ATE429223T1 - Kombination enthaltend valsartan, amlodipin und hydrochlorothiazid - Google Patents

Kombination enthaltend valsartan, amlodipin und hydrochlorothiazid

Info

Publication number
ATE429223T1
ATE429223T1 AT03732397T AT03732397T ATE429223T1 AT E429223 T1 ATE429223 T1 AT E429223T1 AT 03732397 T AT03732397 T AT 03732397T AT 03732397 T AT03732397 T AT 03732397T AT E429223 T1 ATE429223 T1 AT E429223T1
Authority
AT
Austria
Prior art keywords
hydrochlorothiazide
amlodipine
combination containing
containing valsartan
valsartan
Prior art date
Application number
AT03732397T
Other languages
English (en)
Inventor
Suraj Shetty
Randy Webb
Original Assignee
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29550142&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE429223(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE429223T1 publication Critical patent/ATE429223T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/42Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of mineralocorticosteroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
AT03732397T 2002-05-17 2003-05-16 Kombination enthaltend valsartan, amlodipin und hydrochlorothiazid ATE429223T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38154702P 2002-05-17 2002-05-17
PCT/EP2003/005180 WO2003097045A1 (en) 2002-05-17 2003-05-16 Combination of organic compounds

Publications (1)

Publication Number Publication Date
ATE429223T1 true ATE429223T1 (de) 2009-05-15

Family

ID=29550142

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03732397T ATE429223T1 (de) 2002-05-17 2003-05-16 Kombination enthaltend valsartan, amlodipin und hydrochlorothiazid

Country Status (29)

Country Link
US (3) US20050222137A1 (de)
EP (1) EP1507529B8 (de)
JP (2) JP5132872B2 (de)
KR (2) KR101454070B1 (de)
CN (2) CN101890166A (de)
AR (1) AR040014A1 (de)
AT (1) ATE429223T1 (de)
AU (1) AU2003240261B2 (de)
BR (1) BR0310092A (de)
CA (1) CA2486144C (de)
CY (1) CY1109240T1 (de)
DE (1) DE60327316D1 (de)
DK (1) DK1507529T3 (de)
EC (1) ECSP045429A (de)
EG (1) EG24716A (de)
ES (1) ES2325207T3 (de)
IL (1) IL164925A (de)
MX (1) MXPA04011385A (de)
MY (1) MY138838A (de)
NO (1) NO333011B1 (de)
NZ (1) NZ536557A (de)
PE (1) PE20040439A1 (de)
PL (1) PL372369A1 (de)
PT (1) PT1507529E (de)
RU (1) RU2324482C2 (de)
SI (1) SI1507529T1 (de)
TW (1) TWI358291B (de)
WO (1) WO2003097045A1 (de)
ZA (1) ZA200408737B (de)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EG24716A (en) 2002-05-17 2010-06-07 Novartis Ag Combination of organic compounds
RS20050590A (sr) * 2003-01-31 2007-09-21 Sankyo Company Limited, Lek za profilaksu i tretman arterioskleroze i hipertenzije
WO2004110354A2 (en) 2003-05-15 2004-12-23 Roskamp Research, Llc Method for reducing amyloid deposition, amyloid neurotoxicity and microgliosis
MXPA05012299A (es) * 2003-05-16 2006-01-30 Novartis Ag Composicion farmaceutica que comprende valsartan.
EP1648515B1 (de) * 2003-07-16 2012-11-21 Boehringer Ingelheim International GmbH Chlorthalidon-kombinationen
GB0325605D0 (en) * 2003-11-03 2003-12-10 Novartis Ag Combination of organic compounds
WO2005082329A2 (en) * 2004-02-19 2005-09-09 Ranbaxy Laboratories Limited Process for the preparation of solid dosage forms of valsartan and hydrochlorthiazide
CN100364532C (zh) * 2004-09-30 2008-01-30 江苏恒瑞医药股份有限公司 包含氨氯地平和血管紧张素ⅱ受体抑制剂的组合物
DE602005018387D1 (de) * 2004-10-06 2010-01-28 Eisai R&D Man Co Ltd Medizinische zusammensetzung, verfahren zu ihrer hdihydropyridin-verbindung in einer medizinischen zusammensetzung
RS53141B (sr) * 2004-11-05 2014-06-30 Boehringer Ingelheim International Gmbh Dvoslojna tableta koja sadrži telmisartan i amlodipin
CN1830454A (zh) * 2005-03-10 2006-09-13 刘智仁 盐酸在制备治疗高血压药物中的应用
CA2605306A1 (en) * 2005-04-21 2006-11-02 Santen Pharmaceutical Co., Ltd. Therapeutic agent for keratoconjunctival disorder
CN101247832B (zh) * 2005-06-27 2011-12-28 第一三共株式会社 含有血管紧张素ⅱ受体拮抗剂和钙通道阻断剂的药物制剂
TWI407978B (zh) * 2005-06-27 2013-09-11 Sankyo Co 濕粒狀藥物之製備方法
TWI388345B (zh) * 2005-06-27 2013-03-11 Sankyo Co 用於高血壓之預防或治療之包含血管緊張素ⅱ受體拮抗劑及鈣通道阻斷劑之固體劑型
DE102005031577A1 (de) 2005-07-06 2007-01-11 Bayer Healthcare Ag Pharmazeutische Darreichungsformen enthaltend eine Wirkstoffkombination von Nifedipin und/oder Nisoldipin und einem Angiotensin-II Antagonisten
GT200600371A (es) * 2005-08-17 2007-03-21 Formas de dosis sólidas de valsartan y amlodipina y método para hacer las mismas
AR057882A1 (es) 2005-11-09 2007-12-26 Novartis Ag Compuestos de accion doble de bloqueadores del receptor de angiotensina e inhibidores de endopeptidasa neutra
KR20080108156A (ko) * 2006-04-06 2008-12-11 노파르티스 아게 유기 화합물의 조합물
AR061627A1 (es) * 2006-06-27 2008-09-10 Novartis Ag Formas de dosificacion solidas de valsartan, amlodipina, e hidroclorotiazida, y metodo para elaborarlas
TWI399223B (zh) * 2006-09-15 2013-06-21 Daiichi Sankyo Co Ltd 奧美沙坦酯及氨氯地平之固體劑型
GB2471970A (en) * 2006-09-15 2011-01-19 Daiichi Sankyo Co Ltd Composition comprising olmesartan medoxomil, amlodipine and hydrochlorothiazide
CN101199848B (zh) * 2006-11-11 2012-05-23 深圳奥萨医药有限公司 钙通道阻滞剂/利尿剂/叶酸联用的药物组合物及其用途
AU2008209320B2 (en) * 2007-01-25 2013-05-30 NAIA Metabolic, Inc. Insulin sensitisers and methods of treatment
GB0715628D0 (en) * 2007-08-10 2007-09-19 Generics Uk Ltd Solid valsartan composition
CN101883564B (zh) 2007-10-05 2013-10-16 阿尔茨海默病学会美国公司 使用(-)-尼伐地平对映体减少淀粉状蛋白沉积、淀粉状蛋白神经毒性和小神经胶质增生的方法
WO2009084003A1 (en) * 2007-12-31 2009-07-09 Lupin Limited Pharmaceutical compositions of amlodipine and valsartan
CN101564536B (zh) * 2008-04-21 2010-12-15 鲁南制药集团股份有限公司 一种治疗高血压的药物组合物缓控释制剂
WO2010006103A1 (en) * 2008-07-10 2010-01-14 Ore Pharmaceuticals Inc. Method for enhancing cognition or inhibiting cognitive decline
DE102008059206A1 (de) * 2008-11-27 2010-06-10 Bayer Schering Pharma Aktiengesellschaft Pharmazeutische Darreichungsform enthaltend Nifedipin oder Nisoldipin und einen Angiotensin-II Antagonisten und/oder ein Diuretikum
JP5658172B2 (ja) 2009-01-23 2015-01-21 ハンミ・サイエンス・カンパニー・リミテッド アムロジピン及びロサルタンを含む固形薬剤学的組成物及びその製造方法
RU2398581C1 (ru) * 2009-05-28 2010-09-10 Федеральное государственное учреждение "Российский кардиологический научно-производственный комплекс Федерального агентства по высокотехнологичной медицинской помощи (ФГУ РКНПК Росмедтехнологий) Способ лечения больных гипертрофической кардиомиопатией
US20120107397A1 (en) * 2009-07-03 2012-05-03 Hetero Research Foundation Pharmaceutical compositions of valsartan
WO2011102702A2 (en) 2010-02-16 2011-08-25 Krka, D. D., Novo Mesto Process for the preparation of oral solid dosage forms comprising valsartan
RU2425671C1 (ru) * 2010-06-30 2011-08-10 Государственное образовательное учреждение высшего профессионального образования "Пермская государственная медицинская академия имени академика Е.А. Вагнера Федерального агентства по здравоохранению и социальному развитию" Способ коррекции нарушений функции почек у больных стабильной стенокардией в сочетании с гипертонической болезнью
TR201102067A1 (tr) 2011-03-03 2012-09-21 Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ Valsartan ve amlodipin kombinasyonları.
GB201116993D0 (en) 2011-10-03 2011-11-16 Ems Sa Pharmaceutical compositions of antihypertensives
KR101907881B1 (ko) * 2011-12-30 2018-12-11 한미약품 주식회사 로자탄, 암로디핀 및 히드로클로로티아자이드를 포함하는 고정 용량 조합 제형
JP6231553B2 (ja) 2012-05-07 2017-11-15 バイエル ファーマ アクチエンゲゼルシャフト ニフェジピンおよびカンデサルタン・シレキセチルを含む医薬投与形を製造する方法
WO2013191668A1 (en) 2012-06-22 2013-12-27 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Compositions preventing hypertension comprising soluplus
MX358211B (es) * 2012-07-23 2018-08-10 Landsteiner Scient S A De C V Una composición farmacéutica de liberación comprendiendo hidroclorotiazida, losartán y basilato de amlodipino.
US10918612B2 (en) * 2013-01-22 2021-02-16 Markus Zwickl Combinations with 2-aminoethanesulfonic acid
EP3025711B1 (de) 2013-07-23 2020-11-18 Daiichi Sankyo Company, Limited Medikament zur vorbeugung oder behandlung von hypertonie
CZ2013783A3 (cs) * 2013-10-08 2015-04-15 Zentiva, K. S Stabilní farmaceutická kompozice obsahující amlodipin a valsartan
FR3014694B1 (fr) 2013-12-13 2016-11-11 Roquette Freres Compositions a base de methyl-cyclodextrines pour le traitement et/ou la prevention de maladies par augmentation du taux de cholesterol-hdl
CN104324377B (zh) * 2014-06-19 2017-08-04 西安力邦肇新生物科技有限公司 一种复方降压制剂及其应用
KR101914930B1 (ko) * 2015-03-31 2018-11-05 한미약품 주식회사 암로디핀, 로자탄 및 클로르탈리돈을 포함하는 약제학적 복합 제제
CN105106962A (zh) * 2015-08-29 2015-12-02 西安力邦肇新生物科技有限公司 一种复方降压制剂及其应用
EP3434284A4 (de) * 2016-03-24 2019-11-13 Daiichi Sankyo Company, Limited Medizin zur behandlung von nierenerkrankung
US10319209B2 (en) 2016-06-03 2019-06-11 John Carlton-Foss Method and system for motion analysis and fall prevention
KR102912130B1 (ko) * 2016-11-11 2026-01-14 주식회사유한양행 클로르탈리돈 또는 이의 염 및 암로디핀 또는 이의 염을 포함하는 단일 매트릭스 정제 형태의 약학 조성물 및 이의 제조방법
US10369156B2 (en) 2016-11-15 2019-08-06 The George Institute for Global Health Compositions for the treatment of hypertension
US12521380B2 (en) 2017-01-25 2026-01-13 The George Institute for Global Health Compositions for the treatment of hypertension
DK4101454T3 (da) 2017-01-25 2024-06-17 The George Inst For Global Health Sammensætninger til behandling af hypertension
EP3658140B1 (de) * 2017-02-27 2025-05-21 Idorsia Pharmaceuticals Ltd Kombinationen eines aprocitentan mit weiteren wirkstoffen zur behandlung von resistentem bluthochdruck
MY210547A (en) 2017-11-30 2025-09-30 Idorsia Pharmaceuticals Ltd Combination of a 4-pyrimidinesulfamide derivative with an sglt-2 inhibitor for the treatment of endothelin related diseases
KR20210038931A (ko) * 2018-07-26 2021-04-08 더 조지 인스티튜트 포 글로벌 헬스 고혈압 치료용 조성물
CN111789843A (zh) 2019-04-08 2020-10-20 深圳奥萨医药有限公司 含氨氯地平、氯噻酮和阿米洛利的药物组合物
EP4136103A4 (de) * 2020-04-17 2024-05-15 HB Biotech, Inc. Zusammensetzungen und verfahren zur behandlung neuropsychiatrischer erkrankungen
US11452690B1 (en) 2021-01-27 2022-09-27 ECI Pharmaceuticals, LLC Oral liquid compositions comprising amlodipine besylate and methods of using the same
GR1010320B (el) * 2021-08-04 2022-10-11 Win Medica Φαρμακευτικη Ανωνυμη Εταιρεια, Στερεες φαρμακοτεχνικες μορφες ιρβεσαρτανης, υδροχλωροθειαζιδης και αμλοδιπινης
KR102924710B1 (ko) 2022-07-25 2026-02-09 안국약품 주식회사 암로디핀, 발사르탄 및 인다파미드를 포함하는 약학 제제 및 이의 제조 방법

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8608335D0 (en) 1986-04-04 1986-05-08 Pfizer Ltd Pharmaceutically acceptable salts
US5350771A (en) * 1989-03-22 1994-09-27 Peter K. T. Pang Method and treatment for hypertension using combination therapy involving exogenous calcium and calcium channel blockers
EP0400835A1 (de) 1989-05-15 1990-12-05 Merck & Co. Inc. Substituierte Benzimidazole als Angiotensin II-Hemmer
US5449682A (en) 1990-02-13 1995-09-12 Merck & Co., Inc. Angiotensin II antagonists incorporating a substituted benzyl element
DE122010000024I1 (de) 1990-02-19 2010-07-08 Novartis Ag Acylverbindungen
AU656551B2 (en) * 1990-12-14 1995-02-09 Smithkline Beecham Corporation Angiotensin II receptor blocking compositions
US5656650A (en) * 1990-12-14 1997-08-12 Smithkline Beecham Corp. Angiotensin II receptor blocking compositions
SI9210098B (sl) 1991-02-06 2000-06-30 Dr. Karl Thomae Benzimidazoli, zdravila, ki te spojine vsebujejo, in postopek za njihovo pripravo
NZ242724A (en) * 1991-05-15 1994-09-27 Du Pont Synergistic composition comprising an angiotensin-ii receptor antagonist and a calcium channel blocker
US5492904A (en) 1991-05-15 1996-02-20 E. I. Du Pont De Nemours And Company Composition of angiotensin-II receptor antagonists and calcium channel blockers
US5260325A (en) 1991-08-19 1993-11-09 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking tertiary amides
US5256667A (en) 1991-09-25 1993-10-26 Merck & Co., Inc. Quinazolinones and pyridopyrimidinones
US5202322A (en) 1991-09-25 1993-04-13 Merck & Co., Inc. Quinazolinone and pyridopyrimidine a-II antagonists
WO1993017682A1 (en) 1992-03-04 1993-09-16 Abbott Laboratories Angiotensin ii receptor antagonists
US5206348A (en) 1992-07-23 1993-04-27 Morton International, Inc. Hexahydroxybenzophenone sulfonate esters of diazonaphthoquinone sensitizers and positive photoresists employing same
US5266583A (en) 1992-09-01 1993-11-30 Merck & Co., Inc. Angitotensin II antagonist
US5264447A (en) 1992-09-01 1993-11-23 Merck & Co., Inc. Angiotensin II antagonist
US5721263A (en) 1993-06-07 1998-02-24 Takeda Chemical Industries, Ltd. Pharmaceutical composition for angiotensin II-mediated diseases
CA2125251C (en) 1993-06-07 2005-04-26 Yoshiyuki Inada A pharmaceutical composition for angiotensin ii-mediated diseases
ATE300287T1 (de) 1994-02-08 2005-08-15 Novartis Pharma Gmbh Behandlung von normaldruckglaukom mit valsartan
EP0750500A1 (de) 1994-03-17 1997-01-02 Ciba-Geigy Ag Behandlung von diabetischer nephropatie mit valsartan
GB9406573D0 (en) 1994-03-31 1994-05-25 Merck Sharp & Dohme Medicaments
US5994348A (en) 1995-06-07 1999-11-30 Sanofi Pharmaceutical compositions containing irbesartan
FR2746013B1 (fr) * 1996-03-18 1998-05-29 Sanofi Sa Utilisation de composes antiarythmiques dans la prevention de la mortalite post infarctus
AR006439A1 (es) 1996-03-29 1999-08-25 Smithkline Beecham Corp Dihidrato de eprosartano y un procedimiento para su produccion y formulacion
GB9613470D0 (en) 1996-06-27 1996-08-28 Ciba Geigy Ag Small solid oral dosage form
US5949290A (en) * 1997-01-14 1999-09-07 Bertram; Earnest L. Voltage controlled oscillator tuning apparatus and method
KR20010006280A (ko) 1997-04-11 2001-01-26 어드밴스드 메디슨 인코포레이티드 다수개의 활성 잔기를 제공하는 분자
US5991348A (en) * 1997-08-12 1999-11-23 3Com Corporation Method and apparatus for regenerating symbol timing from a probing signal in a system having non-linear network and codec distortion
DE19820151A1 (de) * 1998-05-06 1999-11-11 Hexal Ag Transdermales therapeutisches System zur Anwendung von Candesartan
US6204281B1 (en) 1998-07-10 2001-03-20 Novartis Ag Method of treatment and pharmaceutical composition
ES2289814T3 (es) * 1998-07-10 2008-02-01 Novartis Pharma Ag Combinacion antihipertensiva de valsartan y bloqueador de canales del calcio.
KR100646716B1 (ko) 1998-12-23 2006-11-17 노파르티스 아게 At-1 또는 at-2 수용체의 증가와 관련된 질환의치료에 있어서 at-1 수용체 길항제 또는 at-2 수용체조절제의 용도
EP1714651A1 (de) 1999-01-26 2006-10-25 Novartis AG Verwendung von Angiotensin II Rezeptorantagonisten zur Behandlung von akutem myokardischen Infarkt
US6395728B2 (en) 1999-07-08 2002-05-28 Novartis Ag Method of treatment and pharmaceutical composition
CN1301545A (zh) 1999-12-27 2001-07-04 王德山 一种复方降血压药
DE10004651A1 (de) * 2000-02-03 2001-08-16 Jutta Dierkes Kombination von blutdrucksenkenden Wirkstoffen mit Wirkstoffen, die den Homocysteinspiegel zu senken vermögen
BR0112665A (pt) 2000-07-19 2003-06-24 Novartis Ag Sais
JP2004514703A (ja) 2000-12-01 2004-05-20 ノバルティス アクチエンゲゼルシャフト 有機化合物の組合せ剤
EG24716A (en) 2002-05-17 2010-06-07 Novartis Ag Combination of organic compounds
GT200600371A (es) 2005-08-17 2007-03-21 Formas de dosis sólidas de valsartan y amlodipina y método para hacer las mismas

Also Published As

Publication number Publication date
EG24716A (en) 2010-06-07
US20090099241A1 (en) 2009-04-16
NZ536557A (en) 2006-10-27
JP5132872B2 (ja) 2013-01-30
DK1507529T3 (da) 2009-08-03
ZA200408737B (en) 2006-02-22
NO333011B1 (no) 2013-02-18
CY1109240T1 (el) 2014-07-02
EP1507529B8 (de) 2010-02-24
IL164925A (en) 2014-04-30
PE20040439A1 (es) 2004-08-20
JP2010209123A (ja) 2010-09-24
WO2003097045A1 (en) 2003-11-27
US20120115854A1 (en) 2012-05-10
KR101454070B1 (ko) 2014-10-23
EP1507529B1 (de) 2009-04-22
KR20110107877A (ko) 2011-10-04
ES2325207T3 (es) 2009-08-28
SI1507529T1 (sl) 2009-10-31
MY138838A (en) 2009-07-31
AU2003240261B2 (en) 2007-06-28
AU2003240261A1 (en) 2003-12-02
ECSP045429A (es) 2005-01-03
TW200406204A (en) 2004-05-01
CN1652777A (zh) 2005-08-10
EP1507529A1 (de) 2005-02-23
MXPA04011385A (es) 2005-02-14
AR040014A1 (es) 2005-03-09
PL372369A1 (en) 2005-07-25
NO20045429L (no) 2004-12-13
CA2486144C (en) 2012-02-07
HK1074773A1 (en) 2005-11-25
RU2004137105A (ru) 2005-09-10
BR0310092A (pt) 2005-02-15
PT1507529E (pt) 2009-07-24
RU2324482C2 (ru) 2008-05-20
US20050222137A1 (en) 2005-10-06
TWI358291B (en) 2012-02-21
JP2005533023A (ja) 2005-11-04
DE60327316D1 (de) 2009-06-04
US8101599B2 (en) 2012-01-24
CN101890166A (zh) 2010-11-24
KR20050000546A (ko) 2005-01-05
IL164925A0 (en) 2005-12-18
CA2486144A1 (en) 2003-11-27

Similar Documents

Publication Publication Date Title
DE60327316D1 (de) Kombination enthaltend valsartan, amlodipin und hydrochlorothiazid
IS8803A (is) Efnasambönd, sem innihalda laktam og afleiður þeirra sem tálmar Xa þáttar
DK1814527T4 (da) Dobbeltlagstablet omfattende telmisartan og amlodipin
DE60314607D1 (de) Polyesterfolie und gasbarrierepolyesterfolie
DK1673750T3 (da) Sikkerhedsovervågningssystem
DE60237997D1 (de) Sicherheitsanordnung
DE60306853D1 (de) Abreisskupplung
DE50015227D1 (de) Packung und Zuschnitt
DE60310069D1 (de) Netzwerksicherheit
EG25683A (en) Benzoxazine derivatives and uses thereof
DK1562918T3 (da) Substituerede benzoxazinoner og anvendelser deraf
IS8220A (is) Bensímídasólafleiður, blöndur sem innihalda þær, framleiðsla þeirra og notkun
MY145576A (en) Benzoxazine derivatives and uses thereof
DE60223540D1 (de) Mundschutz und mundschutzfolie
ZA200602788B (en) Amidomethyl-substituted 2-(4-sulfonilamino)-3-hidroxy-3,4-dihydro-2H-chromen-6-YL-derivatives and drugs containing said compounds
IS7694A (is) Sterasamrunaefnasambönd, framleiðsla og notkun þeirra
ATE462580T1 (de) Dokumentsicherheitsband und gesichertes dokument
IS8182A (is) Díarýlmetýlídenpíperídínafleiður, blöndur og notkun þeirra
FR2849253B1 (fr) Cloture de securite
FI5464U1 (fi) Amlodipiini
DE502004009352D1 (de) Gerbstoffe und konservierungsmittel
ATA4762002A (de) Uv-kaschierter sicherheitsfaden
FIU20030430U0 (fi) Pakkaus ja pakkauksen kansi
SI1562918T1 (sl) Substituirani benzoksazinoni in uporaba le-teh
SE0300310D0 (sv) A method of providing a package with a barrier and the package thus obtained

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1507529

Country of ref document: EP