ATE412674T1 - Komplex aus chaperonin und targetprotein, verfahren zu dessen herstellung, verfahren zur stabilisierung des targetproteins, verfahren zur immobilisierung des targetproteins, verfahren zur analyse der struktur des targetproteins, zubereitung mit retardierter freisetzung und verfahren zur herstellung von antikörpern gegen das targetprotein - Google Patents
Komplex aus chaperonin und targetprotein, verfahren zu dessen herstellung, verfahren zur stabilisierung des targetproteins, verfahren zur immobilisierung des targetproteins, verfahren zur analyse der struktur des targetproteins, zubereitung mit retardierter freisetzung und verfahren zur herstellung von antikörpern gegen das targetproteinInfo
- Publication number
- ATE412674T1 ATE412674T1 AT04730054T AT04730054T ATE412674T1 AT E412674 T1 ATE412674 T1 AT E412674T1 AT 04730054 T AT04730054 T AT 04730054T AT 04730054 T AT04730054 T AT 04730054T AT E412674 T1 ATE412674 T1 AT E412674T1
- Authority
- AT
- Austria
- Prior art keywords
- target protein
- chaperonin
- producing
- complex
- immobilizing
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 15
- 102000004169 proteins and genes Human genes 0.000 title abstract 15
- 238000000034 method Methods 0.000 title abstract 8
- 108050001186 Chaperonin Cpn60 Proteins 0.000 title abstract 3
- 102000052603 Chaperonins Human genes 0.000 title abstract 3
- 230000003100 immobilizing effect Effects 0.000 title abstract 2
- 230000000087 stabilizing effect Effects 0.000 title abstract 2
- 238000013268 sustained release Methods 0.000 title abstract 2
- 239000012730 sustained-release form Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 2
- 101710116664 Thermosome subunit Proteins 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/35—Fusion polypeptide containing a fusion for enhanced stability/folding during expression, e.g. fusions with chaperones or thioredoxin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/705—Fusion polypeptide containing domain for protein-protein interaction containing a protein-A fusion
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Wood Science & Technology (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Marine Sciences & Fisheries (AREA)
- Plant Pathology (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003124352 | 2003-04-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE412674T1 true ATE412674T1 (de) | 2008-11-15 |
Family
ID=33410161
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04730054T ATE412674T1 (de) | 2003-04-28 | 2004-04-28 | Komplex aus chaperonin und targetprotein, verfahren zu dessen herstellung, verfahren zur stabilisierung des targetproteins, verfahren zur immobilisierung des targetproteins, verfahren zur analyse der struktur des targetproteins, zubereitung mit retardierter freisetzung und verfahren zur herstellung von antikörpern gegen das targetprotein |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20070059794A1 (de) |
| EP (1) | EP1619208B1 (de) |
| JP (1) | JPWO2004096859A1 (de) |
| AT (1) | ATE412674T1 (de) |
| AU (1) | AU2004234282B2 (de) |
| CA (1) | CA2522263A1 (de) |
| DE (1) | DE602004017447D1 (de) |
| ES (1) | ES2312997T3 (de) |
| WO (1) | WO2004096859A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2583361C (en) * | 2004-10-15 | 2015-08-04 | Sekisui Chemical Co., Ltd. | Gene immunization using an antigen-chaperonin fusion |
| JP2010159218A (ja) * | 2009-01-07 | 2010-07-22 | Sekisui Chem Co Ltd | 融合タンパク質、タンパク質複合体、並びに、目的タンパク質の構造解析方法 |
| JP2010235492A (ja) * | 2009-03-31 | 2010-10-21 | Sekisui Chem Co Ltd | シャペロニン−目的タンパク質複合体及びその製造方法 |
| US9850296B2 (en) | 2010-08-10 | 2017-12-26 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| US9517257B2 (en) | 2010-08-10 | 2016-12-13 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| JP6017422B2 (ja) | 2010-08-10 | 2016-11-02 | エコール・ポリテクニーク・フェデラル・ドゥ・ローザンヌ（ウペエフエル）Ｅｃｏｌｅ Ｐｏｌｙｔｅｃｈｎｉｑｕｅ Ｆｅｄｅｒａｌｅ ｄｅ Ｌａｕｓａｎｎｅ （ＥＰＦＬ） | 赤血球結合療法 |
| US20150094216A1 (en) * | 2012-02-27 | 2015-04-02 | The University Of Kansas | Systems and methods for identifying protein stabilizers |
| US10953101B2 (en) | 2014-02-21 | 2021-03-23 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| US10046056B2 (en) | 2014-02-21 | 2018-08-14 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| US10946079B2 (en) | 2014-02-21 | 2021-03-16 | Ecole Polytechnique Federale De Lausanne | Glycotargeting therapeutics |
| KR20240154672A (ko) | 2014-02-21 | 2024-10-25 | 에꼴 뽈리떼끄닉 뻬데랄 드 로잔느 (으뻬에프엘) | 글리코타겟팅 치료제 |
| EP3638296A1 (de) | 2017-06-16 | 2020-04-22 | The University Of Chicago | Zusammensetzungen und verfahren zur herbeiführung einer immuntoleranz |
| SG11202011078VA (en) | 2018-05-09 | 2020-12-30 | Univ Chicago | Compositions and methods concerning immune tolerance |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU724399B2 (en) * | 1995-08-18 | 2000-09-21 | Sloan-Kettering Institute For Cancer Research | Heat shock protein-based vaccines and immunotherapies |
| ES2439014T3 (es) * | 1998-02-20 | 2014-01-21 | The University Of Miami | Complejo de péptido antigénico-proteína de choque térmico modificada |
| GB9913437D0 (en) * | 1999-06-09 | 1999-08-11 | Medical Res Council | Fusion proteins |
| EP1284986A4 (de) * | 2000-04-17 | 2005-08-24 | James E Rothman | Komplexierung von protein-antigenen und hitzeschockproteinen mittels javelin |
| JP4038555B2 (ja) * | 2000-12-26 | 2008-01-30 | 積水化学工業株式会社 | 組み換え蛋白質の生産方法及び融合蛋白質 |
-
2004
- 2004-04-28 WO PCT/JP2004/006189 patent/WO2004096859A1/ja not_active Ceased
- 2004-04-28 AT AT04730054T patent/ATE412674T1/de not_active IP Right Cessation
- 2004-04-28 DE DE602004017447T patent/DE602004017447D1/de not_active Expired - Fee Related
- 2004-04-28 AU AU2004234282A patent/AU2004234282B2/en not_active Ceased
- 2004-04-28 US US10/554,747 patent/US20070059794A1/en not_active Abandoned
- 2004-04-28 EP EP04730054A patent/EP1619208B1/de not_active Expired - Lifetime
- 2004-04-28 JP JP2004569239A patent/JPWO2004096859A1/ja not_active Withdrawn
- 2004-04-28 CA CA002522263A patent/CA2522263A1/en not_active Abandoned
- 2004-04-28 ES ES04730054T patent/ES2312997T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU2004234282A1 (en) | 2004-11-11 |
| DE602004017447D1 (de) | 2008-12-11 |
| EP1619208A4 (de) | 2006-07-12 |
| EP1619208B1 (de) | 2008-10-29 |
| US20070059794A1 (en) | 2007-03-15 |
| WO2004096859A1 (ja) | 2004-11-11 |
| EP1619208A1 (de) | 2006-01-25 |
| CA2522263A1 (en) | 2004-11-11 |
| JPWO2004096859A1 (ja) | 2006-07-13 |
| AU2004234282B2 (en) | 2008-02-07 |
| ES2312997T3 (es) | 2009-03-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |