ATE452640T1 - Mittel für erkrankungen assoziert mit knochensubstanzverlust - Google Patents

Mittel für erkrankungen assoziert mit knochensubstanzverlust

Info

Publication number
ATE452640T1
ATE452640T1 AT00977860T AT00977860T ATE452640T1 AT E452640 T1 ATE452640 T1 AT E452640T1 AT 00977860 T AT00977860 T AT 00977860T AT 00977860 T AT00977860 T AT 00977860T AT E452640 T1 ATE452640 T1 AT E452640T1
Authority
AT
Austria
Prior art keywords
diseases associated
remedies
bone loss
agonist
decrease
Prior art date
Application number
AT00977860T
Other languages
English (en)
Inventor
Tanaka Masaharu
Oida Hiroji
Original Assignee
Ono Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co filed Critical Ono Pharmaceutical Co
Application granted granted Critical
Publication of ATE452640T1 publication Critical patent/ATE452640T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT00977860T 1999-11-24 2000-11-22 Mittel für erkrankungen assoziert mit knochensubstanzverlust ATE452640T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP33349099 1999-11-24
JP2000056534 2000-03-01
JP2000119188 2000-04-20
PCT/JP2000/008235 WO2001037877A1 (en) 1999-11-24 2000-11-22 Remedies for diseases in association with decrease in bone mass

Publications (1)

Publication Number Publication Date
ATE452640T1 true ATE452640T1 (de) 2010-01-15

Family

ID=27340604

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00977860T ATE452640T1 (de) 1999-11-24 2000-11-22 Mittel für erkrankungen assoziert mit knochensubstanzverlust

Country Status (16)

Country Link
US (1) US6891062B2 (de)
EP (1) EP1232757B1 (de)
JP (1) JP3705360B2 (de)
KR (1) KR100654653B1 (de)
CN (1) CN1262309C (de)
AT (1) ATE452640T1 (de)
AU (1) AU783939B2 (de)
CA (1) CA2391526A1 (de)
DE (1) DE60043587D1 (de)
ES (1) ES2337333T3 (de)
HU (1) HUP0203590A3 (de)
MX (1) MXPA02005173A (de)
NO (1) NO20022442L (de)
NZ (1) NZ519101A (de)
TW (1) TWI247606B (de)
WO (1) WO2001037877A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2296122C2 (ru) * 2001-07-16 2007-03-27 Ф.Хоффманн-Ля Рош Аг Производные 2-пирролидона в качестве простаноидных агонистов и фармацевтическая композиция
IL159996A0 (en) * 2001-07-23 2004-06-20 Ono Pharmaceutical Co Remedies for diseases with bone mass loss having ep4 agonist as the active ingredient
EP1452178A1 (de) * 2001-11-12 2004-09-01 Ono Pharmaceutical Co., Ltd. Bleibend filmartige zubereitung für die topische anwendung, enthaltend ein prostaglandin-derivat
US20040023853A1 (en) * 2002-05-23 2004-02-05 Peri Krishna G. Antagonistic peptides of prostaglandin E2 receptor subtype EP4
EP1878741A3 (de) * 2002-05-23 2008-02-20 Theratechnologies Inc. Antagonistische Peptide aus dem Prostaglandin-E2-Rezeptor vom Untertyp EP4
WO2006075690A1 (ja) * 2005-01-14 2006-07-20 Ono Pharmaceutical Co., Ltd. 安定な医薬組成物
US7531533B2 (en) 2005-01-27 2009-05-12 Asahi Kasei Pharma Corporation 6-Membered heterocyclic compound and use thereof
JPWO2006118173A1 (ja) 2005-04-28 2008-12-18 小野薬品工業株式会社 経皮吸収製剤
US8263137B2 (en) 2005-08-04 2012-09-11 Vertical Pharmaceuticals, Inc. Nutritional supplement for women
US7901710B2 (en) 2005-08-04 2011-03-08 Vertical Pharmaceuticals, Inc. Nutritional supplement for use under physiologically stressful conditions
US7998500B2 (en) 2005-08-04 2011-08-16 Vertical Pharmaceuticals, Inc. Nutritional supplement for women
US8202546B2 (en) 2005-08-04 2012-06-19 Vertical Pharmaceuticals, Inc. Nutritional supplement for use under physiologically stressful conditions
WO2007112084A2 (en) 2006-03-24 2007-10-04 Children's Medical Center Corporation Method to modulate hematopoietic stem cell growth
US9402852B2 (en) * 2006-10-20 2016-08-02 Children's Medical Center Corporation Method to enhance tissue regeneration
EP2085088A4 (de) 2006-10-26 2012-08-29 Ono Pharmaceutical Co Klebende zubereitung
AU2008246579A1 (en) * 2007-05-08 2008-11-13 National University Corporation, Hamamatsu University School Of Medicine Cytotoxic T cell activator comprising EP4 agonist
US20110206781A1 (en) * 2008-05-28 2011-08-25 Zon Leonard I Method to modulate hematopoietic stem cell growth
US9056085B2 (en) 2009-02-03 2015-06-16 Children's Medical Center Corporation Methods for enhancing hematopoietic stem/progenitor cell engraftment
WO2010091052A2 (en) 2009-02-03 2010-08-12 Children's Medical Center Corporation Methods for enhancing hematopoietic stem/progenitor cell engraftment
CA2768154C (en) 2009-07-13 2018-02-13 Irix Pharmaceuticals Synthesis of prostanoids
CN112410298A (zh) 2011-12-02 2021-02-26 菲特治疗公司 增强的干细胞组合物
EP2785350B1 (de) 2011-12-02 2018-05-02 Fate Therapeutics, Inc. Verbesserte verfahren zur behandlung von ischämie
US9440919B2 (en) 2012-07-19 2016-09-13 Cayman Chemical Company, Inc. Difluorolactam compositions for EP4-mediated osteo related diseases and conditions
WO2014144610A1 (en) 2013-03-15 2014-09-18 Cayman Chemical Company, Inc. Lactam compounds as ep4 receptor-selective agonists for use in the treatment of ep4-mediated diseases and conditions
ES2635635T3 (es) 2013-03-15 2017-10-04 Cayman Chemical Company, Incorporated Compuestos de difluorolactama como agonistas selectivos del receptor EP4 para su uso en el tratamiento de enfermedades y afecciones mediadas por EP4
WO2014150602A1 (en) 2013-03-15 2014-09-25 Fate Therapeutics, Inc. Cell potency assay for therapeutic potential
EP3021879A2 (de) 2013-07-19 2016-05-25 Cayman Chemical Company, Incorporated Verfahren, systeme und zusammensetzungen zur förderung der knochenwachstums
KR102311896B1 (ko) 2013-09-30 2021-10-14 패턴 에이피아이 서비시즈 인코포레이티드 복분해를 사용하는 프로스타글란딘 및 프로스타글란딘 중간체의 합성 경로
KR20180058758A (ko) 2015-09-22 2018-06-01 그레이버그 비젼, 인크. 안구 장애의 치료를 위한 화합물 및 조성물

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE390917T1 (de) * 1996-12-20 2008-04-15 Pfizer Prävention und behandlung von skeletterkrankungen mit ep2 subtyp selektiven prostaglandin e2 agonisten
JPH10265454A (ja) * 1997-01-27 1998-10-06 Ono Pharmaceut Co Ltd ３，７−ジチアプロスタン酸誘導体、それらの製造方法およびそれらを有効成分として含有する薬剤
US6124314A (en) * 1997-10-10 2000-09-26 Pfizer Inc. Osteoporosis compounds
GB2330307A (en) * 1998-02-07 1999-04-21 Glaxo Group Ltd EP4 Receptor antagonists as bone resorption inhibitors
US6043275A (en) * 1998-04-16 2000-03-28 Ono Pharmaceutical Co., Ltd. 3,7-dithiaprostanoic acid derivative
TWI249520B (en) * 1998-07-15 2006-02-21 Ono Pharmaceutical Co 5-Thia-omega-substituted phenyl prostaglandin E derivatives, method for producing the same and medicines containing the same as the active ingredient
EP1114816A4 (de) 1998-09-14 2002-09-04 Ono Pharmaceutical Co $g(v)-SUBSTITUIERTE PHENYL-PROSTAGLANDIN-E-DERIVATE UND SIE ALS AKTIVEN BESTANDTEIL ENTHALTENDE MEDIKAMENTE
EP1121133A1 (de) * 1998-10-15 2001-08-08 Merck & Co., Inc. Methoden zur stimulierung der knochenbildung

Also Published As

Publication number Publication date
JP3705360B2 (ja) 2005-10-12
NZ519101A (en) 2004-04-30
US20040209848A1 (en) 2004-10-21
HUP0203590A3 (en) 2006-07-28
AU1548501A (en) 2001-06-04
EP1232757B1 (de) 2009-12-23
EP1232757A4 (de) 2004-06-16
AU783939B2 (en) 2006-01-05
WO2001037877A1 (en) 2001-05-31
KR100654653B1 (ko) 2006-12-07
CN1262309C (zh) 2006-07-05
DE60043587D1 (de) 2010-02-04
MXPA02005173A (es) 2004-02-26
ES2337333T3 (es) 2010-04-23
NO20022442L (no) 2002-07-24
EP1232757A1 (de) 2002-08-21
NO20022442D0 (no) 2002-05-23
HUP0203590A2 (hu) 2003-03-28
US6891062B2 (en) 2005-05-10
TWI247606B (en) 2006-01-21
CN1424918A (zh) 2003-06-18
CA2391526A1 (en) 2001-05-31
KR20020059774A (ko) 2002-07-13

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Legal Events

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