ATE412005T1 - Zyklosporinanalog - Google Patents
ZyklosporinanalogInfo
- Publication number
- ATE412005T1 ATE412005T1 AT05809136T AT05809136T ATE412005T1 AT E412005 T1 ATE412005 T1 AT E412005T1 AT 05809136 T AT05809136 T AT 05809136T AT 05809136 T AT05809136 T AT 05809136T AT E412005 T1 ATE412005 T1 AT E412005T1
- Authority
- AT
- Austria
- Prior art keywords
- cyclosporine analogue
- compound
- cyclosporine
- analogue
- hepatitis
- Prior art date
Links
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical class CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 108010069514 Cyclic Peptides Proteins 0.000 abstract 1
- 102000001189 Cyclic Peptides Human genes 0.000 abstract 1
- 208000005176 Hepatitis C Diseases 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2004906673A AU2004906673A0 (en) | 2004-11-22 | New Compound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE412005T1 true ATE412005T1 (de) | 2008-11-15 |
Family
ID=35896035
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05809136T ATE412005T1 (de) | 2004-11-22 | 2005-11-21 | Zyklosporinanalog |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7696167B2 (de) |
| EP (1) | EP1814902B1 (de) |
| JP (1) | JP4735861B2 (de) |
| AT (1) | ATE412005T1 (de) |
| DE (1) | DE602005010607D1 (de) |
| ES (1) | ES2314731T3 (de) |
| WO (1) | WO2006054801A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101273681B1 (ko) | 2005-10-26 | 2013-06-25 | 아스텔라스세이야쿠 가부시키가이샤 | 신규 시클릭 펩티드 화합물 |
| EP2150269B1 (de) * | 2007-05-02 | 2012-11-21 | Astellas Pharma Inc. | Neue zyklische peptidverbindungen |
| AU2011342284C1 (en) | 2010-12-15 | 2017-07-13 | Contravir Pharmaceuticals, Inc. | Cyclosporine analogue molecules modified at amino acid 1 and 3 |
| US8906853B2 (en) | 2012-11-28 | 2014-12-09 | Enanta Pharmaceuticals, Inc. | [N-Me-4-hydroxyleucine]-9-cyclosporin analogues for treatment and prevention of hepatitis C infection |
| JP6130224B2 (ja) * | 2013-05-27 | 2017-05-17 | 公益財団法人微生物化学研究会 | 新規化合物レンツトレハロース、その製造方法、及びその用途、並びに、新規微生物 |
| HK1223843A1 (zh) | 2013-08-26 | 2017-08-11 | Enanta Pharmaceuticals, Inc. | 用於預防或治療丙型肝炎的環孢菌素類似物 |
| US9669095B2 (en) | 2014-11-03 | 2017-06-06 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogues for preventing or treating hepatitis C infection |
| CN112661808B (zh) * | 2020-12-23 | 2022-05-27 | 浙江大学 | 一种酯肽类化合物及其制备方法和应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE110784T1 (de) * | 1987-06-19 | 1994-09-15 | Sandoz Ag | Zyklische peptolide. |
| JPH05271267A (ja) * | 1991-04-23 | 1993-10-19 | Fujisawa Pharmaceut Co Ltd | Ｆｒ９０１４５９物質、その製法及び用途 |
| GB9204466D0 (en) * | 1992-03-02 | 1992-04-15 | Sandoz Ltd | Improvements in or relating to organic compounds |
| CA2426381A1 (en) | 2000-10-19 | 2002-04-25 | Fujisawa Pharmaceutical Co., Ltd. | Cell damage inhibitor |
| GB0320638D0 (en) | 2003-09-03 | 2003-10-01 | Novartis Ag | Organic compounds |
| JP2007015926A (ja) | 2003-10-06 | 2007-01-25 | Fujisawa Pharmaceut Co Ltd | Ｃ型肝炎治療剤 |
| PT1802650E (pt) | 2004-10-01 | 2011-12-30 | Scynexis Inc | Derivados da ciclosporina 3-éter e 3-tioéter substituída para o tratamento e prevenção da infecção de hepatite c |
| ATE490778T1 (de) | 2004-10-01 | 2010-12-15 | Debiopharm Sa | Verwendung von äd-mealaü3-äetvalü4-ciclosporin zur behandlung von hepatitis-c-infektion |
-
2005
- 2005-11-21 ES ES05809136T patent/ES2314731T3/es not_active Expired - Lifetime
- 2005-11-21 JP JP2007522334A patent/JP4735861B2/ja not_active Expired - Fee Related
- 2005-11-21 US US11/719,921 patent/US7696167B2/en not_active Expired - Fee Related
- 2005-11-21 WO PCT/JP2005/021742 patent/WO2006054801A1/en not_active Ceased
- 2005-11-21 EP EP05809136A patent/EP1814902B1/de not_active Expired - Lifetime
- 2005-11-21 AT AT05809136T patent/ATE412005T1/de not_active IP Right Cessation
- 2005-11-21 DE DE602005010607T patent/DE602005010607D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US7696167B2 (en) | 2010-04-13 |
| DE602005010607D1 (de) | 2008-12-04 |
| US20080214447A1 (en) | 2008-09-04 |
| JP4735861B2 (ja) | 2011-07-27 |
| ES2314731T3 (es) | 2009-03-16 |
| JP2008520543A (ja) | 2008-06-19 |
| WO2006054801A1 (en) | 2006-05-26 |
| EP1814902B1 (de) | 2008-10-22 |
| EP1814902A1 (de) | 2007-08-08 |
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| NO20033413D0 (no) | Krystallmodifisering av et syklisk depsipeptid med forbedret aktivitet |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |