ATE40358T1 - 2,3-dihydrobenzofuran-derivate, mehrere verfahren zu ihrer herstellung und sie enthaltende arzneimittel. - Google Patents
2,3-dihydrobenzofuran-derivate, mehrere verfahren zu ihrer herstellung und sie enthaltende arzneimittel.Info
- Publication number
- ATE40358T1 ATE40358T1 AT86401513T AT86401513T ATE40358T1 AT E40358 T1 ATE40358 T1 AT E40358T1 AT 86401513 T AT86401513 T AT 86401513T AT 86401513 T AT86401513 T AT 86401513T AT E40358 T1 ATE40358 T1 AT E40358T1
- Authority
- AT
- Austria
- Prior art keywords
- radical
- carbon atoms
- production
- several processes
- dihydrobenzofuran derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8510459A FR2584723B1 (fr) | 1985-07-09 | 1985-07-09 | Nouveaux derives du dihydro-2,3 benzofuranne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
| EP86401513A EP0213006B1 (fr) | 1985-07-09 | 1986-07-08 | Nouveaux dérivés du dihydro-2,3 benzofuranne, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE40358T1 true ATE40358T1 (de) | 1989-02-15 |
Family
ID=9321095
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86401513T ATE40358T1 (de) | 1985-07-09 | 1986-07-08 | 2,3-dihydrobenzofuran-derivate, mehrere verfahren zu ihrer herstellung und sie enthaltende arzneimittel. |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US4727086A (es) |
| EP (1) | EP0213006B1 (es) |
| JP (1) | JPS6284073A (es) |
| AT (1) | ATE40358T1 (es) |
| AU (1) | AU584718B2 (es) |
| CA (1) | CA1268764A (es) |
| DE (1) | DE3661913D1 (es) |
| DK (1) | DK165953C (es) |
| ES (1) | ES2000481A6 (es) |
| FR (1) | FR2584723B1 (es) |
| GR (1) | GR861778B (es) |
| IE (1) | IE58539B1 (es) |
| NZ (1) | NZ216785A (es) |
| OA (1) | OA08358A (es) |
| PT (1) | PT82945B (es) |
| ZA (1) | ZA865124B (es) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE58555B1 (en) * | 1984-12-10 | 1993-10-06 | Warner Almbert Company | Novel benzothiophenes and benzofurans having antiallergy activity |
| FR2594438B1 (fr) * | 1986-02-14 | 1990-01-26 | Labaz Sanofi Nv | Derives d'indolizine, leur procede de preparation ainsi que les compositions en contenant |
| IL87451A0 (en) * | 1987-09-04 | 1989-01-31 | Tanabe Seiyaku Co | Benzofuran derivatives,their preparation and pharmaceutical compositions containing them |
| TW472051B (en) | 1997-05-23 | 2002-01-11 | Chugai Pharmaceutical Co Ltd | 2,3-dihydrobenzofuran derivatives |
| US6943168B2 (en) | 1998-06-30 | 2005-09-13 | Neuromed Technologies Inc. | Calcium channel inhibitors comprising benzhydril spaced from piperazine |
| US20040266784A1 (en) * | 1998-06-30 | 2004-12-30 | Snutch Terrance P. | Calcium channel inhibitors comprising benzhydril spaced from piperazine |
| US7186726B2 (en) | 1998-06-30 | 2007-03-06 | Neuromed Pharmaceuticals Ltd. | Preferentially substituted calcium channel blockers |
| US20060084660A1 (en) * | 1998-06-30 | 2006-04-20 | Neuromed Technologies Inc. | Calcium channel blockers comprising two benzhydril moieties |
| US6951862B2 (en) | 1998-06-30 | 2005-10-04 | Neuromed Technologies, Inc. | Calcium channel blockers comprising two benzhydril moieties |
| US6387897B1 (en) | 1998-06-30 | 2002-05-14 | Neuromed Technologies, Inc. | Preferentially substituted calcium channel blockers |
| WO2007053710A2 (en) * | 2005-11-01 | 2007-05-10 | Donnelly Corporation | Interior rearview mirror with display |
| US20050227999A1 (en) * | 2004-04-09 | 2005-10-13 | Neuromed Technologies Inc. | Diarylamine derivatives as calcium channel blockers |
| EP2019676A2 (en) * | 2006-05-11 | 2009-02-04 | Neuromed Pharmaceuticals, Ltd. | Method for increasing the bioavailability of benzhydryl piperazine containing compounds |
| FR2954962B1 (fr) | 2010-01-07 | 2012-04-13 | Valeo Materiaux De Friction | Disque d'embrayage et garniture de friction comportant un materiau de friction d'inertie reduite colle sur un clinquant. |
| US8409560B2 (en) | 2011-03-08 | 2013-04-02 | Zalicus Pharmaceuticals Ltd. | Solid dispersion formulations and methods of use thereof |
| MX2013010306A (es) | 2011-03-08 | 2013-12-09 | Zalicus Pharmaceuticals Ltd | Formulaciones de dispersion solida y metodos de uso de las mismas. |
| CN114846001B (zh) * | 2019-12-27 | 2024-01-23 | 南京明德新药研发有限公司 | 苯并稠环类化合物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2891955A (en) * | 1956-11-23 | 1959-06-23 | Merck Ag E | Process of manufacturing isoquinolinium and 5, 6, 7, 8-tetrahydro-isoquinolinium salts |
| US3156688A (en) * | 1962-11-05 | 1964-11-10 | Abbott Lab | Nu-alkyl and nu-aralkyl benzoxacycloalkanemethylamines |
| US4276294A (en) * | 1978-11-30 | 1981-06-30 | Ciba-Geigy Corporation | Benzofurylpiperazines |
| US4291042A (en) * | 1979-01-26 | 1981-09-22 | John Wyeth & Brother Limited | Antidepressant piperidine derivatives |
| US4602035A (en) * | 1983-12-07 | 1986-07-22 | Hoechst-Roussel Pharmaceuticals Inc. | Antidepressant (3-aryl-2,3-dihydrobenzofuran-3-yl)alkylamines |
-
1985
- 1985-07-09 FR FR8510459A patent/FR2584723B1/fr not_active Expired
-
1986
- 1986-06-30 US US06/880,169 patent/US4727086A/en not_active Expired - Fee Related
- 1986-07-04 CA CA000513161A patent/CA1268764A/fr not_active Expired - Lifetime
- 1986-07-08 IE IE183186A patent/IE58539B1/en not_active IP Right Cessation
- 1986-07-08 DE DE8686401513T patent/DE3661913D1/de not_active Expired
- 1986-07-08 AT AT86401513T patent/ATE40358T1/de not_active IP Right Cessation
- 1986-07-08 NZ NZ216785A patent/NZ216785A/xx unknown
- 1986-07-08 GR GR861778A patent/GR861778B/el unknown
- 1986-07-08 AU AU59840/86A patent/AU584718B2/en not_active Ceased
- 1986-07-08 JP JP61160670A patent/JPS6284073A/ja active Granted
- 1986-07-08 EP EP86401513A patent/EP0213006B1/fr not_active Expired
- 1986-07-08 PT PT82945A patent/PT82945B/pt not_active IP Right Cessation
- 1986-07-09 OA OA58900A patent/OA08358A/xx unknown
- 1986-07-09 ES ES8600208A patent/ES2000481A6/es not_active Expired
- 1986-07-09 ZA ZA865124A patent/ZA865124B/xx unknown
- 1986-07-09 DK DK326986A patent/DK165953C/da not_active IP Right Cessation
-
1987
- 1987-07-16 US US07/074,131 patent/US4751230A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DK326986D0 (da) | 1986-07-09 |
| ES2000481A6 (es) | 1988-03-01 |
| FR2584723B1 (fr) | 1988-02-12 |
| DE3661913D1 (en) | 1989-03-02 |
| DK165953B (da) | 1993-02-15 |
| AU5984086A (en) | 1987-01-15 |
| AU584718B2 (en) | 1989-06-01 |
| EP0213006A1 (fr) | 1987-03-04 |
| PT82945A (pt) | 1986-08-01 |
| US4727086A (en) | 1988-02-23 |
| PT82945B (pt) | 1988-07-01 |
| NZ216785A (en) | 1988-10-28 |
| ZA865124B (en) | 1987-03-25 |
| CA1268764A (fr) | 1990-05-08 |
| JPS6284073A (ja) | 1987-04-17 |
| DK326986A (da) | 1987-01-10 |
| EP0213006B1 (fr) | 1989-01-25 |
| JPH0433794B2 (es) | 1992-06-04 |
| FR2584723A1 (fr) | 1987-01-16 |
| DK165953C (da) | 1993-07-05 |
| IE58539B1 (en) | 1993-10-06 |
| US4751230A (en) | 1988-06-14 |
| IE861831L (en) | 1987-01-09 |
| OA08358A (fr) | 1988-02-29 |
| GR861778B (en) | 1986-11-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |