ATE41033T1 - Kammer zur behandlung von zellen im elektrischen feld. - Google Patents

Kammer zur behandlung von zellen im elektrischen feld.

Info

Publication number
ATE41033T1
ATE41033T1 AT84105313T AT84105313T ATE41033T1 AT E41033 T1 ATE41033 T1 AT E41033T1 AT 84105313 T AT84105313 T AT 84105313T AT 84105313 T AT84105313 T AT 84105313T AT E41033 T1 ATE41033 T1 AT E41033T1
Authority
AT
Austria
Prior art keywords
cells
chamber
treatment
electric field
electrodes
Prior art date
Application number
AT84105313T
Other languages
German (de)
English (en)
Inventor
Christian Matschke
William Michael Arnold
Karl-Heinz Buechner
Ulrich Prof Zimmermann
Original Assignee
Kernforschungsanlage Juelich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kernforschungsanlage Juelich filed Critical Kernforschungsanlage Juelich
Application granted granted Critical
Publication of ATE41033T1 publication Critical patent/ATE41033T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/02—Electrical or electromagnetic means, e.g. for electroporation or for cell fusion

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Electromagnetism (AREA)
  • Physics & Mathematics (AREA)
  • Sustainable Development (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Glass Compositions (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Physical Deposition Of Substances That Are Components Of Semiconductor Devices (AREA)
AT84105313T 1983-05-13 1984-05-10 Kammer zur behandlung von zellen im elektrischen feld. ATE41033T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19833317415 DE3317415A1 (de) 1983-05-13 1983-05-13 Kammer zur behandlung von zellen im elektrischen feld
EP84105313A EP0126389B1 (de) 1983-05-13 1984-05-10 Kammer zur Behandlung von Zellen im elektrischen Feld

Publications (1)

Publication Number Publication Date
ATE41033T1 true ATE41033T1 (de) 1989-03-15

Family

ID=6198871

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84105313T ATE41033T1 (de) 1983-05-13 1984-05-10 Kammer zur behandlung von zellen im elektrischen feld.

Country Status (7)

