ATE460170T1 - Therapeutische zusammensetzung enthaltend dentritische zellen und ihre verwendung - Google Patents
Therapeutische zusammensetzung enthaltend dentritische zellen und ihre verwendungInfo
- Publication number
- ATE460170T1 ATE460170T1 AT04739563T AT04739563T ATE460170T1 AT E460170 T1 ATE460170 T1 AT E460170T1 AT 04739563 T AT04739563 T AT 04739563T AT 04739563 T AT04739563 T AT 04739563T AT E460170 T1 ATE460170 T1 AT E460170T1
- Authority
- AT
- Austria
- Prior art keywords
- composition containing
- therapeutic composition
- dendritic cells
- relates
- present
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title abstract 4
- 210000004443 dendritic cell Anatomy 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 102000002689 Toll-like receptor Human genes 0.000 abstract 1
- 108020000411 Toll-like receptor Proteins 0.000 abstract 1
- 102000008228 Toll-like receptor 2 Human genes 0.000 abstract 1
- 108010060888 Toll-like receptor 2 Proteins 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 208000037765 diseases and disorders Diseases 0.000 abstract 1
- 108010085650 interferon gamma receptor Proteins 0.000 abstract 1
- 239000000018 receptor agonist Substances 0.000 abstract 1
- 229940044601 receptor agonist Drugs 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0003—Invertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4615—Dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
- A61K39/4622—Antigen presenting cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/464839—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
- C12N5/064—Immunosuppressive dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/24—Interferons [IFN]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pulmonology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03012692A EP1484064A1 (de) | 2003-06-04 | 2003-06-04 | Therapeutische Zusammensetzung enthaltend dentritische Zellen und ihre Verwendung |
PCT/EP2004/005996 WO2004108145A1 (en) | 2003-06-04 | 2004-06-03 | Therapeutical composition containing dentritic cells and use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE460170T1 true ATE460170T1 (de) | 2010-03-15 |
Family
ID=33155152
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04739563T ATE460170T1 (de) | 2003-06-04 | 2004-06-03 | Therapeutische zusammensetzung enthaltend dentritische zellen und ihre verwendung |
Country Status (6)
Country | Link |
---|---|
US (2) | US20070203185A1 (de) |
EP (2) | EP1484064A1 (de) |
AT (1) | ATE460170T1 (de) |
CA (1) | CA2524910A1 (de) |
DE (1) | DE602004025936D1 (de) |
WO (1) | WO2004108145A1 (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19652586A1 (de) * | 1996-12-17 | 1998-06-18 | Biotechnolog Forschung Gmbh | Dhc-Peptid und Mittel |
WO2007122392A1 (en) * | 2006-04-20 | 2007-11-01 | King's College London | Composition comprising a cytotoxic t-cell - inducing adjuvant |
DE102009034779A1 (de) | 2009-07-25 | 2011-02-03 | Emc Microcollections Gmbh | Synthetische Analoga bakterieller Lipopeptide und ihre Anwendung zur Therapie und Prophylaxe allergischer Erkrankungen |
DE102011018499A1 (de) | 2011-04-23 | 2012-10-25 | Emc Microcollections Gmbh | Topische Nanopartikel-Vakzine zur Immunstimulation der dendritischen Zellen in der Haut |
WO2015070031A1 (en) * | 2013-11-08 | 2015-05-14 | University Of Virginia Patent Foundation | Compositions and methods for treating melanoma |
CN107921063A (zh) | 2015-07-02 | 2018-04-17 | 普莱瓦克斯免疫肿瘤学公司 | 用于采用登革病毒与树突细胞的联合疗法的组合物及方法 |
EP3865150A1 (de) | 2015-09-26 | 2021-08-18 | Primevax Immuno-Oncology, Inc. | Kombinationstherapie mit dem dengue-virus und dendritischen zellen |
CA3082779A1 (en) | 2016-11-16 | 2018-05-24 | PrimeVax Immuno-Oncology, Inc. | Combination immunotherapies for treatment of cancer |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6429199B1 (en) * | 1994-07-15 | 2002-08-06 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules for activating dendritic cells |
FR2796961B1 (fr) * | 1999-07-29 | 2003-05-02 | Chu Montpellier | Procede d'obtention de cellules dentritiques, les cellules dentritiques ainsi obtenues et leurs utilisations a des fins cliniques |
EP1291414A1 (de) * | 2001-09-11 | 2003-03-12 | Genethor GmbH | Ex vivo Selektion von T-Zellen mit reduzierter Alloreaktivität (vermindertem Graft-versus-Host Effekt und erhöhtem Graft-verus-Leukemia Effekt) und Gebrauch derseleben bei Knochnemarktransplantationen |
PL372098A1 (en) | 2001-09-06 | 2005-07-11 | Northwest Biotherapeutics, Inc. | Compositions and methods for priming monocytic dendritic cells and t cells for th-1 response |
EP1382352A1 (de) * | 2002-07-19 | 2004-01-21 | GBF Gesellschaft für Biotechnologische Forschung mbH | Bisacyloxypropylcystein-Konjugate und deren Verwendung |
-
2003
- 2003-06-04 EP EP03012692A patent/EP1484064A1/de not_active Withdrawn
-
2004
- 2004-06-03 AT AT04739563T patent/ATE460170T1/de not_active IP Right Cessation
- 2004-06-03 US US10/559,375 patent/US20070203185A1/en not_active Abandoned
- 2004-06-03 CA CA002524910A patent/CA2524910A1/en not_active Abandoned
- 2004-06-03 DE DE602004025936T patent/DE602004025936D1/de not_active Expired - Lifetime
- 2004-06-03 EP EP04739563A patent/EP1641474B1/de not_active Expired - Lifetime
- 2004-06-03 WO PCT/EP2004/005996 patent/WO2004108145A1/en active Application Filing
-
2010
- 2010-09-03 US US12/875,393 patent/US8415152B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1484064A1 (de) | 2004-12-08 |
DE602004025936D1 (de) | 2010-04-22 |
EP1641474B1 (de) | 2010-03-10 |
EP1641474A1 (de) | 2006-04-05 |
WO2004108145A1 (en) | 2004-12-16 |
CA2524910A1 (en) | 2004-12-16 |
US20110070250A1 (en) | 2011-03-24 |
US20070203185A1 (en) | 2007-08-30 |
US8415152B2 (en) | 2013-04-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |