ATE458747T1 - Angiontensin converting enzyme hemmendes peptid - Google Patents

Angiontensin converting enzyme hemmendes peptid

Info

Publication number
ATE458747T1
ATE458747T1 AT04801616T AT04801616T ATE458747T1 AT E458747 T1 ATE458747 T1 AT E458747T1 AT 04801616 T AT04801616 T AT 04801616T AT 04801616 T AT04801616 T AT 04801616T AT E458747 T1 ATE458747 T1 AT E458747T1
Authority
AT
Austria
Prior art keywords
converting enzyme
inhibiting peptide
enzyme inhibiting
angiontensin
peptide
Prior art date
Application number
AT04801616T
Other languages
English (en)
Inventor
Hidekazu Tonouchi
Masayuki Suzuki
Masayuki Uchida
Munehiro Oda
Original Assignee
Meiji Dairies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Dairies Corp filed Critical Meiji Dairies Corp
Application granted granted Critical
Publication of ATE458747T1 publication Critical patent/ATE458747T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/556—Angiotensin converting enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT04801616T 2003-12-01 2004-12-01 Angiontensin converting enzyme hemmendes peptid ATE458747T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003401405 2003-12-01
PCT/JP2004/018235 WO2005061529A1 (ja) 2003-12-01 2004-12-01 アンジオテンシン変換酵素阻害ペプチド

Publications (1)

Publication Number Publication Date
ATE458747T1 true ATE458747T1 (de) 2010-03-15

Family

ID=34708657

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04801616T ATE458747T1 (de) 2003-12-01 2004-12-01 Angiontensin converting enzyme hemmendes peptid

Country Status (11)

Country Link
US (1) US8637463B2 (de)
EP (1) EP1690869B1 (de)
JP (1) JP4628958B2 (de)
KR (1) KR101176673B1 (de)
CN (3) CN1894273B (de)
AT (1) ATE458747T1 (de)
AU (1) AU2004303647B2 (de)
CA (1) CA2549185C (de)
DE (1) DE602004025730D1 (de)
NZ (3) NZ584979A (de)
WO (1) WO2005061529A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090304869A1 (en) * 2005-04-28 2009-12-10 Christianus Jacobus Van Platerink Peptides Having an Ace Inhibiting Effect
BRPI0612183A2 (pt) * 2005-04-28 2010-10-26 Unilever Nv metionina-alanina-prolina e/ou isoleucina-treonina-prolina ou seus sais, seus usos, métodos de tratamento, medicamento, suplemento alimentìcio, alimento, composições, processos de produção de isoleucina-treonina-prolina ou seu sal, de produção de metionina-alanina-prolina ou seu sal e de produção de metionina-alanina-prolina e/ou isoleucina-treonina-prolina
US20090325888A1 (en) * 2005-04-28 2009-12-31 Luppo Edens Peptides having a health benefit and compositions comprising them
WO2006114193A1 (en) * 2005-04-28 2006-11-02 Unilever N.V. Peptides having an ace inhibiting effect
EP1879605A2 (de) * 2005-04-28 2008-01-23 DSMIP Assets B.V. Neue nutrazeutische zusammensetzungen
JP2008208096A (ja) * 2007-02-28 2008-09-11 Kanetoku:Kk クラゲタンパク質由来の新規ペプチドとその用途
ES2324192B1 (es) * 2008-01-30 2010-06-17 PUIG BEAUTY & FASHION GROUP, S.L. Derivados peptidicos utiles en el tratamiento, cuidado o limpieza de la piel, mucosa, cuero cabelludo o uñas.
CN104592350A (zh) * 2013-06-18 2015-05-06 天津商业大学 一种ace抑制肽及其制备方法
FR3017536B1 (fr) * 2014-02-18 2017-05-26 Univ La Rochelle Compositions pour la prevention et/ou le traitement de pathologies liees a l'alpha-glucosidase
CN104356209A (zh) * 2014-08-28 2015-02-18 中国人民解放军第四军医大学 一种降低血压以及保护心脏的多肽
CN109734776B (zh) * 2018-10-23 2020-10-20 渤海大学 一种具有ace抑制活性和dpp-iv抑制活性的三肽
CN113321719B (zh) * 2021-05-20 2022-03-18 澳优乳业（中国）有限公司 一种寡肽及其制备方法与应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4216209A (en) * 1979-03-19 1980-08-05 American Home Products Corporation Tripeptide angiotensin converting enzyme inhibitors
GB9225021D0 (en) * 1992-11-30 1993-01-20 Sandoz Ltd Organic compounds
JP3465923B2 (ja) 1993-03-26 2003-11-10 日本合成化学工業株式会社 新規ペプチド、それを製造する方法及び用途
JP3465922B2 (ja) 1993-03-26 2003-11-10 日本合成化学工業株式会社 新規ペプチド、それを製造する方法及び用途
JP3465921B2 (ja) 1993-03-26 2003-11-10 日本合成化学工業株式会社 新規ペプチド、それを製造する方法及び用途
JP3483212B2 (ja) 1993-10-06 2004-01-06 日本合成化学工業株式会社 新規ペプチド、それを製造する方法及び用途
GB9616351D0 (en) * 1996-08-02 1996-09-11 Smithkline Beecham Biolog Vaccine composition
US6207391B1 (en) * 1998-03-31 2001-03-27 Tularik Inc. High-throughput screening assays for modulators of STAT4 and STAT6 activity
US6261794B1 (en) * 1999-10-14 2001-07-17 Saint Louis University Methods for identifying inhibitors of methionine aminopeptidases
JP2002121199A (ja) 2000-10-13 2002-04-23 Shimaya Co Ltd 新規ペプチドおよびその製造方法
JP2002138100A (ja) * 2000-10-27 2002-05-14 Riken Vitamin Co Ltd アンジオテンシン変換酵素阻害物質
JP2003051163A (ja) * 2001-05-28 2003-02-21 Sharp Corp 信号品質評価方法及び再生装置
US6900033B2 (en) * 2001-06-04 2005-05-31 Human Genome Sciences, Inc. Methods and compositions for modulating ACE-2 activity
MXPA04004805A (es) 2001-11-21 2004-08-11 Morinaga Milk Industry Co Ltd Peptido novedoso que tiene un efecto inhibidor de la enzima convertidora de angiotensina.
DE10225144A1 (de) * 2002-05-29 2003-12-18 Immatics Biotechnologies Gmbh An MHC-Moleküle bindende Tumor-assoziierte Peptide

Also Published As

Publication number Publication date
EP1690869A1 (de) 2006-08-16
US20090163425A1 (en) 2009-06-25
AU2004303647A1 (en) 2005-07-07
NZ587702A (en) 2011-06-30
JPWO2005061529A1 (ja) 2007-12-20
NZ548166A (en) 2010-06-25
CN1894273A (zh) 2007-01-10
CN1894273B (zh) 2011-01-12
KR101176673B1 (ko) 2012-08-23
CA2549185C (en) 2012-10-30
KR20060128899A (ko) 2006-12-14
CN102030817A (zh) 2011-04-27
CN102030817B (zh) 2012-11-21
EP1690869A4 (de) 2007-02-28
CN102030818B (zh) 2013-03-27
EP1690869B1 (de) 2010-02-24
US8637463B2 (en) 2014-01-28
CN102030818A (zh) 2011-04-27
WO2005061529A1 (ja) 2005-07-07
AU2004303647B2 (en) 2010-05-27
JP4628958B2 (ja) 2011-02-09
NZ584979A (en) 2010-10-29
CA2549185A1 (en) 2005-07-07
DE602004025730D1 (en) 2010-04-08

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