Country Link
US (1) US4764473A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0126389B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS59216583A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE41033T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3317415A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK237984A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL71757A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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DE3317415A1 (de) * 1983-05-13 1984-11-15 Kernforschungsanlage Jülich GmbH, 5170 Jülich Kammer zur behandlung von zellen im elektrischen feld
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DE3522610A1 (de) * 1985-06-12 1986-12-18 Kernforschungsanlage Jülich GmbH, 5170 Jülich Kammer fuer die behandlung von zellen im elektrischen feld
KR890003947B1 (ko) * 1985-12-11 1989-10-13 가부시기가이샤 시마즈세이사구쇼 세포융합장치
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ATE131081T1 (de) * 1988-01-21 1995-12-15 Massachusetts Inst Technology Molekültransport durch gewebe mit der verwendung von elektroporation.
US5389069A (en) * 1988-01-21 1995-02-14 Massachusetts Institute Of Technology Method and apparatus for in vivo electroporation of remote cells and tissue
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US5126024A (en) * 1989-12-19 1992-06-30 Colorado School Of Mines Apparatus and method for concentrating microorganisms from a liquid medium on an electrode by electrodeposition
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US5545130A (en) * 1992-04-08 1996-08-13 Genetronics, Inc. Flow through electroporation method
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US5350693A (en) * 1993-04-08 1994-09-27 Long Island Jewish Medical Center Multichamber syringe device for fusing cells
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US6074605A (en) * 1995-03-10 2000-06-13 Entremed, Inc. Flow electroporation chamber and method
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US5911223A (en) * 1996-08-09 1999-06-15 Massachusetts Institute Of Technology Introduction of modifying agents into skin by electroporation
US6085115A (en) * 1997-05-22 2000-07-04 Massachusetts Institite Of Technology Biopotential measurement including electroporation of tissue surface
EP0968275B1 (en) * 1997-06-10 2004-02-04 Cyto Pulse Sciences, Inc. Method and apparatus for treating materials with electrical fields having varying orientations
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AU8444698A (en) 1997-06-30 1999-01-25 Centre National De La Recherche Scientifique Improved method for transferring nucleic acid into multicelled eukaryo tic organism cells and combination therefor
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USH2119H1 (en) 1997-11-17 2005-06-07 The United States Of America As Represented By The Secretary Of The Navy Acoustic fusion of aquatic animal tissue cells with biological agents
GB9804246D0 (en) * 1998-02-27 1998-04-22 Babraham The Inst Electropermeabilisation method and apparatus
DE19823047C1 (de) * 1998-05-22 1999-08-26 Fuhr Verfahren und Vorrichtung zur Permeation biologischer Objekte
DE19853658A1 (de) * 1998-11-20 2000-05-31 Evotec Biosystems Ag Verfahren und Vorrichtung zur Manipulation von Partikeln in Mikrosystemen
ATE253983T1 (de) 1998-06-26 2003-11-15 Evotec Ag Elektrodenanordnungen zur erzeugung funktioneller feldbarrieren in mikrosystemen
US6465225B1 (en) 1998-06-29 2002-10-15 Evotec Oai Ag Method and device for manipulating particles in microsystems
FR2792207B1 (fr) * 1999-04-15 2001-06-08 Electricite De France Procede de traitement d'un flux aqueux par electropulsation a champ parallele a l'ecoulement, chambre de pulsation et applications
KR100384924B1 (ko) * 2000-10-12 2003-05-22 이석근 순환성 자기장을 이용한 유전자 발현 조절장치 및 그 방법
US7029916B2 (en) * 2001-02-21 2006-04-18 Maxcyte, Inc. Apparatus and method for flow electroporation of biological samples
DE10116211A1 (de) * 2001-03-27 2002-10-10 Eppendorf Ag Kammer zur Behandlung von in einer Suspension enthaltenen Zellen im elektrischen Feld
DE10127247B4 (de) * 2001-06-05 2006-12-07 Eppendorf Ag Vorrichtung und Verfahren zur elektrischen Behandlung suspendierter biologischer Partikel
US20020192676A1 (en) * 2001-06-18 2002-12-19 Madonna Angelo J. Method for determining if a type of bacteria is present in a mixture
AU2002326717A1 (en) 2001-08-22 2003-03-10 Maxcyte, Inc. Apparatus and method for electroporation of biological samples
US7014744B2 (en) * 2001-08-24 2006-03-21 Applera Corporation Method of purification and concentration using AC fields with a transfer tip
WO2003026599A1 (en) * 2001-09-26 2003-04-03 The Procter & Gamble Company Personal cleansing compositions comprising silicone resin-containing adhesives
US20030170898A1 (en) * 2001-12-04 2003-09-11 Gundersen Martin A. Method for intracellular modifications within living cells using pulsed electric fields
DE60332740D1 (de) * 2002-04-12 2010-07-08 Colorado School Of Mines Golde Verfahren zum nachweis geringer konzentrationen eines zielbakteriums unter verwendung von phagen zur infizierung von zielbakterienzellen
DE10243086A1 (de) 2002-09-16 2004-03-25 Amaxa Gmbh Vorrichtung und Verfahren zur Behandlung von biologischem Material
AU2003277109A1 (en) * 2002-09-30 2004-04-23 Maxcyte, Inc. Apparatus and method for streaming electroporation
JP4753119B2 (ja) 2003-03-14 2011-08-24 セレクティス ソシエテ アノニム 大量処理の生体外エレクトロポレーション法
DE10351833B4 (de) 2003-11-06 2010-03-11 Eppendorf Ag Zellbehandlungskammer
JP4768441B2 (ja) 2003-12-01 2011-09-07 セレクティス ソシエテ アノニム 細胞融合用の不平等電界チャンバ
EP1766057B1 (en) * 2004-05-12 2014-12-17 Maxcyte, Inc. Methods and devices related to a regulated flow electroporation chamber
WO2006058159A2 (en) * 2004-11-23 2006-06-01 The United States Of America As Represented By The Secretary Of Health And Human Services, Nih Methods and compositions for the ex vivo high-throughput detection of protein/protein interactions
US20110097702A1 (en) * 2005-03-31 2011-04-28 Voorhees Kent J Methods and compositions for in situ detection of microorganisms on a surface
WO2006105414A2 (en) * 2005-03-31 2006-10-05 Colorado School Of Mines Apparatus and method for detecting microscopic organisms using microphage
DE102005029414B4 (de) * 2005-06-24 2009-09-03 Forschungszentrum Karlsruhe Gmbh Verfahren zur Bestimmung des durch Elektroporation bewirkenden Aufschlussgrades biologischer Zellen
WO2007024734A2 (en) * 2005-08-19 2007-03-01 Old Dominion Research Foundation Ultrawideband antenna for operation in tissue
US20080124778A1 (en) * 2006-11-29 2008-05-29 Bio-Rad Laboratories, Inc. Electroporation Cuvette with High Field Intensity and Field-Induced Agitation
DE102007005012A1 (de) * 2007-02-01 2008-08-07 Hansa Metallwerke Ag Sanitäre Entkeimungsvorrichtung zur Bekämpfung von Mikroorganismen in Wasser und Verfahren zum Betreiben einer solchen
US8697434B2 (en) * 2008-01-11 2014-04-15 Colorado School Of Mines Detection of phage amplification by SERS nanoparticles
US9441204B2 (en) * 2008-04-03 2016-09-13 Colorado School Of Mines Compositions and methods for detecting Yersinia pestis bacteria
WO2013012276A2 (ko) * 2011-07-19 2013-01-24 주식회사 진바이오시스 수소자기반응 유전자조절기 및 유전자조절 방법
WO2014074322A1 (en) * 2012-11-12 2014-05-15 California Institute Of Technology Devices and methods for nucleic acid extraction capture and concentration using electric fields and centrifugation
CN103451097B (zh) * 2013-08-19 2015-05-27 西安交通大学 一种提高骨髓移植成功率的体外细胞融合系统及方法
US11440000B2 (en) * 2017-07-27 2022-09-13 Biomerieux, Inc. Isolation tube with an endcap
US11904081B2 (en) 2018-05-11 2024-02-20 Lupagen, Inc. Systems and methods for closed loop, real-time modifications of patient cells

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DE3317415A1 (de) * 1983-05-13 1984-11-15 Kernforschungsanlage Jülich GmbH, 5170 Jülich Kammer zur behandlung von zellen im elektrischen feld
US4578168A (en) * 1984-07-27 1986-03-25 Biotronics Apparatus for fusing live cells with electric fields
US4561961A (en) * 1984-07-27 1985-12-31 Biotronics Cooled microscope slide and electrode apparatus for use in live cell fusion system
US4622302A (en) * 1984-08-09 1986-11-11 American National Red Cross Process for inducing membrane fusion under an electric field
DE3522610A1 (de) * 1985-06-12 1986-12-18 Kernforschungsanlage Jülich GmbH, 5170 Jülich Kammer fuer die behandlung von zellen im elektrischen feld
US4695547A (en) * 1986-04-02 1987-09-22 Jeffrey L. Hilliard Probe for electrofusion, electroporation, or like procedure

Also Published As

Publication number Publication date
EP0126389A2 (de) 1984-11-28
JPH0134031B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1989-07-17
DK237984A (da) 1984-11-14
DK237984D0 (da) 1984-05-11
EP0126389B1 (de) 1989-03-01
EP0126389A3 (en) 1986-07-16
US4764473A (en) 1988-08-16
IL71757A0 (en) 1984-09-30
DE3317415A1 (de) 1984-11-15
DE3317415C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1987-07-23
JPS59216583A (ja) 1984-12-06

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Legal Events

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