ATE460487T1 - Screening-test für ribosomale antibiotika - Google Patents
Screening-test für ribosomale antibiotikaInfo
- Publication number
- ATE460487T1 ATE460487T1 AT07723803T AT07723803T ATE460487T1 AT E460487 T1 ATE460487 T1 AT E460487T1 AT 07723803 T AT07723803 T AT 07723803T AT 07723803 T AT07723803 T AT 07723803T AT E460487 T1 ATE460487 T1 AT E460487T1
- Authority
- AT
- Austria
- Prior art keywords
- ribosomes
- bacterial
- microbial
- cytosolic
- mitochondrial
- Prior art date
Links
- 210000003705 ribosome Anatomy 0.000 title abstract 12
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 229940088710 antibiotic agent Drugs 0.000 title 1
- 238000012216 screening Methods 0.000 title 1
- 230000001580 bacterial effect Effects 0.000 abstract 11
- 230000001086 cytosolic effect Effects 0.000 abstract 4
- 230000000813 microbial effect Effects 0.000 abstract 4
- 230000002438 mitochondrial effect Effects 0.000 abstract 4
- 230000000845 anti-microbial effect Effects 0.000 abstract 3
- 239000000126 substance Substances 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/35—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Mycobacteriaceae (F)
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06006821 | 2006-03-31 | ||
| PCT/EP2007/002861 WO2007112965A1 (en) | 2006-03-31 | 2007-03-30 | Screening assay for ribosomal antibiotics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE460487T1 true ATE460487T1 (de) | 2010-03-15 |
Family
ID=38116101
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07723803T ATE460487T1 (de) | 2006-03-31 | 2007-03-30 | Screening-test für ribosomale antibiotika |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8895260B2 (de) |
| EP (1) | EP2004825B1 (de) |
| JP (1) | JP5080556B2 (de) |
| AT (1) | ATE460487T1 (de) |
| DE (1) | DE602007005235D1 (de) |
| WO (1) | WO2007112965A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2251437B1 (de) * | 2009-05-13 | 2013-12-04 | Hannelore Breitenbach-Koller | Verfahren zur Identifizierung von Verbindungen, die die translationale Aktivität von ribosomalen Proteinen in differentieller mRNA-Expression steuern |
| US9271993B2 (en) | 2010-09-13 | 2016-03-01 | University Of Zurich | Treatment of bacterial infectious diseases |
| EP2844762B1 (de) * | 2012-05-04 | 2017-12-20 | The Regents of The University of California | Nachweis einer antibiotischen suszeptibilität mit sonden für die präribosomale rna |
| CN104374922A (zh) * | 2014-11-26 | 2015-02-25 | 绍兴康知生物科技有限公司 | 一种检测氯霉素的蛋白制备方法 |
| US20240344062A1 (en) * | 2021-08-11 | 2024-10-17 | The Broad Institute, Inc. | RIBOSOMAL RNA (rRNA) VARIANTS POSSESSING ENHANCED PROTEIN PRODUCTION CAPABILITIES |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5336999A (en) * | 1998-08-05 | 2000-02-28 | Trustees Of Tufts College | Novel rrn operon altered bacteria and uses thereof |
-
2007
- 2007-03-30 AT AT07723803T patent/ATE460487T1/de not_active IP Right Cessation
- 2007-03-30 US US12/225,706 patent/US8895260B2/en not_active Expired - Fee Related
- 2007-03-30 WO PCT/EP2007/002861 patent/WO2007112965A1/en not_active Ceased
- 2007-03-30 DE DE602007005235T patent/DE602007005235D1/de active Active
- 2007-03-30 EP EP07723803A patent/EP2004825B1/de not_active Ceased
- 2007-03-30 JP JP2009501961A patent/JP5080556B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US8895260B2 (en) | 2014-11-25 |
| DE602007005235D1 (en) | 2010-04-22 |
| US20090170150A1 (en) | 2009-07-02 |
| WO2007112965A1 (en) | 2007-10-11 |
| EP2004825A1 (de) | 2008-12-24 |
| EP2004825B1 (de) | 2010-03-10 |
| JP5080556B2 (ja) | 2012-11-21 |
| JP2009531041A (ja) | 2009-09-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |