ATE411314T1 - Verfahren zur gewinnung der pharmazeutisch aktiven verbindung dolasetron, synthese- zwischenprodukte davon und verfahren zu deren gewinnung - Google Patents

Verfahren zur gewinnung der pharmazeutisch aktiven verbindung dolasetron, synthese- zwischenprodukte davon und verfahren zu deren gewinnung

Info

Publication number
ATE411314T1
ATE411314T1 AT06763874T AT06763874T ATE411314T1 AT E411314 T1 ATE411314 T1 AT E411314T1 AT 06763874 T AT06763874 T AT 06763874T AT 06763874 T AT06763874 T AT 06763874T AT E411314 T1 ATE411314 T1 AT E411314T1
Authority
AT
Austria
Prior art keywords
obtaining
dolasetron
give
active compound
pharmaceutically active
Prior art date
Application number
AT06763874T
Other languages
English (en)
Inventor
Andres Juan Antonio Perez
Barjoan Pere Dalmases
Original Assignee
Inke Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ES200501704A external-priority patent/ES2264901B1/es
Application filed by Inke Sa filed Critical Inke Sa
Application granted granted Critical
Publication of ATE411314T1 publication Critical patent/ATE411314T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT06763874T 2005-07-06 2006-06-26 Verfahren zur gewinnung der pharmazeutisch aktiven verbindung dolasetron, synthese- zwischenprodukte davon und verfahren zu deren gewinnung ATE411314T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200501704A ES2264901B1 (es) 2005-07-06 2005-07-06 Procedimiento para la obtencion de un compuesto farmaceuticamente activo, sus intermedios de sintesis y procedimiento para la obtencion de los mismos.
US70289405P 2005-07-27 2005-07-27

Publications (1)

Publication Number Publication Date
ATE411314T1 true ATE411314T1 (de) 2008-10-15

Family

ID=37027823

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06763874T ATE411314T1 (de) 2005-07-06 2006-06-26 Verfahren zur gewinnung der pharmazeutisch aktiven verbindung dolasetron, synthese- zwischenprodukte davon und verfahren zu deren gewinnung

Country Status (5)

Country Link
EP (1) EP1904492B1 (de)
AT (1) ATE411314T1 (de)
DE (1) DE602006003227D1 (de)
ES (1) ES2314927T3 (de)
WO (1) WO2007003522A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070203175A1 (en) 2006-01-05 2007-08-30 Janos Hajko Productioin of dolasetron
ES2389261T3 (es) 2007-11-13 2012-10-24 Inke, S.A. Compuestos intermedios útiles para preparar dolasetrón
CN102180878B (zh) * 2010-07-02 2013-06-26 成都新恒创药业有限公司 一种多拉司琼异构体或其盐及其制备方法和其应用
CN106749244B (zh) * 2016-11-30 2018-08-31 成都新恒创药业有限公司 一种多拉司琼异构体或其盐的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU895334D0 (en) * 1986-07-30 1990-01-28 Sandoz Ag Process for the preparation of nasal pharmaceutical compositions
ZA878096B (en) * 1986-11-03 1988-04-26 Merrell Dow Pharmaceuticals Inc. Esters of hexahydro-8-hydroxy-2,6-methano-2h-quinolizin-3(4h)-one and related compounds
ZA893008B (en) * 1988-04-29 1989-12-27 Merrell Dow Pharma Process for preparing indole-3-carboxylic acid esters of transhexahydro-8-hydroxy-2,6-methano-2h-quinolizin-3(4h)-one
EP1819705A1 (de) * 2004-11-25 2007-08-22 Cilag Ltd. Verfahren zur herstellung von estern von hexahydro-8-hydroxy-2,6-methano-2h-chinolizin-3(4h)-on

Also Published As

Publication number Publication date
DE602006003227D1 (de) 2008-11-27
EP1904492B1 (de) 2008-10-15
WO2007003522A1 (en) 2007-01-11
ES2314927T3 (es) 2009-03-16
EP1904492A1 (de) 2008-04-02

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Legal Events

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