003054140A3 (en) 2004-01-22
AU2002365118A8 (en) 2003-07-09
WO2003054140A2 (en) 2003-07-03

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