ATE407T1 - 4-phenyl-thiazolyl-2-oxamat derivate, verfahren zu ihrer herstellung und ihre anwendung bei der behandlung von asthma. - Google Patents
4-phenyl-thiazolyl-2-oxamat derivate, verfahren zu ihrer herstellung und ihre anwendung bei der behandlung von asthma.Info
- Publication number
- ATE407T1 ATE407T1 AT79400293T AT79400293T ATE407T1 AT E407 T1 ATE407 T1 AT E407T1 AT 79400293 T AT79400293 T AT 79400293T AT 79400293 T AT79400293 T AT 79400293T AT E407 T1 ATE407 T1 AT E407T1
- Authority
- AT
- Austria
- Prior art keywords
- thiazolyl
- asthma
- phenyl
- treatment
- derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7818500A FR2429210A1 (fr) | 1978-06-19 | 1978-06-19 | Derives de phenyl-4 thiazolyl-2 oxamates utiles dans le traitement de l'asthme |
EP79400293A EP0006368B1 (fr) | 1978-06-19 | 1979-05-09 | Dérivés de phényl-4 thiazolyl-2 oxamate, procédé pour leur préparation et leur application dans le traitement de l'asthme |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE407T1 true ATE407T1 (de) | 1981-12-15 |
Family
ID=9209775
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT79400293T ATE407T1 (de) | 1978-06-19 | 1979-05-09 | 4-phenyl-thiazolyl-2-oxamat derivate, verfahren zu ihrer herstellung und ihre anwendung bei der behandlung von asthma. |
Country Status (8)
Country | Link |
---|---|
US (1) | US4246271A (ko) |
EP (1) | EP0006368B1 (ko) |
JP (1) | JPS552684A (ko) |
AT (1) | ATE407T1 (ko) |
CA (1) | CA1231952A (ko) |
DE (1) | DE2961352D1 (ko) |
ES (1) | ES481633A1 (ko) |
FR (1) | FR2429210A1 (ko) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2828091A1 (de) * | 1978-06-27 | 1980-01-10 | Boehringer Sohn Ingelheim | 4-substituierte thiazoloxamsaeuren sowie ihre salze und ester |
US4321372A (en) * | 1980-06-16 | 1982-03-23 | Pfizer Inc. | Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and amides |
DE3027527A1 (de) * | 1980-07-19 | 1982-02-18 | Basf Ag, 6700 Ludwigshafen | Neue oxamidsaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel |
FR2494272A1 (fr) * | 1980-11-19 | 1982-05-21 | Fabre Sa Pierre | Derives de l'acide thiazolyl-2 oxamique substitues en position 4 par un radical thienyle ou furyle, leur preparation et leur utilisation comme medicaments |
DE3135250A1 (de) * | 1981-09-05 | 1983-03-17 | Basf Ag, 6700 Ludwigshafen | Tricyclische thiazolyloxamate, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel |
IT1183061B (it) * | 1984-07-31 | 1987-10-05 | Zambon Spa | Composti dotati di attivita'antiallergica |
DE3503773A1 (de) * | 1985-02-05 | 1986-08-07 | Basf Ag, 6700 Ludwigshafen | Thiazolylamide, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung unerwuenschten pflanzenwuchses |
IT1204960B (it) * | 1987-03-25 | 1989-03-10 | Zambon Farmaceutici Spa | Composti dotati di attivita' antiallergica |
DE3807232A1 (de) * | 1988-03-05 | 1989-09-14 | Bayer Ag | Substituierte acrylsaeureester |
JPH0667836B2 (ja) * | 1989-03-01 | 1994-08-31 | 東洋紡績株式会社 | アミド系化合物からなる抗アレルギー剤 |
FR2671552B1 (fr) * | 1991-01-15 | 1993-05-07 | Pf Medicament | Procede de preparation de thiazolyl-2 oxamates d'alkyle. |
JPH07502014A (ja) * | 1991-06-21 | 1995-03-02 | ベーリンガー マンハイム イタリア エス.ピー.エイ. | 気道に対して抗喘息性、抗炎症性活性を有する2−アミノ−4−アリール−チアゾール |
JP2510110B2 (ja) * | 1992-04-07 | 1996-06-26 | 日本航空電子工業株式会社 | 電子部品用導体の製造方法 |
AU5473800A (en) * | 1999-06-11 | 2001-01-02 | Merck & Co., Inc. | Cyclopentyl modulators of chemokine receptor activity |
MY156407A (en) * | 2002-02-28 | 2016-02-26 | Novartis Ag | 5-phenylthiazole derivatives and use as p13 kinase inhibitors |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH486481A (de) * | 1965-03-05 | 1970-02-28 | Ciba Geigy | Verfahren zur Herstellung neuer Nitrothiazolverbindungen |
US4054666A (en) * | 1973-03-23 | 1977-10-18 | American Home Products Corporation | Compositions and methods of treating immediate hypersensitivity reactions with thiazolyl oxamic acid derivatives |
US3966965A (en) * | 1973-03-23 | 1976-06-29 | American Home Products Corporation | Oxamic acid derivatives for the prevention of immediate type hypersensitivity reactions |
-
1978
- 1978-06-19 FR FR7818500A patent/FR2429210A1/fr active Granted
-
1979
- 1979-05-09 AT AT79400293T patent/ATE407T1/de not_active IP Right Cessation
- 1979-05-09 DE DE7979400293T patent/DE2961352D1/de not_active Expired
- 1979-05-09 EP EP79400293A patent/EP0006368B1/fr not_active Expired
- 1979-06-14 US US06/048,371 patent/US4246271A/en not_active Expired - Lifetime
- 1979-06-18 ES ES481633A patent/ES481633A1/es not_active Expired
- 1979-06-19 JP JP7638779A patent/JPS552684A/ja active Granted
- 1979-06-19 CA CA000330121A patent/CA1231952A/fr not_active Expired
Also Published As
Publication number | Publication date |
---|---|
US4246271A (en) | 1981-01-20 |
FR2429210A1 (fr) | 1980-01-18 |
DE2961352D1 (en) | 1982-01-21 |
JPS6251272B2 (ko) | 1987-10-29 |
ES481633A1 (es) | 1980-02-16 |
CA1231952A (fr) | 1988-01-26 |
JPS552684A (en) | 1980-01-10 |
EP0006368A1 (fr) | 1980-01-09 |
EP0006368B1 (fr) | 1981-11-18 |
FR2429210B1 (ko) | 1980-10-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |