ATE428925T1 - Automatische probenvorbereitungsverfahren und - vorrichtungen - Google Patents

Automatische probenvorbereitungsverfahren und - vorrichtungen

Info

Publication number
ATE428925T1
ATE428925T1 AT02789816T AT02789816T ATE428925T1 AT E428925 T1 ATE428925 T1 AT E428925T1 AT 02789816 T AT02789816 T AT 02789816T AT 02789816 T AT02789816 T AT 02789816T AT E428925 T1 ATE428925 T1 AT E428925T1
Authority
AT
Austria
Prior art keywords
sample preparation
preparation methods
automatic sample
sample
concentration
Prior art date
Application number
AT02789816T
Other languages
English (en)
Inventor
Duncan Whitney
Original Assignee
Exact Sciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exact Sciences Corp filed Critical Exact Sciences Corp
Application granted granted Critical
Publication of ATE428925T1 publication Critical patent/ATE428925T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38Diluting, dispersing or mixing samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099Characterised by type of test elements
    • G01N2035/00158Elements containing microarrays, i.e. "biochip"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027General features of the devices
    • G01N2035/1032Dilution or aliquotting

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Sampling And Sample Adjustment (AREA)
AT02789816T 2001-11-20 2002-11-20 Automatische probenvorbereitungsverfahren und - vorrichtungen ATE428925T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33165401P 2001-11-20 2001-11-20
PCT/US2002/037452 WO2003044217A2 (en) 2001-11-20 2002-11-20 Automated sample preparation methods and devices

Publications (1)

Publication Number Publication Date
ATE428925T1 true ATE428925T1 (de) 2009-05-15

Family

ID=23294819

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02789816T ATE428925T1 (de) 2001-11-20 2002-11-20 Automatische probenvorbereitungsverfahren und - vorrichtungen

Country Status (8)

Country Link
US (1) US20030204331A1 (de)
EP (1) EP1456648B8 (de)
JP (1) JP2005509871A (de)
AT (1) ATE428925T1 (de)
AU (1) AU2002352858A1 (de)
CA (1) CA2467248A1 (de)
DE (1) DE60232013D1 (de)
WO (1) WO2003044217A2 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6818404B2 (en) 1997-10-23 2004-11-16 Exact Sciences Corporation Methods for detecting hypermethylated nucleic acid in heterogeneous biological samples
US7846733B2 (en) 2000-06-26 2010-12-07 Nugen Technologies, Inc. Methods and compositions for transcription-based nucleic acid amplification
MXPA02012735A (es) * 2000-06-26 2004-04-20 Nugen Tgechnologies Inc Metodos y composiciones para la amplificacion de acido nucleico a base de transcripcion.
DE60142709D1 (de) 2000-12-13 2010-09-09 Nugen Technologies Inc Methoden und zusammensetzungen zur generierung einer vielzahl von kopien von nukleinsäuresequenzen und methoden zur detektion derselben
IL153504A0 (en) 2001-03-09 2003-07-06 Nugen Technologies Inc Methods and compositions for amplification of rna sequences
US7402386B2 (en) 2003-04-14 2008-07-22 Nugen Technologies, Inc. Global amplification using random priming by a composite primer
US7256888B2 (en) 2003-11-07 2007-08-14 Cardial Health 303, Inc. Fluid verification system and method for infusions
US7704730B2 (en) * 2004-10-14 2010-04-27 Meso Scale Technologies, Llc Multiplexed assay methods
US9109256B2 (en) 2004-10-27 2015-08-18 Esoterix Genetic Laboratories, Llc Method for monitoring disease progression or recurrence
US9777314B2 (en) 2005-04-21 2017-10-03 Esoterix Genetic Laboratories, Llc Analysis of heterogeneous nucleic acid samples
EP2477029A1 (de) 2005-06-02 2012-07-18 Fluidigm Corporation Auswertung mit mikrofluiden Aufteilungsvorrichtungen
EP1929046B1 (de) 2005-09-07 2012-07-11 Nugen Technologies, Inc. Verbessertes nukleinsäureamplifikationsverfahren
EP2423334A3 (de) 2006-02-02 2012-04-18 The Board of Trustees of The Leland Stanford Junior University Nicht-invasives fötales genetisches Screening mittels digitaler Analyse
WO2007120675A2 (en) * 2006-04-10 2007-10-25 Duke University Method of detecting genetic mutations
US20080070792A1 (en) * 2006-06-14 2008-03-20 Roland Stoughton Use of highly parallel snp genotyping for fetal diagnosis
EP2589668A1 (de) 2006-06-14 2013-05-08 Verinata Health, Inc Analyse seltener Zellen mittels Probentrennung und DNA-Etiketten
US8137912B2 (en) 2006-06-14 2012-03-20 The General Hospital Corporation Methods for the diagnosis of fetal abnormalities
US20080050739A1 (en) 2006-06-14 2008-02-28 Roland Stoughton Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats
US7901624B2 (en) * 2006-09-26 2011-03-08 Becton, Dickinson And Company Device for automatically adjusting the bacterial inoculum level of a sample
US9114398B2 (en) * 2006-11-29 2015-08-25 Canon U.S. Life Sciences, Inc. Device and method for digital multiplex PCR assays
US20100112590A1 (en) 2007-07-23 2010-05-06 The Chinese University Of Hong Kong Diagnosing Fetal Chromosomal Aneuploidy Using Genomic Sequencing With Enrichment
EA028642B1 (ru) 2007-07-23 2017-12-29 Те Чайниз Юниверсити Ов Гонгконг Способ пренатальной диагностики фетальной хромосомной анэуплоидии
US8034568B2 (en) 2008-02-12 2011-10-11 Nugen Technologies, Inc. Isothermal nucleic acid amplification methods and compositions
WO2009117698A2 (en) * 2008-03-21 2009-09-24 Nugen Technologies, Inc. Methods of rna amplification in the presence of dna
EP3751005A3 (de) 2008-09-20 2021-02-24 The Board of Trustees of the Leland Stanford Junior University Nicht invasive diagnose von fötaler aneuploidie durch sequenzierung
CN104471077B (zh) 2012-05-21 2017-05-24 富鲁达公司 颗粒群的单颗粒分析
US10364467B2 (en) 2015-01-13 2019-07-30 The Chinese University Of Hong Kong Using size and number aberrations in plasma DNA for detecting cancer
PT3261762T (pt) 2015-02-27 2021-11-17 Mastaplex Ltd Recetáculo de amostra, recipiente de amostra e método de utilização
GB201516992D0 (en) 2015-09-25 2015-11-11 Ge Healthcare Bio Sciences Ab Method and system for evaluation of an interaction between an analyte and a ligand using a biosensor
WO2019002935A1 (en) * 2017-06-26 2019-01-03 Bio-Rad Europe Gmbh IN SITU SERIES DILUTION METHOD
ES2959865T3 (es) * 2017-06-29 2024-02-28 Seegene Inc Método y dispositivo para controlar un instrumento de preparación de composición de detección
JP2019066254A (ja) * 2017-09-29 2019-04-25 株式会社安川電機 分注システム及び分注方法
CN112877178B (zh) * 2021-03-10 2022-07-29 太原科技大学 一种放线菌高效分离培养装置

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6033854A (en) * 1991-12-16 2000-03-07 Biotronics Corporation Quantitative PCR using blocking oligonucleotides
US5976798A (en) * 1994-03-30 1999-11-02 Mitokor Methods for detecting mitochondrial mutations diagnostic for Alzheimer's disease and methods for determining heteroplasmy of mitochondrial nucleic acid
US6586193B2 (en) * 1996-04-25 2003-07-01 Genicon Sciences Corporation Analyte assay using particulate labels
US6391622B1 (en) * 1997-04-04 2002-05-21 Caliper Technologies Corp. Closed-loop biochemical analyzers
US6235471B1 (en) * 1997-04-04 2001-05-22 Caliper Technologies Corp. Closed-loop biochemical analyzers
NZ516848A (en) * 1997-06-20 2004-03-26 Ciphergen Biosystems Inc Retentate chromatography apparatus with applications in biology and medicine
WO1999050442A1 (en) * 1998-03-30 1999-10-07 Friedrich Srienc A flow injection flow cytometry system for on-line monitoring of bioreactors and method for monitoring
IL138851A0 (en) * 1998-04-23 2001-10-31 Genentech Inc Quantitative analysis of gene expression
US6440706B1 (en) * 1999-08-02 2002-08-27 Johns Hopkins University Digital amplification
DE10045521A1 (de) * 2000-03-31 2001-10-04 Roche Diagnostics Gmbh Nukleinsäureamplifikationen

Also Published As

Publication number Publication date
EP1456648A2 (de) 2004-09-15
EP1456648A4 (de) 2005-06-29
CA2467248A1 (en) 2003-05-30
JP2005509871A (ja) 2005-04-14
WO2003044217A3 (en) 2003-10-23
EP1456648B8 (de) 2009-07-08
EP1456648B1 (de) 2009-04-15
DE60232013D1 (de) 2009-05-28
US20030204331A1 (en) 2003-10-30
AU2002352858A1 (en) 2003-06-10
WO2003044217A2 (en) 2003-05-30

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